Botryomycosis

Botryomycosis is a rare, chronic, granulomatous, suppurative bacterial infection that primarily affects the skin and subcutaneous tissues. It is characterized by the formation of granules composed of bacterial masses, which are surrounded by eosinophilic material. The disease is caused by various bacteria, most commonly Staphylococcus aureus, but also Pseudomonas aeruginosa, Escherichia coli, Proteus species, and others.

Etiology

Botryomycosis is caused by various bacteria, most commonly Staphylococcus aureus, but also Pseudomonas aeruginosa, Escherichia coli, Proteus species, and others. The bacteria are usually part of the normal skin flora and gain entry into the body through minor trauma or surgical wounds.

Clinical Presentation

Botryomycosis usually presents as a slowly progressive, painless, indurated plaque with multiple draining sinuses. The sinuses discharge purulent material that contains yellow or white granules. The lesions can occur anywhere on the body but are most commonly found on the head, neck, and extremities.

Diagnosis

The diagnosis of botryomycosis is based on the clinical presentation and histopathological examination of the granules. The granules are composed of bacterial masses, which are surrounded by eosinophilic material. The bacteria can be identified by Gram staining and culture.

Treatment

The treatment of botryomycosis includes surgical debridement and long-term antibiotic therapy. The choice of antibiotic is based on the results of culture and sensitivity testing. The most commonly used antibiotics are penicillin, erythromycin, and tetracycline.

Prognosis

The prognosis of botryomycosis is generally good with appropriate treatment. However, the disease can be recurrent and may require multiple courses of treatment.

See Also

• Staphylococcus aureus
• Pseudomonas aeruginosa
• Escherichia coli
• Proteus

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