1-Phenylethanol: Difference between revisions

Chemical Compound
	Identifiers
CAS Number
PubChem CID
ChemSpider ID
UNII
ChEBI
ChEMBL
	Properties
Chemical Formula
Molar Mass
Appearance
Density
Melting Point
Boiling Point
	Hazards
GHS Pictograms	[[File:\|50px]]
GHS Signal Word
GHS Hazard Statements
NFPA 704	[[File:\|50px]]
	References

Latest revision as of 06:20, 11 December 2024

An organic compound used in various applications

1-Phenylethanol is an organic compound with the chemical formula C₈H₁₀O. It is a secondary alcohol and is often used in the synthesis of other chemicals, as well as in the fragrance and flavor industries.

Structure and Properties[edit]

1-Phenylethanol consists of a phenyl group (C₆H₅) attached to a secondary alcohol group (CH(OH)CH₃). This structure makes it a chiral molecule, meaning it can exist in two enantiomeric forms: (R)-1-phenylethanol and (S)-1-phenylethanol. The presence of the hydroxyl group contributes to its alcohol properties, such as the ability to form hydrogen bonds.

Synthesis[edit]

1-Phenylethanol can be synthesized through several methods:

Reduction of Acetophenone: One common method is the reduction of acetophenone using reducing agents such as sodium borohydride or lithium aluminium hydride.
Grignard Reaction: Another method involves the reaction of phenylmagnesium bromide with formaldehyde, followed by hydrolysis.

Applications[edit]

1-Phenylethanol is used in various applications:

Fragrance Industry: It is used as a fragrance component due to its pleasant floral odor.
Flavor Industry: It is used as a flavoring agent in food products.
Chemical Synthesis: It serves as an intermediate in the synthesis of pharmaceuticals and other organic compounds.

Safety and Handling[edit]

1-Phenylethanol should be handled with care. It is slightly soluble in water and can cause irritation to the skin and eyes upon contact. Proper protective equipment, such as gloves and goggles, should be used when handling this chemical.

Also see[edit]

