Hispidulin

Hispidulin is a naturally occurring flavone, a type of flavonoid. It can be found in a variety of plants, including Salvia, Grindelia, Arrabidaea chica, and Chrysanthemum. Hispidulin has been studied for its potential health benefits, including its anti-inflammatory, anti-cancer, and neuroprotective effects.

Chemical Structure

Hispidulin is a flavone, a subclass of flavonoids. It is characterized by a 15-carbon skeleton, which consists of two phenyl groups and a heterocyclic ring. This carbon structure can be abbreviated C6-C3-C6. Hispidulin is also known as 4',5,7-trihydroxy-6-methoxyflavone.

Sources

Hispidulin can be found in several plants, including:

• Salvia: A genus of plants in the mint family, Lamiaceae.
• Grindelia: A genus of plants in the sunflower family, Asteraceae.
• Arrabidaea chica: A species of flowering plant in the family Bignoniaceae, native to South America.
• Chrysanthemum: A genus of flowering plants in the family Asteraceae, native to Asia and northeastern Europe.

Potential Health Benefits

Hispidulin has been studied for its potential health benefits. These include:

• Anti-inflammatory effects: Hispidulin may help reduce inflammation by inhibiting the production of pro-inflammatory cytokines.
• Anti-cancer effects: Hispidulin has been shown to inhibit the growth of certain types of cancer cells in laboratory studies.
• Neuroprotective effects: Hispidulin may help protect nerve cells from damage or degeneration.

See Also

• Flavonoid
• Phenyl group
• Cytokine
• Neuroprotection

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