FCRL5: Difference between revisions
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'''FCRL5''' | |||
{{Infobox protein | |||
| name = Fc receptor-like protein 5 | |||
| symbol = FCRL5 | |||
| image = <!-- Image removed --> | |||
| width = | |||
| caption = | |||
| HGNCid = 18712 | |||
| OMIM = 606870 | |||
| EntrezGene = 83417 | |||
| RefSeq = NM_052939 | |||
| UniProt = Q96RD9 | |||
| chromosome = 1 | |||
| arm = q | |||
| band = 21.1 | |||
}} | |||
'''Fc receptor-like protein 5''' ('''FCRL5''') is a protein that in humans is encoded by the '''FCRL5''' gene. This gene is part of the [[Fc receptor-like]] family, which is involved in the regulation of the [[immune system]]. | |||
== Function == | == Function == | ||
FCRL5 is expressed on | FCRL5 is a member of the [[immunoglobulin superfamily]] and is primarily expressed on [[B cells]]. It plays a role in the modulation of [[B cell]] receptor signaling and may be involved in the regulation of [[immune response]]. FCRL5 has been implicated in various [[autoimmune diseases]] and [[cancers]], where it may influence the behavior of [[malignant B cells]]. | ||
== Structure == | == Structure == | ||
The FCRL5 protein | The FCRL5 protein contains several [[immunoglobulin-like domains]], which are characteristic of the [[Fc receptor]] family. These domains are important for the protein's ability to bind to [[antigens]] and other molecules involved in [[immune signaling]]. | ||
== Clinical significance == | == Clinical significance == | ||
Alterations in the expression of FCRL5 have been associated with | Alterations in the expression of FCRL5 have been associated with [[chronic lymphocytic leukemia]] and other [[B cell malignancies]]. Research suggests that FCRL5 may serve as a potential [[biomarker]] for certain [[hematological disorders]]. | ||
== Research == | == Research == | ||
Studies are ongoing to better understand the role of FCRL5 in [[immune regulation]] and its potential as a target for [[therapeutic intervention]] in [[autoimmune diseases]] and [[cancer]]. | |||
[[ | |||
== See also == | == See also == | ||
* [[Fc receptor]] | * [[Fc receptor]] | ||
* [[ | * [[B cell]] | ||
* [[ | * [[Immune system]] | ||
== References == | == References == | ||
<references /> | <references/> | ||
== External links == | |||
* [https://www.ncbi.nlm.nih.gov/gene/83417 FCRL5 gene information at NCBI] | |||
* [https://www.uniprot.org/uniprot/Q96RD9 FCRL5 protein information at UniProt] | |||
[[Category:Immune system]] | |||
[[Category:Proteins]] | [[Category:Proteins]] | ||
[[Category:Genes]] | [[Category:Genes on human chromosome 1]] | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
Latest revision as of 17:32, 30 December 2024
Fc receptor-like protein 5 (FCRL5) is a protein that in humans is encoded by the FCRL5 gene. This gene is part of the Fc receptor-like family, which is involved in the regulation of the immune system.
Function[edit]
FCRL5 is a member of the immunoglobulin superfamily and is primarily expressed on B cells. It plays a role in the modulation of B cell receptor signaling and may be involved in the regulation of immune response. FCRL5 has been implicated in various autoimmune diseases and cancers, where it may influence the behavior of malignant B cells.
Structure[edit]
The FCRL5 protein contains several immunoglobulin-like domains, which are characteristic of the Fc receptor family. These domains are important for the protein's ability to bind to antigens and other molecules involved in immune signaling.
Clinical significance[edit]
Alterations in the expression of FCRL5 have been associated with chronic lymphocytic leukemia and other B cell malignancies. Research suggests that FCRL5 may serve as a potential biomarker for certain hematological disorders.
Research[edit]
Studies are ongoing to better understand the role of FCRL5 in immune regulation and its potential as a target for therapeutic intervention in autoimmune diseases and cancer.
See also[edit]
References[edit]
<references/>
