DOC

DOC (2,5-Dimethoxy-4-chloroamphetamine) is a psychedelic drug and a substituted amphetamine. It is notably known for its psychological effects, which can include altered states of consciousness, visual disturbances, and profound changes in thought processes and mood.

Chemistry

DOC is a member of the DOx family of psychedelic amphetamines. Its chemical structure consists of a amphetamine backbone that is substituted at the alpha carbon with a methyl group, and at the 4 position of the benzene ring with a chlorine atom. Additionally, it has two methoxy groups attached at the 2 and 5 positions of the benzene ring. This molecular configuration is similar to other compounds in the DOx family, differing primarily in the substitution on the benzene ring.

Pharmacology

The pharmacological action of DOC is primarily through its activity as a serotonin receptor agonist. It is known to affect the 5-HT2A receptor, which is implicated in its psychedelic effects. The compound's effects are long-lasting, typically ranging from 12 to 24 hours, depending on the dose.

Effects

The effects of DOC are dose-dependent and can vary significantly among individuals. Users often report profound changes in perception, including visual and auditory hallucinations, enhanced emotional sensitivity, altered sense of time, and increased introspection. These effects make it popular among users of psychedelics for recreational and entheogenic purposes.

Risks and Safety

As with other powerful psychedelic substances, DOC carries risks of adverse psychological reactions such as anxiety, paranoia, and delusions. Due to its potent effects and long duration, there is a higher risk of experiencing intense and challenging trips or "bad trips." There is also potential for neurotoxic effects, although research on this aspect is limited.

Legal Status

The legal status of DOC varies by country, but it has been controlled in many jurisdictions due to concerns about its potential for abuse and harm. In some countries, it is listed as a controlled substance under various drug laws, making its possession, manufacture, and distribution illegal.

See Also

• Psychedelic therapy
• Designer drug
• Drug policy

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