Stanol ester: Difference between revisions

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'''Stanol ester''' is a type of [[ester]] that is formed when [[plant stanols]] are esterified with [[fatty acids]] of vegetable oils. Stanol esters are used in the food industry as a cholesterol-lowering ingredient. They are commonly found in [[margarine]]s, spreads, and other food products marketed to individuals who want to lower their [[blood cholesterol]] levels.
{{short description|A detailed overview of stanol esters}}


== History ==
==Stanol Esters==
[[File:Plantstanolester.svg|thumb|right|Chemical structure of a plant stanol ester]]
Stanol esters are a group of chemical compounds derived from [[plant stanols]], which are themselves hydrogenated forms of [[plant sterols]]. These compounds are known for their ability to lower [[cholesterol]] levels in the human body, making them a popular ingredient in functional foods aimed at improving cardiovascular health.


The use of stanol ester as a cholesterol-lowering agent was first discovered in the 1950s. However, it was not until the 1990s that stanol esters were commercially produced and marketed as a food ingredient. The first commercial product containing stanol ester was a margarine spread called [[Benecol]], which was launched in Finland in 1995.
==Chemical Structure==
Stanol esters are formed by the esterification of plant stanols with [[fatty acids]]. This process involves the chemical reaction between the hydroxyl group of the stanol and the carboxyl group of the fatty acid, resulting in the formation of an ester bond. The general structure of a stanol ester includes a sterol backbone with a saturated ring structure, which distinguishes it from its unsaturated sterol counterparts.


== Health Effects ==
==Sources and Production==
Stanol esters are typically derived from natural sources such as [[vegetable oils]] and [[wood pulp]]. The production process involves the extraction of plant sterols, followed by their hydrogenation to form stanols, and finally, the esterification with fatty acids. This process can be industrially scaled to produce stanol esters for use in various food products.


Stanol esters have been shown to lower blood cholesterol levels by inhibiting the absorption of dietary cholesterol in the [[small intestine]]. They do this by displacing cholesterol from the [[micelles]] that are necessary for the absorption of fats in the intestine. This results in a lower amount of cholesterol being absorbed into the body, and a higher amount being excreted.
==Health Benefits==
The primary health benefit of stanol esters is their ability to lower [[LDL cholesterol]] levels. They achieve this by inhibiting the absorption of cholesterol in the [[intestine]], which leads to a reduction in blood cholesterol levels. Regular consumption of foods enriched with stanol esters has been shown to contribute to the maintenance of normal blood cholesterol levels, thereby reducing the risk of [[cardiovascular disease]].


Several clinical studies have shown that consuming 2-3 grams of stanol esters per day can lower [[low-density lipoprotein]] (LDL) cholesterol levels by 10-15%. This can help to reduce the risk of [[coronary heart disease]].
==Applications in Food==
Stanol esters are commonly added to [[margarines]], [[yogurts]], and other dairy products. These functional foods are marketed towards individuals seeking to manage their cholesterol levels through dietary means. The incorporation of stanol esters into these products does not significantly alter their taste or texture, making them an attractive option for consumers.


== Safety and Side Effects ==
==Mechanism of Action==
The mechanism by which stanol esters lower cholesterol involves the competition with dietary and biliary cholesterol for incorporation into mixed micelles in the intestine. By reducing the amount of cholesterol that is absorbed, stanol esters effectively lower the total cholesterol levels in the bloodstream.


Stanol esters are generally considered safe for consumption. They have been approved for use as a food ingredient in many countries, including the United States and the European Union. However, some individuals may experience minor side effects such as gastrointestinal discomfort or loose stools.
==Safety and Regulation==
Stanol esters are generally recognized as safe (GRAS) by food safety authorities. However, it is recommended that their consumption be limited to the amounts found in fortified foods, as excessive intake may lead to gastrointestinal discomfort. Regulatory bodies such as the [[European Food Safety Authority]] (EFSA) and the [[U.S. Food and Drug Administration]] (FDA) have set guidelines for the use of stanol esters in food products.


== See Also ==
==Related pages==
 
* [[Plant sterol]]
* [[Phytosterols]]
* [[Cholesterol]]
* [[Cholesterol]]
* [[Coronary heart disease]]
* [[Cardiovascular disease]]
 
* [[Functional food]]
== References ==
 
<references />


[[Category:Food Ingredients]]
[[Category:Cholesterol lowering agents]]
[[Category:Cholesterol]]
[[Category:Food additives]]
[[Category:Coronary Heart Disease]]
{{Food-stub}}
{{Chemistry-stub}}

Latest revision as of 11:00, 15 February 2025

A detailed overview of stanol esters


Stanol Esters[edit]

File:Plantstanolester.svg
Chemical structure of a plant stanol ester

Stanol esters are a group of chemical compounds derived from plant stanols, which are themselves hydrogenated forms of plant sterols. These compounds are known for their ability to lower cholesterol levels in the human body, making them a popular ingredient in functional foods aimed at improving cardiovascular health.

Chemical Structure[edit]

Stanol esters are formed by the esterification of plant stanols with fatty acids. This process involves the chemical reaction between the hydroxyl group of the stanol and the carboxyl group of the fatty acid, resulting in the formation of an ester bond. The general structure of a stanol ester includes a sterol backbone with a saturated ring structure, which distinguishes it from its unsaturated sterol counterparts.

Sources and Production[edit]

Stanol esters are typically derived from natural sources such as vegetable oils and wood pulp. The production process involves the extraction of plant sterols, followed by their hydrogenation to form stanols, and finally, the esterification with fatty acids. This process can be industrially scaled to produce stanol esters for use in various food products.

Health Benefits[edit]

The primary health benefit of stanol esters is their ability to lower LDL cholesterol levels. They achieve this by inhibiting the absorption of cholesterol in the intestine, which leads to a reduction in blood cholesterol levels. Regular consumption of foods enriched with stanol esters has been shown to contribute to the maintenance of normal blood cholesterol levels, thereby reducing the risk of cardiovascular disease.

Applications in Food[edit]

Stanol esters are commonly added to margarines, yogurts, and other dairy products. These functional foods are marketed towards individuals seeking to manage their cholesterol levels through dietary means. The incorporation of stanol esters into these products does not significantly alter their taste or texture, making them an attractive option for consumers.

Mechanism of Action[edit]

The mechanism by which stanol esters lower cholesterol involves the competition with dietary and biliary cholesterol for incorporation into mixed micelles in the intestine. By reducing the amount of cholesterol that is absorbed, stanol esters effectively lower the total cholesterol levels in the bloodstream.

Safety and Regulation[edit]

Stanol esters are generally recognized as safe (GRAS) by food safety authorities. However, it is recommended that their consumption be limited to the amounts found in fortified foods, as excessive intake may lead to gastrointestinal discomfort. Regulatory bodies such as the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA) have set guidelines for the use of stanol esters in food products.

Related pages[edit]