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Latest revision as of 04:24, 7 January 2025
Robert E. Fredrickson
| Birth date | 1932-08-11 |
|---|---|
| Birth place | Minneapolis, Minnesota, USA |
| Died | June 16, 2002 (aged 69) |
| Place of death | Boston, Massachusetts, USA |
| Nationality | American |
| Known for | Fredrickson classification of hyperlipidemia |
Robert E. Fredrickson (August 11, 1932 – June 16, 2002) was an American biochemist and geneticist renowned for his work in the classification of hyperlipidemia. His contributions to the field of lipid metabolism have had a lasting impact on the diagnosis and treatment of lipid disorders.
Early Life and Education[edit]
Robert E. Fredrickson was born in Minneapolis, Minnesota. He attended the University of Minnesota, where he earned his bachelor's degree in biochemistry. He continued his studies at the same institution, obtaining a Ph.D. in genetics.
Career[edit]
Fredrickson began his career at the National Institutes of Health (NIH), where he worked in the National Heart, Lung, and Blood Institute. His research focused on lipid metabolism and the genetic factors influencing lipid disorders.
Fredrickson Classification[edit]
Fredrickson is best known for developing the Fredrickson classification of hyperlipidemia, a system that categorizes lipid disorders based on the pattern of lipoproteins in the blood. This classification system, also known as the World Health Organization (WHO) classification, is used worldwide to diagnose and manage hyperlipidemia.
The Fredrickson classification includes five types of hyperlipidemia:
* Type IIa: Elevated LDL * Type IIb: Elevated LDL and VLDL
- Type III: Familial dysbetalipoproteinemia
- Type IV: Familial hypertriglyceridemia
- Type V: Mixed hyperlipidemia
Each type is associated with different lipid profiles and risks for cardiovascular disease.
Legacy[edit]
Fredrickson's work has been instrumental in advancing the understanding of lipid disorders. His classification system remains a cornerstone in the field of cardiology and endocrinology.
Personal Life[edit]
Fredrickson was married and had three children. He was known for his dedication to research and his passion for teaching.
