Etamiphylline

Etamiphylline is a bronchodilator used for the treatment of asthma. It is a xanthine derivative, similar to theophylline and aminophylline.

Mechanism of Action

Etamiphylline works by relaxing the smooth muscles in the bronchus and bronchioles, thereby opening up the airways and making it easier to breathe. It does this by inhibiting the enzyme phosphodiesterase, which breaks down cyclic AMP. Increased levels of cyclic AMP lead to relaxation of the smooth muscle.

Side Effects

Like other xanthine derivatives, etamiphylline can cause a number of side effects. These can include nausea, vomiting, abdominal pain, and diarrhea. More serious side effects can include arrhythmias, seizures, and insomnia.

Contraindications

Etamiphylline is contraindicated in patients with a history of hypersensitivity to xanthine derivatives. It should also be used with caution in patients with peptic ulcer disease, seizure disorders, and certain heart conditions.

Interactions

Etamiphylline can interact with a number of other medications, including beta blockers, calcium channel blockers, and certain antibiotics. These interactions can lead to increased levels of etamiphylline in the blood, which can increase the risk of side effects.

See Also

• Theophylline
• Aminophylline
• Bronchodilator
• Asthma

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