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| = Spondyloarthropathy =
| | #REDIRECT [[Spondyloarthritis]] |
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| [[File:Psoriatic arthritis spine ar1934-6.gif|alt=Psoriatic arthritis of the spine|thumb|Psoriatic arthritis of the spine]]
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| '''Spondyloarthropathy''' or '''spondyloarthrosis''' refers to a group of [[Joint disease|joint diseases]] that primarily affect the [[Vertebral column|vertebral column]]. These conditions are characterized by inflammation and can lead to significant pain and disability. They encompass a range of disorders, including but not limited to [[Psoriasis|psoriatic arthritis]], [[Ankylosing spondylitis]], and forms of [[Rheumatoid arthritis|rheumatoid arthritis]].
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| == Related terms ==
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| * [[spondylopathy]] is a disease of the vertebra
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| * Spondyloarthropathy with inflammation is called '''[[axial spondyloarthritis]]'''
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| == Signs and symptoms ==
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| Non-vertebral signs and symptoms is back pain which is unique because it decreases with activity.
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| ==Seronegative spondyloarthropathy==
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| ''Seronegative spondyloarthropathy'' (or ''seronegative spondyloarthritis'') is a group of diseases involving the [[axial skeleton]]
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| "Seronegative" refers to the fact that these diseases are negative for [[rheumatoid factor]]
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| == Types of Spondyloarthropathy ==
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| Spondyloarthropathies can be classified into several main types, each with distinct characteristics:
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| * '''Ankylosing Spondylitis''': A chronic inflammatory disease that primarily affects the spine and sacroiliac joints.
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| * '''Psoriatic Arthritis''': Associated with the skin condition psoriasis, this type can affect the spine in addition to other joints.
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| * '''Enteropathic Arthritis''': Arthritis that is associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
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| * '''Reactive Arthritis''': Arthritis that occurs as a reaction to an infection elsewhere in the body.
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| == Symptoms ==
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| Common symptoms of spondyloarthropathies include:
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| * Chronic back pain and stiffness, often worse in the morning or after periods of inactivity.
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| * Pain and swelling in other joints, depending on the specific type.
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| * In severe cases, a reduction in spinal flexibility and overall mobility.
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| == Diagnosis ==
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| Diagnosis of spondyloarthropathy involves:
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| * Clinical evaluation of symptoms.
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| * Imaging tests such as X-rays, MRI, and CT scans to detect changes in joints and bones.
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| * Blood tests to identify markers of inflammation and genetic markers associated with specific types.
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| == Treatment ==
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| Treatment for spondyloarthropathies aims to manage symptoms and prevent or slow disease progression. Options include:
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| * '''Medications''': Including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologics.
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| * '''Physical Therapy''': To maintain joint flexibility and muscle strength.
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| * '''Lifestyle Modifications''': Such as regular exercise and maintaining a healthy weight.
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| ==Conditions==
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| The following conditions are typically included within the group of ''seronegative spondylarthropathies'':
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| {|class="wikitable" | |
| ! Condition !! Percent of people with the <br>condition who are [[HLA-B27]] positive
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| | [[Axial spondyloarthritis]] (including [[ankylosing spondylitis]])<ref name="pmid11123073">{{cite journal |vauthors=Luong AA, Salonen DC |title=Imaging of the seronegative spondyloarthropathies |journal=Curr Rheumatol Rep |volume=2 |issue=4 |pages=288–96 |date=August 2000 |pmid=11123073 |doi= 10.1007/s11926-000-0065-z|url=}}</ref><ref name=agabegi2nd257>{{cite book |author1=Elizabeth D Agabegi |author2=Agabegi, Steven S. |title=Step-Up to Medicine (Step-Up Series) |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2008 |pages= |isbn=978-0-7817-7153-5 |oclc= |doi= |accessdate= |url-access=registration |url=https://archive.org/details/stepuptomedicine0000agab }}</ref>
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| *Caucasians: 92%<ref>[http://emedicine.medscape.com/article/332945-workup Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy Workup] Author: Lawrence H Brent. Chief Editor: Herbert S Diamond. Updated: Apr 19, 2011</ref>
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| *African-Americans: 50%
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| | [[Reactive arthritis]]<ref name="pmid11123073"/><ref name=agabegi2nd257/> (formerly known as Reiter's syndrome) || 60–80%
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| | [[Enteropathic arthropathy]] or spondylitis associated with<br>
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| [[inflammatory bowel disease]]<ref name="pmid11123073"/><ref name=agabegi2nd257/> (including [[Crohn's disease]] and [[ulcerative colitis]])
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| | 60%
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| |-
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| | [[Psoriatic arthritis]]<ref name="pmid11123073"/><ref name=agabegi2nd257/> || 40–50%
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| | Isolated acute [[anterior uveitis]] || 50%
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| | [[Juvenile idiopathic arthritis]] (subtype: late-onset oligoarticular JIA) ||
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| | [[Undifferentiated spondyloarthropathy]]<ref name="pmid11123073"/><ref name=agabegi2nd257/> (USpA) || 20–25%
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| |}
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| {{stub}}
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| {{Arthropathies and related conditions}}
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| {{Dorsopathies}}
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| == Prognosis ==
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| The prognosis for individuals with spondyloarthropathy varies depending on the type and severity of the condition. Early diagnosis and treatment are key to managing symptoms and maintaining quality of life.
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| [[Category:Musculoskeletal Disorders]]
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| [[Category:Rheumatology]]
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| {{DEFAULTSORT:Spondyloarthropathy}}
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| [[Category:Arthritis]]
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| [[Category:Musculoskeletal disorders]]
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