O-2050: Difference between revisions

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'''O-2050''' is a synthetic cannabinoid that is used in scientific research. It is a selective agonist for the peripheral CB2 receptor, and has been used in a variety of studies to explore the role of this receptor in immune function, pain, and other physiological processes.
== O-2050 ==


==Chemistry==
[[File:O-2050_structure.png|thumb|right|Chemical structure of O-2050]]
O-2050 is a member of the [[naphthoylindole]] family of synthetic cannabinoids. It is structurally similar to other cannabinoids such as [[JWH-018]] and [[HU-210]], but differs in that it has a sulfonamide group, which is believed to be responsible for its selectivity for the CB2 receptor.


==Pharmacology==
'''O-2050''' is a synthetic cannabinoid that has been studied for its potential effects on the [[endocannabinoid system]]. It is a derivative of the well-known cannabinoid [[THC]] (tetrahydrocannabinol), which is the primary psychoactive component of [[Cannabis]]. O-2050 is of interest in research due to its unique properties and potential therapeutic applications.
O-2050 acts as a selective agonist for the CB2 receptor, with a [[Ki]] value of 23.4 nM. This makes it one of the most potent CB2-selective agonists currently known. It has been shown to produce anti-inflammatory effects in animal models, and has also been used to study the role of the CB2 receptor in pain perception.


==Research uses==
== Chemical Properties ==
Due to its selectivity for the CB2 receptor, O-2050 has been used in a variety of research studies. These have included investigations into the role of the CB2 receptor in immune function, the potential therapeutic uses of CB2 agonists in conditions such as [[chronic pain]] and [[inflammatory bowel disease]], and the effects of CB2 activation on [[neuroinflammation]] and [[neurodegeneration]].


==See also==
O-2050 is chemically classified as a [[cannabinoid]] and is structurally related to THC. The chemical structure of O-2050 includes modifications that differentiate it from naturally occurring cannabinoids, potentially altering its interaction with cannabinoid receptors.
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor type 2]]
* [[Synthetic cannabinoids]]


==References==
== Mechanism of Action ==
<references/>


[[Category:Cannabinoids]]
O-2050 primarily interacts with the [[cannabinoid receptor]]s, specifically [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] receptors, which are part of the [[endocannabinoid system]]. This system plays a crucial role in regulating various physiological processes, including [[pain]], [[appetite]], [[mood]], and [[memory]].
[[Category:Research chemicals]]
[[Category:CB2 agonists]]


{{stub}}
== Potential Applications ==
 
Research into O-2050 has suggested several potential applications:
 
* '''Pain Management''': Due to its interaction with cannabinoid receptors, O-2050 may have analgesic properties, making it a candidate for pain management therapies.
* '''Neurological Disorders''': The modulation of the endocannabinoid system by O-2050 could have implications for treating neurological disorders such as [[epilepsy]] and [[multiple sclerosis]].
* '''Anti-inflammatory Effects''': O-2050 may exhibit anti-inflammatory properties, which could be beneficial in treating conditions characterized by chronic inflammation.
 
== Safety and Efficacy ==
 
The safety and efficacy of O-2050 are still under investigation. As with many synthetic cannabinoids, there is a need for comprehensive studies to understand its pharmacokinetics, potential side effects, and long-term impact on human health.
 
== Legal Status ==
 
The legal status of O-2050 varies by jurisdiction. In some regions, it may be classified alongside other synthetic cannabinoids, which are often subject to strict regulations due to their potential for abuse and lack of clinical testing.
 
== Related Pages ==
 
* [[Cannabinoid]]
* [[Endocannabinoid system]]
* [[THC]]
* [[CB1 receptor]]
* [[CB2 receptor]]
 
[[Category:Synthetic cannabinoids]]

Latest revision as of 03:34, 13 February 2025

O-2050[edit]

Chemical structure of O-2050

O-2050 is a synthetic cannabinoid that has been studied for its potential effects on the endocannabinoid system. It is a derivative of the well-known cannabinoid THC (tetrahydrocannabinol), which is the primary psychoactive component of Cannabis. O-2050 is of interest in research due to its unique properties and potential therapeutic applications.

Chemical Properties[edit]

O-2050 is chemically classified as a cannabinoid and is structurally related to THC. The chemical structure of O-2050 includes modifications that differentiate it from naturally occurring cannabinoids, potentially altering its interaction with cannabinoid receptors.

Mechanism of Action[edit]

O-2050 primarily interacts with the cannabinoid receptors, specifically CB1 and CB2 receptors, which are part of the endocannabinoid system. This system plays a crucial role in regulating various physiological processes, including pain, appetite, mood, and memory.

Potential Applications[edit]

Research into O-2050 has suggested several potential applications:

  • Pain Management: Due to its interaction with cannabinoid receptors, O-2050 may have analgesic properties, making it a candidate for pain management therapies.
  • Neurological Disorders: The modulation of the endocannabinoid system by O-2050 could have implications for treating neurological disorders such as epilepsy and multiple sclerosis.
  • Anti-inflammatory Effects: O-2050 may exhibit anti-inflammatory properties, which could be beneficial in treating conditions characterized by chronic inflammation.

Safety and Efficacy[edit]

The safety and efficacy of O-2050 are still under investigation. As with many synthetic cannabinoids, there is a need for comprehensive studies to understand its pharmacokinetics, potential side effects, and long-term impact on human health.

Legal Status[edit]

The legal status of O-2050 varies by jurisdiction. In some regions, it may be classified alongside other synthetic cannabinoids, which are often subject to strict regulations due to their potential for abuse and lack of clinical testing.

Related Pages[edit]