ABL

ABL gene is a gene that is found in humans and other organisms. It is known for its role in cell division, cell adhesion, and stress response. Mutations in the ABL gene can lead to various health conditions, including certain types of cancer.

Function

The ABL gene provides instructions for making a protein that is involved in several cellular processes. This protein helps regulate the cell cycle, which is the cell's way of replicating itself. It also plays a role in cell adhesion, which is how cells interact and communicate with each other. Additionally, the ABL protein is involved in the cell's response to stress.

Clinical significance

Mutations in the ABL gene can lead to health problems. For example, a specific mutation in this gene is associated with chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow. This mutation results in an abnormal protein that promotes the uncontrolled growth of white blood cells, leading to the symptoms of leukemia.

Other conditions associated with mutations in the ABL gene include acute lymphoblastic leukemia and certain types of lung cancer. Research is ongoing to better understand the role of the ABL gene in these and other health conditions.

See also

• Chronic myeloid leukemia
• Acute lymphoblastic leukemia
• Lung cancer
• Cell cycle
• Cell adhesion

References

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