Fibrosarcoma: Difference between revisions

Revision as of 11:32, 15 February 2025

A type of cancer that develops from fibrous connective tissue

Overview

Fibrosarcoma is a malignant tumor that arises from fibroblasts, the cells responsible for producing collagen and other fibers. It is a type of soft tissue sarcoma and can occur in any part of the body, although it is most commonly found in the extremities, trunk, and head and neck region.

Pathophysiology

Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The histological appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.

Clinical Presentation

Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the lungs and other organs.

Diagnosis

The diagnosis of fibrosarcoma is typically made through a combination of imaging studies and biopsy. Imaging techniques such as MRI and CT scan are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.

Treatment

The primary treatment for fibrosarcoma is surgical resection with wide margins to ensure complete removal of the tumor. In some cases, radiation therapy and/or chemotherapy may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.

Prognosis

The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.

Related pages

@@ Line 1: / Line 1: @@
-'''Fibrosarcoma''' is a type of [[tumor]] that originates in fibrous connective tissue. It is a rare form of [[cancer]], accounting for less than 1% of all adult cancers, but it is more common in children, where it accounts for approximately 5% of all soft tissue sarcomas.
+{{short description|A type of cancer that develops from fibrous connective tissue}}
+{{For|the condition in cats|Vaccine-associated sarcoma}}
-== Symptoms ==
+==Overview==
-The symptoms of fibrosarcoma can vary depending on the location of the tumor. Common symptoms include a noticeable lump or swelling, pain if the tumor is pressing on nerves or muscles, and fatigue.
+[[File:Cat_after_Fibrosarcom_op.jpg|thumb|right|A cat post-surgery for fibrosarcoma]]
+'''Fibrosarcoma''' is a malignant [[tumor]] that arises from [[fibroblasts]], the cells responsible for producing [[collagen]] and other fibers. It is a type of [[soft tissue sarcoma]] and can occur in any part of the body, although it is most commonly found in the [[extremities]], [[trunk]], and [[head and neck]] region.
-== Causes ==
+==Pathophysiology==
-The exact cause of fibrosarcoma is unknown. However, it is believed to be related to genetic mutations. Some cases have been associated with exposure to certain chemicals or radiation.
+Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The [[histological]] appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.
-== Diagnosis ==
+==Clinical Presentation==
-Diagnosis of fibrosarcoma typically involves a physical examination, imaging tests such as [[MRI]] or [[CT scan]], and a biopsy to examine the cells under a microscope.
+Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the [[lungs]] and other organs.
-== Treatment ==
+==Diagnosis==
-Treatment for fibrosarcoma usually involves surgery to remove the tumor. This may be followed by radiation therapy or chemotherapy to kill any remaining cancer cells. In some cases, targeted therapy or immunotherapy may be used.
+The diagnosis of fibrosarcoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. Imaging techniques such as [[MRI]] and [[CT scan]] are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.
-== Prognosis ==
+==Treatment==
-The prognosis for fibrosarcoma depends on a number of factors, including the size and location of the tumor, whether it has spread to other parts of the body, and the patient's overall health.
+The primary treatment for fibrosarcoma is [[surgical resection]] with wide margins to ensure complete removal of the tumor. In some cases, [[radiation therapy]] and/or [[chemotherapy]] may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.
-== See also ==
+==Prognosis==
-* [[Sarcoma]]
+The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.
-* [[Cancer]]
-* [[Chemotherapy]]
-* [[Radiation therapy]]
-[[Category:Cancer]]
+==Related pages==
-[[Category:Rare diseases]]
+* [[Soft tissue sarcoma]]
-[[Category:Pediatric cancers]]
+* [[Vaccine-associated sarcoma]]
+* [[Oncology]]
-{{stub}}
+[[Category:Oncology]]
+[[Category:Sarcoma]]