Chlorophenylbiguanide

Chlorophenylbiguanide is a chemical compound that is often used in pharmacology and medicine for its various properties. It is a derivative of the biguanide class of drugs, which includes well-known medications such as metformin.

Chemical Structure

Chlorophenylbiguanide is composed of a chlorophenyl group attached to a biguanide molecule. The chlorophenyl group is a phenyl ring with a chlorine atom attached, while the biguanide molecule is a type of guanidine with two amino groups. The chemical formula for chlorophenylbiguanide is C13H16ClN5.

Pharmacological Properties

Chlorophenylbiguanide is known for its serotonin receptor agonist properties. It has a high affinity for the 5-HT3 receptor, a type of serotonin receptor found primarily in the brain and gastrointestinal tract. By activating these receptors, chlorophenylbiguanide can influence various physiological and psychological processes, including mood, appetite, and gut motility.

Medical Uses

While chlorophenylbiguanide is not typically used as a standalone medication, it is often used in research to study the effects of 5-HT3 receptor activation. It can also be used to induce vomiting in experimental animals, as activation of 5-HT3 receptors in the gut can stimulate the vomiting reflex.

Safety and Side Effects

As with any drug, chlorophenylbiguanide can have side effects. These can include nausea, vomiting, and diarrhea, which are likely due to its effects on the gastrointestinal tract. However, these side effects are generally mild and temporary.

See Also

• Biguanide
• Serotonin
• 5-HT3 receptor

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  Structure of Chlorophenylbiguanide