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'''Striatum'''
{{Short description|Part of the brain involved in motor and cognitive functions}}
{{Use dmy dates|date=October 2023}}


The '''Striatum''', or the '''striate nucleus''', is a subcortical part of the forebrain. It receives glutamatergic and dopaminergic inputs from different sources and sends output to other components of the basal ganglia. The striatum plays a critical role in the control of movement and reward learning.
==Striatum==
The '''striatum''' is a subcortical part of the [[forebrain]] and a critical component of the [[basal ganglia]] system. It plays a significant role in various functions, including [[motor control]], [[cognition]], [[emotion]], and [[reward]]. The striatum is divided into two main parts: the [[caudate nucleus]] and the [[putamen]].


==Structure==
[[File:Basal ganglia and related structures.svg|thumb|right|Diagram of the basal ganglia, including the striatum.]]


The striatum is divided into a ventral and a dorsal subdivision, based upon function and connections. The ventral striatum consists of the nucleus accumbens and the olfactory tubercle. The dorsal striatum consists of the caudate nucleus and the putamen.
==Anatomy==
The striatum is located deep within the cerebral hemispheres and is the largest component of the basal ganglia. It is primarily composed of two structures:


===Dorsal striatum===
* '''Caudate nucleus''': This C-shaped structure is located adjacent to the lateral ventricles and is involved in various higher neurological functions, including learning and memory.
* '''Putamen''': Situated more laterally, the putamen is involved in regulating movements and influencing various types of learning.


The [[dorsal striatum]] is composed of the [[caudate nucleus]] and the [[putamen]]. It is associated with motor and action planning, skill learning, and habit formation.
The striatum is also functionally divided into the dorsal striatum and the ventral striatum. The dorsal striatum includes the caudate nucleus and putamen, while the ventral striatum includes the [[nucleus accumbens]] and the [[olfactory tubercle]].
 
===Ventral striatum===
 
The [[ventral striatum]] is composed of the [[nucleus accumbens]] and the [[olfactory tubercle]]. It is associated with reward, pleasure, and addiction.


==Function==
==Function==
The striatum is involved in multiple functions:


The striatum coordinates multiple aspects of cognition, including motor and action planning, decision-making, motivation, reinforcement, and reward perception. It is also involved in the perception of time and the recognition of social cues.
* '''Motor control''': The striatum receives input from the [[cerebral cortex]] and is involved in the planning and modulation of movement pathways.
 
* '''Cognitive processes''': It plays a role in various cognitive processes, including decision-making and executive functions.
==Clinical significance==
* '''Reward and reinforcement''': The ventral striatum, particularly the nucleus accumbens, is crucial in the brain's reward system, influencing motivation and reinforcement learning.
* '''Emotional regulation''': The striatum is involved in processing emotions and is linked to various psychiatric disorders.


Dysfunction of the striatum may be associated with a number of disorders, including [[Parkinson's disease]], [[Huntington's disease]], and [[Tourette syndrome]]. It is also implicated in [[schizophrenia]] and [[bipolar disorder]].
==Clinical Significance==
Dysfunction of the striatum is associated with several neurological and psychiatric disorders:


==See also==
* '''[[Parkinson's disease]]''': Characterized by the degeneration of dopaminergic neurons that project to the striatum, leading to motor deficits.
* '''[[Huntington's disease]]''': A genetic disorder that causes the progressive breakdown of nerve cells in the striatum, leading to movement, cognitive, and psychiatric symptoms.
* '''[[Obsessive-compulsive disorder]] (OCD)''': Involves abnormalities in the striatum and its connections, affecting behavior and thought patterns.
* '''[[Addiction]]''': The striatum is involved in the reward circuitry of the brain, and its dysfunction can contribute to addictive behaviors.


==Related pages==
* [[Basal ganglia]]
* [[Basal ganglia]]
* [[Caudate nucleus]]
* [[Caudate nucleus]]
* [[Putamen]]
* [[Putamen]]
* [[Nucleus accumbens]]
* [[Nucleus accumbens]]
* [[Olfactory tubercle]]
* [[Parkinson's disease]]
 
* [[Huntington's disease]]
==References==
 
<references />


[[Category:Neuroanatomy]]
[[Category:Neuroanatomy]]
[[Category:Basal ganglia]]
[[Category:Basal ganglia]]
[[Category:Striatum]]
{{stub}}
{{dictionary-stub1}}
<gallery>
File:Cortical_surface_with_an_overlay_of_the_basal_ganglia_and_thalamus.jpg|Striatum
File:Corticostriatal_Pathway.jpg|Striatum
File:Striatum_Structural_MRI.png|Striatum
File:Dendritic_spines.jpg|Striatum
File:Basalganglien.png|Striatum
File:Basal_ganglia_circuits.svg|Striatum
File:Overview_of_reward_structures_in_the_human_brain.jpg|Striatum
File:Striatum_coronal_sections.gif|Striatum
File:Striatum_sagittal_sections.gif|Striatum
File:Striatum_transversal_sections.gif|Striatum
</gallery>

Revision as of 17:43, 18 February 2025


Striatum

The striatum is a subcortical part of the forebrain and a critical component of the basal ganglia system. It plays a significant role in various functions, including motor control, cognition, emotion, and reward. The striatum is divided into two main parts: the caudate nucleus and the putamen.

File:Basal ganglia and related structures.svg
Diagram of the basal ganglia, including the striatum.

Anatomy

The striatum is located deep within the cerebral hemispheres and is the largest component of the basal ganglia. It is primarily composed of two structures:

  • Caudate nucleus: This C-shaped structure is located adjacent to the lateral ventricles and is involved in various higher neurological functions, including learning and memory.
  • Putamen: Situated more laterally, the putamen is involved in regulating movements and influencing various types of learning.

The striatum is also functionally divided into the dorsal striatum and the ventral striatum. The dorsal striatum includes the caudate nucleus and putamen, while the ventral striatum includes the nucleus accumbens and the olfactory tubercle.

Function

The striatum is involved in multiple functions:

  • Motor control: The striatum receives input from the cerebral cortex and is involved in the planning and modulation of movement pathways.
  • Cognitive processes: It plays a role in various cognitive processes, including decision-making and executive functions.
  • Reward and reinforcement: The ventral striatum, particularly the nucleus accumbens, is crucial in the brain's reward system, influencing motivation and reinforcement learning.
  • Emotional regulation: The striatum is involved in processing emotions and is linked to various psychiatric disorders.

Clinical Significance

Dysfunction of the striatum is associated with several neurological and psychiatric disorders:

  • Parkinson's disease: Characterized by the degeneration of dopaminergic neurons that project to the striatum, leading to motor deficits.
  • Huntington's disease: A genetic disorder that causes the progressive breakdown of nerve cells in the striatum, leading to movement, cognitive, and psychiatric symptoms.
  • Obsessive-compulsive disorder (OCD): Involves abnormalities in the striatum and its connections, affecting behavior and thought patterns.
  • Addiction: The striatum is involved in the reward circuitry of the brain, and its dysfunction can contribute to addictive behaviors.

Related pages