U-48800: Difference between revisions

Revision as of 12:00, 9 February 2025

U-48800

U-48800 is a synthetic opioid analgesic that was first identified in the 2020s. It is part of the U-series compounds, which are known for their potent opioid effects. U-48800 is structurally related to other compounds in the series, such as U-47700 and U-49900.

Chemical Structure

U-48800 is chemically classified as a benzamide derivative. Its structure includes a phenyl ring and a cyclohexyl group, which are common features in the U-series compounds. The presence of these groups contributes to its high affinity for the mu-opioid receptor, which is responsible for its analgesic properties.

Pharmacology

U-48800 acts as a potent agonist at the mu-opioid receptor, similar to other opioids. This action results in analgesic effects, but also carries the risk of opioid addiction and respiratory depression. Due to its potency, U-48800 has been associated with a high potential for abuse and overdose.

Legal Status

As of the early 2020s, U-48800 has been subject to legal restrictions in several countries due to its potential for abuse and lack of medical use. It is often classified as a controlled substance under various national drug laws.

Related Compounds

Related Pages

References

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-'''U-48800''' is a synthetic [[opioid]] that is part of the [[U-series drugs|U-series]] of opioids. It was first developed in the 1970s by a team at [[Upjohn]], a pharmaceutical company, which is reflected in the 'U' in its name. U-48800 is a structural analog of the earlier opioid [[AH-7921]] and has been sold as a [[designer drug]].
+== U-48800 ==
-==Chemistry==
+'''U-48800''' is a synthetic opioid analgesic that was first identified in the 2020s. It is part of the [[U-series compounds]], which are known for their potent opioid effects. U-48800 is structurally related to other compounds in the series, such as [[U-47700]] and [[U-49900]].
-U-48800 is a member of the [[drug class]] known as [[U-series drugs|U-series opioids]]. These drugs are characterized by a common backbone structure, which is modified to create different analogs. U-48800 is a structural analog of [[AH-7921]], meaning it shares a similar chemical structure but has been modified.
-==Pharmacology==
+[[File:U-48800_structure.png|thumb|right|Chemical structure of U-48800]]
-Like other opioids, U-48800 acts on the [[mu-opioid receptor]], producing effects such as analgesia, sedation, and euphoria. However, the exact mechanism of action and pharmacokinetics of U-48800 are not well understood, as it has not been extensively studied in humans.
-==Effects==
+== Chemical Structure ==
-The effects of U-48800 are similar to those of other opioids and include [[analgesia]], [[sedation]], [[euphoria]], and [[respiratory depression]]. However, due to its status as a designer drug and lack of clinical studies, the exact effects and safety profile of U-48800 are not well known.
+U-48800 is chemically classified as a [[benzamide]] derivative. Its structure includes a [[phenyl]] ring and a [[cyclohexyl]] group, which are common features in the U-series compounds. The presence of these groups contributes to its high affinity for the [[mu-opioid receptor]], which is responsible for its analgesic properties.
-==Legal Status==
+== Pharmacology ==
-U-48800 is a controlled substance in several countries, including the United States, where it is classified as a Schedule I drug under the [[Controlled Substances Act]]. This means it has a high potential for abuse and no accepted medical use.
+U-48800 acts as a potent [[agonist]] at the mu-opioid receptor, similar to other opioids. This action results in analgesic effects, but also carries the risk of [[opioid addiction]] and [[respiratory depression]]. Due to its potency, U-48800 has been associated with a high potential for abuse and overdose.
-==Health Risks==
+== Legal Status ==
-As with other opioids, U-48800 carries a risk of [[overdose]], which can result in respiratory depression, coma, and death. There have been several reported deaths associated with U-48800 use.
+As of the early 2020s, U-48800 has been subject to legal restrictions in several countries due to its potential for abuse and lack of medical use. It is often classified as a [[controlled substance]] under various national drug laws.
-==See Also==
+== Related Compounds ==
 * [[U-47700]]
 * [[U-49900]]
-* [[Fentanyl]]
+* [[AH-7921]]
-* [[Opioid epidemic]]
-==References==
+== Related Pages ==
-<references />
+* [[Opioid]]
+* [[Synthetic opioid]]
+* [[Drug policy]]
+== References ==
+{{Reflist}}
-[[Category:Opioids]]
-[[Category:Designer drugs]]
 [[Category:Synthetic opioids]]
-[[Category:U-series drugs]]
+[[Category:Opioid analgesics]]
-{{pharmacology-stub}}
+[[Category:Controlled substances]]