Guanoxabenz

Guanoxabenz is a drug that is used as an antihypertensive agent. It is a centrally acting alpha-2 adrenergic agonist.

Pharmacology

Guanoxabenz works by stimulating alpha-2 adrenergic receptors in the brain, which decreases sympathetic nervous system activity and results in lowered blood pressure. It is similar in action to clonidine and methyldopa.

Medical uses

Guanoxabenz is used for the treatment of hypertension. It can be used alone or in combination with other antihypertensive drugs.

Side effects

Common side effects of guanoxabenz include drowsiness, dry mouth, and constipation. Less common side effects include depression, insomnia, and palpitations.

Contraindications

Guanoxabenz is contraindicated in patients with known hypersensitivity to the drug. It should also be used with caution in patients with severe coronary insufficiency, recent myocardial infarction, or cerebrovascular disease.

See also

• Antihypertensive drug
• Alpha-2 adrenergic receptor

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