VU-0238429: Difference between revisions
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== VU-0238429 == | |||
'''VU-0238429''' is a chemical compound that acts as a selective positive allosteric modulator of the [[muscarinic acetylcholine receptor]] subtype M5. It is used primarily in scientific research to study the role of the M5 receptor in various physiological processes. | |||
VU-0238429 is a | |||
== | == Chemical Structure == | ||
The chemical structure of VU-0238429 is characterized by its unique arrangement of atoms, which allows it to interact specifically with the M5 receptor. The structure can be visualized in the image below: | |||
==Research Applications== | [[File:VU0238429_structure.png|thumb|Chemical structure of VU-0238429]] | ||
VU-0238429 has | |||
== Mechanism of Action == | |||
VU-0238429 functions as a positive allosteric modulator, meaning it binds to a site on the M5 receptor distinct from the active site. This binding enhances the receptor's response to its natural ligand, [[acetylcholine]]. By modulating the activity of the M5 receptor, VU-0238429 can influence various signaling pathways within the [[central nervous system]]. | |||
== Research Applications == | |||
Research involving VU-0238429 has provided insights into the physiological and pathological roles of the M5 receptor. Studies have suggested that the M5 receptor may be involved in the regulation of [[dopamine]] release, which has implications for understanding [[neurological disorders]] such as [[Parkinson's disease]] and [[schizophrenia]]. | |||
== Related Compounds == | |||
VU-0238429 is part of a broader class of compounds known as muscarinic receptor modulators. Other compounds in this class target different subtypes of muscarinic receptors, such as M1, M2, M3, and M4, each with distinct physiological effects and research applications. | |||
== Related Pages == | |||
* [[Muscarinic acetylcholine receptor]] | * [[Muscarinic acetylcholine receptor]] | ||
* [[ | * [[Allosteric modulator]] | ||
* [[ | * [[Dopamine]] | ||
* [[ | * [[Parkinson's disease]] | ||
* [[Schizophrenia]] | * [[Schizophrenia]] | ||
== References == | |||
[[Category: | |||
[[Category: | {{Reflist}} | ||
[[Category:Muscarinic receptor modulators]] | |||
[[Category:Research chemicals]] | |||
Revision as of 11:58, 9 February 2025
VU-0238429
VU-0238429 is a chemical compound that acts as a selective positive allosteric modulator of the muscarinic acetylcholine receptor subtype M5. It is used primarily in scientific research to study the role of the M5 receptor in various physiological processes.
Chemical Structure
The chemical structure of VU-0238429 is characterized by its unique arrangement of atoms, which allows it to interact specifically with the M5 receptor. The structure can be visualized in the image below:
Mechanism of Action
VU-0238429 functions as a positive allosteric modulator, meaning it binds to a site on the M5 receptor distinct from the active site. This binding enhances the receptor's response to its natural ligand, acetylcholine. By modulating the activity of the M5 receptor, VU-0238429 can influence various signaling pathways within the central nervous system.
Research Applications
Research involving VU-0238429 has provided insights into the physiological and pathological roles of the M5 receptor. Studies have suggested that the M5 receptor may be involved in the regulation of dopamine release, which has implications for understanding neurological disorders such as Parkinson's disease and schizophrenia.
Related Compounds
VU-0238429 is part of a broader class of compounds known as muscarinic receptor modulators. Other compounds in this class target different subtypes of muscarinic receptors, such as M1, M2, M3, and M4, each with distinct physiological effects and research applications.
Related Pages
References
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