ADB-FUBHQUCA: Difference between revisions

From WikiMD's Wellness Encyclopedia

CSV import
 
CSV import
 
Line 1: Line 1:
{{Short description|Synthetic cannabinoid}}
{{short description|Synthetic cannabinoid}}
{{Drugbox
{{DISPLAYTITLE:ADB-FUBHQUCA}}
| verifiedfields = changed
| verifiedrevid = 477002123
| IUPAC_name = N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide
| image = ADB-FUBHQUCA_structure.png
}}


'''ADB-FUBHQUCA''' is a synthetic cannabinoid that has been used in scientific research and is a designer drug. It is a potent agonist of the [[cannabinoid receptor]]s, which are part of the [[endocannabinoid system]].
==Overview==
'''ADB-FUBHQUCA''' is a synthetic cannabinoid that has been identified in various designer drug products. It is part of a class of compounds that are designed to mimic the effects of [[tetrahydrocannabinol]] (THC), the primary psychoactive component of [[cannabis]]. These substances are often referred to as "[[synthetic cannabinoids]]" and are commonly found in products marketed as "[[spice]]" or "[[K2]]".


==Chemical structure==
==Chemical Structure==
ADB-FUBHQUCA belongs to the indazole-3-carboxamide family of synthetic cannabinoids. Its chemical structure includes a 1-(4-fluorobenzyl) group attached to an indazole core, with an amide linkage to a tert-leucine moiety. The presence of the fluorobenzyl group is a common feature in many synthetic cannabinoids, contributing to their high affinity for cannabinoid receptors.
[[File:ADB-FUBHQUCA_structure.png|thumb|right|Chemical structure of ADB-FUBHQUCA]]
ADB-FUBHQUCA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 1-(4-fluorobenzyl)-1H-indazole-3-carboxamide core, which is a common feature among many synthetic cannabinoids. The presence of the fluorobenzyl group is thought to contribute to its high affinity for the [[cannabinoid receptor]]s.


==Pharmacology==
==Pharmacology==
As a synthetic cannabinoid, ADB-FUBHQUCA acts as a full agonist at the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] receptors. These receptors are part of the [[G protein-coupled receptor]] family and are primarily involved in the modulation of neurotransmitter release in the [[central nervous system]]. The activation of these receptors by ADB-FUBHQUCA can lead to effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].
Synthetic cannabinoids like ADB-FUBHQUCA act as agonists at the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] cannabinoid receptors in the [[central nervous system]]. These receptors are part of the [[endocannabinoid system]], which plays a role in regulating mood, memory, appetite, and pain sensation. The activation of these receptors by synthetic cannabinoids can lead to effects similar to those of THC, including euphoria, altered perception, and relaxation. However, synthetic cannabinoids can also cause severe adverse effects, such as [[tachycardia]], [[hypertension]], [[hallucinations]], and [[seizures]].


==Legal status==
==Legal Status==
The legal status of ADB-FUBHQUCA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is often included in legislation targeting synthetic cannabinoids and other [[designer drugs]].
The legal status of ADB-FUBHQUCA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies often place synthetic cannabinoids under temporary or permanent bans to prevent their distribution and use.


==Health effects==
==Health Risks==
The use of ADB-FUBHQUCA, like other synthetic cannabinoids, can lead to a range of adverse health effects. These may include [[tachycardia]], [[hypertension]], [[nausea]], [[vomiting]], [[anxiety]], and [[hallucinations]]. In severe cases, it can lead to [[seizures]], [[psychosis]], and [[renal failure]].
The use of synthetic cannabinoids like ADB-FUBHQUCA is associated with significant health risks. These compounds can be much more potent than natural THC, leading to a higher likelihood of overdose and severe side effects. Users may experience [[anxiety]], [[paranoia]], [[psychosis]], and [[cardiovascular complications]]. Long-term use can lead to [[addiction]] and withdrawal symptoms.
 
==Synthesis==
The synthesis of ADB-FUBHQUCA involves the reaction of 1-(4-fluorobenzyl)-1H-indazole-3-carboxylic acid with tert-leucine and subsequent conversion to the amide. This process requires careful control of reaction conditions to ensure the purity and yield of the final product.


==Related pages==
==Related pages==
* [[Synthetic cannabinoids]]
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor]]
* [[Designer drug]]
* [[Endocannabinoid system]]
* [[Endocannabinoid system]]
* [[Tetrahydrocannabinol]]
* [[Spice (drug)]]


[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Designer drugs]]
[[Category:Designer drugs]]
[[Category:Indazolecarboxamides]]

Latest revision as of 11:07, 15 February 2025

Synthetic cannabinoid



Overview[edit]

ADB-FUBHQUCA is a synthetic cannabinoid that has been identified in various designer drug products. It is part of a class of compounds that are designed to mimic the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis. These substances are often referred to as "synthetic cannabinoids" and are commonly found in products marketed as "spice" or "K2".

Chemical Structure[edit]

Chemical structure of ADB-FUBHQUCA

ADB-FUBHQUCA is chemically classified as an indazole-based synthetic cannabinoid. Its structure includes a 1-(4-fluorobenzyl)-1H-indazole-3-carboxamide core, which is a common feature among many synthetic cannabinoids. The presence of the fluorobenzyl group is thought to contribute to its high affinity for the cannabinoid receptors.

Pharmacology[edit]

Synthetic cannabinoids like ADB-FUBHQUCA act as agonists at the CB1 and CB2 cannabinoid receptors in the central nervous system. These receptors are part of the endocannabinoid system, which plays a role in regulating mood, memory, appetite, and pain sensation. The activation of these receptors by synthetic cannabinoids can lead to effects similar to those of THC, including euphoria, altered perception, and relaxation. However, synthetic cannabinoids can also cause severe adverse effects, such as tachycardia, hypertension, hallucinations, and seizures.

Legal Status[edit]

The legal status of ADB-FUBHQUCA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. Regulatory agencies often place synthetic cannabinoids under temporary or permanent bans to prevent their distribution and use.

Health Risks[edit]

The use of synthetic cannabinoids like ADB-FUBHQUCA is associated with significant health risks. These compounds can be much more potent than natural THC, leading to a higher likelihood of overdose and severe side effects. Users may experience anxiety, paranoia, psychosis, and cardiovascular complications. Long-term use can lead to addiction and withdrawal symptoms.

Related pages[edit]