HOXB3: Difference between revisions
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== | {{Infobox gene | ||
| name = HOXB3 | |||
| symbol = HOXB3 | |||
| HGNCid = 5112 | |||
| chromosome = 17 | |||
| arm = q | |||
| band = 21.32 | |||
}} | |||
'''HOXB3''' is a [[gene]] that belongs to the [[homeobox]] family of [[transcription factors]]. These genes are critical in the regulation of [[developmental processes]] and are highly conserved across [[species]]. | |||
== Function == | == Function == | ||
The HOXB3 gene | The HOXB3 gene plays a significant role in the development of the [[central nervous system]], as well as in the formation of the [[skeletal system]]. It is involved in the [[patterning]] of the [[hindbrain]] and the [[spinal cord]]. The protein encoded by this gene acts as a [[transcription factor]] that binds to specific [[DNA]] sequences, thereby regulating the expression of other genes. | ||
== Clinical Significance == | == Clinical Significance == | ||
Mutations | Mutations or dysregulation of the HOXB3 gene can lead to developmental disorders. Research has shown that alterations in this gene may be associated with certain types of [[cancer]], including [[leukemia]] and [[breast cancer]]. Understanding the role of HOXB3 in these conditions can provide insights into potential therapeutic targets. | ||
== Research == | == Research == | ||
Studies on the HOXB3 gene continue to explore its function in [[embryonic development]] and its potential implications in [[oncology]]. Researchers are investigating how HOXB3 interacts with other [[homeobox genes]] and its role in [[gene regulatory networks]]. | |||
[[ | |||
== See Also == | == See Also == | ||
* [[Homeobox]] | * [[Homeobox]] | ||
* [[ | * [[Transcription factor]] | ||
* [[ | * [[Gene expression]] | ||
* [[ | * [[Developmental biology]] | ||
== References == | == References == | ||
<references /> | <references/> | ||
{{Gene-stub}} | |||
[[Category:Genes | [[Category:Genes on human chromosome 17]] | ||
[[Category:Transcription factors]] | [[Category:Transcription factors]] | ||
[[Category:Developmental | [[Category:Developmental genes and proteins]] | ||
Latest revision as of 20:34, 30 December 2024
| Symbol | HOXB3 |
|---|---|
| HGNC ID | 5112 |
| Alternative symbols | – |
| Entrez Gene | – |
| OMIM | – |
| RefSeq | – |
| UniProt | – |
| Chromosome | 17q21.32 |
| Locus supplementary data | – |
HOXB3 is a gene that belongs to the homeobox family of transcription factors. These genes are critical in the regulation of developmental processes and are highly conserved across species.
Function[edit]
The HOXB3 gene plays a significant role in the development of the central nervous system, as well as in the formation of the skeletal system. It is involved in the patterning of the hindbrain and the spinal cord. The protein encoded by this gene acts as a transcription factor that binds to specific DNA sequences, thereby regulating the expression of other genes.
Clinical Significance[edit]
Mutations or dysregulation of the HOXB3 gene can lead to developmental disorders. Research has shown that alterations in this gene may be associated with certain types of cancer, including leukemia and breast cancer. Understanding the role of HOXB3 in these conditions can provide insights into potential therapeutic targets.
Research[edit]
Studies on the HOXB3 gene continue to explore its function in embryonic development and its potential implications in oncology. Researchers are investigating how HOXB3 interacts with other homeobox genes and its role in gene regulatory networks.
See Also[edit]
References[edit]
<references/>
