Iga

IgA is a type of antibody that plays a crucial role in the immune system's function in the mucous membranes. The body typically produces IgA antibodies as a first line of defense against harmful pathogens in the mucous membranes, such as those in the respiratory system and gastrointestinal tract.

Structure and Function

IgA antibodies are primarily found in areas of the body that are exposed to the external environment, such as the nose, breathing passages, digestive tract, ears, eyes, and vagina. They are also present in saliva, tears, and breast milk.

The structure of IgA antibodies allows them to bind to specific antigens, which are substances that the immune system recognizes as foreign. This binding process helps to neutralize the threat posed by the antigen, preventing it from causing harm to the body.

Clinical Significance

The level of IgA in the body can be measured through a blood test. Abnormally high or low levels of IgA can indicate a variety of health conditions.

High levels of IgA may be seen in certain autoimmune diseases, chronic infections, and liver diseases. On the other hand, low levels of IgA, a condition known as IgA deficiency, can make individuals more susceptible to infections, particularly those affecting the mucous membranes.

See Also

• Antibody
• Immune system
• Mucous membrane
• IgA deficiency

References

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