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-<br>== 1-Phenylethanol ==
+{{Short description|An organic compound used in various applications}}
+{{Chembox
+| Name = 1-Phenylethanol
+| ImageFile = 1-Phenylethanol.png
+| ImageSize = 200px
+| ImageAlt = Skeletal formula of 1-Phenylethanol
+| IUPACName = 1-Phenylethanol
+| OtherNames = α-Methylbenzyl alcohol
+| Section1 = {{Chembox Identifiers
+  | CASNo = 98-85-1
+  | PubChem = 7409
+  | ChemSpiderID = 7131
+  | UNII = 0F897O3O4M
+  | InChI = 1S/C8H10O/c1-7(9)8-5-3-2-4-6-8/h2-7,9H,1H3
+  | InChIKey = WAPNOHKVXSQRPX-UHFFFAOYSA-N
+  | SMILES = CC(C1=CC=CC=C1)O
+}}
+| Section2 = {{Chembox Properties
+  | C=8
+  | H=10
+  | O=1
+  | Appearance = Colorless liquid
+  | Density = 1.02 g/cm³
+  | MeltingPt = -15 °C
+  | BoilingPt = 204 °C
+  | Solubility = Slightly soluble in water
+}}
+}}
-'''1-Phenylethanol''' is an organic compound with the chemical formula C<sub>8</sub>H<sub>10</sub>O. It is a secondary alcohol consisting of a phenyl group attached to the second carbon of an ethanol chain. This compound is of interest in both academic research and industrial applications due to its role as an intermediate in the synthesis of various pharmaceuticals and fragrances.
+'''1-Phenylethanol''' is an [[organic compound]] with the chemical formula C₈H₁₀O. It is a secondary alcohol and is often used in the synthesis of other chemicals, as well as in the fragrance and flavor industries.
-=== Structure and Properties ===
+==Structure and Properties==
--Phenylethanol is characterized by the presence of a hydroxyl group (-OH) attached to a carbon atom that is also bonded to a phenyl group (C<sub>6</sub>H<sub>5</sub>) and a methyl group (CH<sub>3</sub>). This structure imparts certain physical and chemical properties to the compound:
+-Phenylethanol consists of a phenyl group (C₆H₅) attached to a secondary alcohol group (CH(OH)CH₃). This structure makes it a chiral molecule, meaning it can exist in two enantiomeric forms: (R)-1-phenylethanol and (S)-1-phenylethanol. The presence of the hydroxyl group contributes to its alcohol properties, such as the ability to form hydrogen bonds.
-* '''Molecular Weight:''' 122.16 g/mol
+==Synthesis==
-* '''Appearance:''' Colorless liquid
+-Phenylethanol can be synthesized through several methods:
-* '''Density:''' 1.02 g/cm<sup>3</sup>
-* '''Boiling Point:''' 204 °C (399 °F)
-* '''Solubility:''' Slightly soluble in water; soluble in organic solvents such as ethanol and ether.
-=== Synthesis ===
+* '''Reduction of Acetophenone''': One common method is the reduction of [[acetophenone]] using reducing agents such as [[sodium borohydride]] or [[lithium aluminium hydride]].
--Phenylethanol can be synthesized through several methods, including:
+* '''Grignard Reaction''': Another method involves the reaction of phenylmagnesium bromide with formaldehyde, followed by hydrolysis.
-* '''Reduction of Acetophenone:''' One common method involves the reduction of acetophenone using reducing agents such as sodium borohydride (NaBH<sub>4</sub>) or lithium aluminum hydride (LiAlH<sub>4</sub>). This reaction selectively reduces the carbonyl group to a hydroxyl group, yielding 1-phenylethanol.
+==Applications==
+-Phenylethanol is used in various applications:
-* '''Grignard Reaction:''' Another method involves the Grignard reaction, where phenylmagnesium bromide (C<sub>6</sub>H<sub>5</sub>MgBr) is reacted with formaldehyde, followed by hydrolysis to produce 1-phenylethanol.
+* '''Fragrance Industry''': It is used as a fragrance component due to its pleasant floral odor.
+* '''Flavor Industry''': It is used as a flavoring agent in food products.
+* '''Chemical Synthesis''': It serves as an intermediate in the synthesis of pharmaceuticals and other organic compounds.
-=== Applications ===
+==Safety and Handling==
--Phenylethanol is utilized in various applications due to its aromatic properties and reactivity:
+-Phenylethanol should be handled with care. It is slightly soluble in water and can cause irritation to the skin and eyes upon contact. Proper protective equipment, such as gloves and goggles, should be used when handling this chemical.
-* '''Fragrance Industry:''' It is used as a fragrance ingredient in perfumes and cosmetics due to its pleasant floral scent.
+==Also see==
+* [[Acetophenone]]
+* [[Benzyl alcohol]]
+* [[Phenethyl alcohol]]
+* [[Chirality (chemistry)]]
-* '''Pharmaceuticals:''' It serves as an intermediate in the synthesis of various pharmaceuticals, including analgesics and anti-inflammatory drugs.
+{{Organic-compound-stub}}
-* '''Chemical Synthesis:''' It is used as a chiral building block in the synthesis of more complex organic molecules.
-=== Safety and Handling ===
-While 1-phenylethanol is generally considered to be of low toxicity, it should be handled with care:
-* '''Hazards:''' It can cause irritation to the skin and eyes upon contact.
-* '''Precautions:''' Use appropriate personal protective equipment (PPE) such as gloves and goggles when handling the compound.
-* '''Storage:''' Store in a cool, dry place away from sources of ignition.
-=== Conclusion ===
--Phenylethanol is a versatile compound with significant importance in both industrial and research settings. Its role as an intermediate in the synthesis of fragrances and pharmaceuticals highlights its utility in various chemical processes. Understanding its properties and safe handling practices is essential for its effective use in laboratory and industrial applications.
 [[Category:Alcohols]]
 [[Category:Phenyl compounds]]
-[[Category:Organic chemistry]]
+[[Category:Secondary alcohols]]

Chemical Compound


Identifiers
CAS Number
PubChem CID
ChemSpider ID
UNII
ChEBI
ChEMBL
Properties
Chemical Formula
Molar Mass
Appearance
Density
Melting Point
Boiling Point
Hazards
GHS Pictograms	[[File:\|50px]]
GHS Signal Word
GHS Hazard Statements
NFPA 704	[[File:\|50px]]
References