THC morpholinylbutyrate: Difference between revisions

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'''THC Morpholinylbutyrate''' is a synthetic analogue of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]]. It is specifically a morpholinylbutyrate ester of THC, which differentiates it from the natural compound.
== THC Morpholinylbutyrate ==


==Chemistry==
[[File:THC_morpholinylbutyrate SP-111_structure.png|thumb|right|Chemical structure of THC Morpholinylbutyrate]]


THC Morpholinylbutyrate, also known as THC-M, is a synthetic derivative of THC, where a morpholinylbutyrate group is added to the THC molecule. This modification is believed to enhance the pharmacological properties of THC, although the exact mechanism is not fully understood.  
'''THC Morpholinylbutyrate''' is a synthetic derivative of [[tetrahydrocannabinol]] (THC), the principal psychoactive constituent of the [[cannabis]] plant. This compound is of interest in the field of [[pharmacology]] due to its potential therapeutic applications and its unique chemical properties.


==Pharmacology==
=== Chemical Structure ===


The pharmacological properties of THC Morpholinylbutyrate are similar to those of THC. It acts as a partial agonist at the [[CB1 receptor]] and [[CB2 receptor]], the two main cannabinoid receptors in the body. However, due to its synthetic nature and the addition of the morpholinylbutyrate group, it may have different pharmacokinetics and potentially enhanced potency or efficacy compared to THC.
THC Morpholinylbutyrate is characterized by the addition of a morpholinylbutyrate group to the THC molecule. This modification is designed to alter the pharmacokinetic properties of THC, potentially enhancing its [[bioavailability]] and [[metabolism|metabolic stability]]. The chemical structure of THC Morpholinylbutyrate is depicted in the image to the right.


==Medical Use==
=== Pharmacological Properties ===


The potential medical uses of THC Morpholinylbutyrate are similar to those of THC and other cannabinoids. These may include pain relief, anti-nausea, appetite stimulation, and potentially others. However, as a synthetic cannabinoid, it may also have unique properties or uses that are not shared by natural cannabinoids.
The pharmacological effects of THC Morpholinylbutyrate are similar to those of natural THC, including [[analgesic]], [[anti-inflammatory]], and [[psychoactive]] effects. However, the synthetic modification may result in differences in potency, duration of action, and side effect profile. Research is ongoing to determine the full spectrum of its pharmacological activity.


==Legal Status==
=== Therapeutic Applications ===


The legal status of THC Morpholinylbutyrate varies by country and region. In some places, it may be classified as a controlled substance due to its similarity to THC. In others, it may be legal for medical or research use.
Potential therapeutic applications of THC Morpholinylbutyrate include the treatment of [[chronic pain]], [[nausea]] and [[vomiting]] associated with [[chemotherapy]], and [[appetite stimulation]] in patients with [[cachexia]]. Its modified structure may offer advantages over natural THC in terms of reduced psychoactivity and improved therapeutic index.


==See Also==
=== Synthesis ===


* [[Cannabinoids]]
The synthesis of THC Morpholinylbutyrate involves the chemical modification of the THC molecule through the introduction of a morpholinylbutyrate moiety. This process requires expertise in [[organic chemistry]] and is typically conducted in a laboratory setting equipped for the handling of controlled substances.
* [[Synthetic cannabinoids]]
* [[CB1 receptor]]
* [[CB2 receptor]]


==References==
== Related Pages ==


<references />
* [[Tetrahydrocannabinol]]
* [[Cannabis]]
* [[Pharmacology]]
* [[Synthetic cannabinoids]]


[[Category:Pharmacology]]
[[Category:Pharmacology]]
[[Category:Cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
{{pharmacology-stub}}

Revision as of 06:40, 16 February 2025

THC Morpholinylbutyrate

File:THC morpholinylbutyrate SP-111 structure.png
Chemical structure of THC Morpholinylbutyrate

THC Morpholinylbutyrate is a synthetic derivative of tetrahydrocannabinol (THC), the principal psychoactive constituent of the cannabis plant. This compound is of interest in the field of pharmacology due to its potential therapeutic applications and its unique chemical properties.

Chemical Structure

THC Morpholinylbutyrate is characterized by the addition of a morpholinylbutyrate group to the THC molecule. This modification is designed to alter the pharmacokinetic properties of THC, potentially enhancing its bioavailability and metabolic stability. The chemical structure of THC Morpholinylbutyrate is depicted in the image to the right.

Pharmacological Properties

The pharmacological effects of THC Morpholinylbutyrate are similar to those of natural THC, including analgesic, anti-inflammatory, and psychoactive effects. However, the synthetic modification may result in differences in potency, duration of action, and side effect profile. Research is ongoing to determine the full spectrum of its pharmacological activity.

Therapeutic Applications

Potential therapeutic applications of THC Morpholinylbutyrate include the treatment of chronic pain, nausea and vomiting associated with chemotherapy, and appetite stimulation in patients with cachexia. Its modified structure may offer advantages over natural THC in terms of reduced psychoactivity and improved therapeutic index.

Synthesis

The synthesis of THC Morpholinylbutyrate involves the chemical modification of the THC molecule through the introduction of a morpholinylbutyrate moiety. This process requires expertise in organic chemistry and is typically conducted in a laboratory setting equipped for the handling of controlled substances.

Related Pages