Duroziez's disease: Difference between revisions
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{{Infobox medical condition | |||
| name = Duroziez's disease | |||
| synonyms = [[Aortic regurgitation]] | |||
| specialty = [[Cardiology]] | |||
| symptoms = [[Shortness of breath]], [[fatigue]], [[palpitations]], [[chest pain]] | |||
| complications = [[Heart failure]], [[endocarditis]] | |||
| onset = Variable | |||
| duration = Chronic | |||
| causes = [[Rheumatic fever]], [[bicuspid aortic valve]], [[aortic root dilation]] | |||
| risks = [[Hypertension]], [[connective tissue disorders]] | |||
| diagnosis = [[Echocardiography]], [[cardiac MRI]], [[chest X-ray]] | |||
| differential = [[Mitral valve prolapse]], [[ventricular septal defect]] | |||
| treatment = [[Medications]], [[surgery]] | |||
| medication = [[Diuretics]], [[ACE inhibitors]], [[beta blockers]] | |||
| prognosis = Variable, depends on severity and treatment | |||
| frequency = Rare | |||
}} | |||
'''Duroziez's disease''' is a rare medical condition characterized by a specific type of [[aortic regurgitation]]. It is named after the French physician [[Paul Louis Duroziez]], who first described the condition in the 19th century. The disease is often associated with a distinctive murmur known as [[Duroziez's sign]], which can be heard over the femoral artery. | '''Duroziez's disease''' is a rare medical condition characterized by a specific type of [[aortic regurgitation]]. It is named after the French physician [[Paul Louis Duroziez]], who first described the condition in the 19th century. The disease is often associated with a distinctive murmur known as [[Duroziez's sign]], which can be heard over the femoral artery. | ||
== Pathophysiology == | == Pathophysiology == | ||
Duroziez's disease involves the improper closure of the [[aortic valve]], leading to the backflow of blood from the [[aorta]] into the [[left ventricle]] during [[diastole]]. This backflow increases the workload on the left ventricle, which can lead to [[left ventricular hypertrophy]] and eventually [[heart failure]] if left untreated. | Duroziez's disease involves the improper closure of the [[aortic valve]], leading to the backflow of blood from the [[aorta]] into the [[left ventricle]] during [[diastole]]. This backflow increases the workload on the left ventricle, which can lead to [[left ventricular hypertrophy]] and eventually [[heart failure]] if left untreated. | ||
== Clinical Features == | == Clinical Features == | ||
The hallmark of Duroziez's disease is the presence of Duroziez's sign, a double murmur heard over the femoral artery when it is compressed. Other symptoms may include: | The hallmark of Duroziez's disease is the presence of Duroziez's sign, a double murmur heard over the femoral artery when it is compressed. Other symptoms may include: | ||
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* [[Palpitations]] | * [[Palpitations]] | ||
* [[Angina]] (chest pain) | * [[Angina]] (chest pain) | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of Duroziez's disease is primarily clinical, based on the presence of Duroziez's sign and other symptoms of aortic regurgitation. [[Echocardiography]] is often used to confirm the diagnosis and assess the severity of the regurgitation. Additional diagnostic tools may include: | The diagnosis of Duroziez's disease is primarily clinical, based on the presence of Duroziez's sign and other symptoms of aortic regurgitation. [[Echocardiography]] is often used to confirm the diagnosis and assess the severity of the regurgitation. Additional diagnostic tools may include: | ||
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* [[Chest X-ray]] | * [[Chest X-ray]] | ||
* [[Cardiac MRI]] | * [[Cardiac MRI]] | ||
== Treatment == | == Treatment == | ||
The treatment of Duroziez's disease focuses on managing the symptoms and preventing complications. Medical management may include: | The treatment of Duroziez's disease focuses on managing the symptoms and preventing complications. Medical management may include: | ||
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* [[Vasodilators]] to decrease the workload on the heart | * [[Vasodilators]] to decrease the workload on the heart | ||
* [[Beta-blockers]] to control heart rate | * [[Beta-blockers]] to control heart rate | ||
In severe cases, surgical intervention such as [[aortic valve replacement]] may be necessary. | In severe cases, surgical intervention such as [[aortic valve replacement]] may be necessary. | ||
== Prognosis == | == Prognosis == | ||
The prognosis of Duroziez's disease varies depending on the severity of the aortic regurgitation and the patient's overall health. Early diagnosis and appropriate management are crucial for improving outcomes. | The prognosis of Duroziez's disease varies depending on the severity of the aortic regurgitation and the patient's overall health. Early diagnosis and appropriate management are crucial for improving outcomes. | ||
== See Also == | == See Also == | ||
* [[Aortic regurgitation]] | * [[Aortic regurgitation]] | ||
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* [[Heart failure]] | * [[Heart failure]] | ||
* [[Paul Louis Duroziez]] | * [[Paul Louis Duroziez]] | ||
== References == | == References == | ||
{{Reflist}} | {{Reflist}} | ||
== External Links == | == External Links == | ||
{{Commons category|Duroziez's disease}} | {{Commons category|Duroziez's disease}} | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Heart diseases]] | [[Category:Heart diseases]] | ||
{{Cardiology-stub}} | {{Cardiology-stub}} | ||
{{No image}} | {{No image}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 06:12, 4 April 2025
| Duroziez's disease | |
|---|---|
| Synonyms | Aortic regurgitation |
| Pronounce | N/A |
| Specialty | Cardiology |
| Symptoms | Shortness of breath, fatigue, palpitations, chest pain |
| Complications | Heart failure, endocarditis |
| Onset | Variable |
| Duration | Chronic |
| Types | N/A |
| Causes | Rheumatic fever, bicuspid aortic valve, aortic root dilation |
| Risks | Hypertension, connective tissue disorders |
| Diagnosis | Echocardiography, cardiac MRI, chest X-ray |
| Differential diagnosis | Mitral valve prolapse, ventricular septal defect |
| Prevention | N/A |
| Treatment | Medications, surgery |
| Medication | Diuretics, ACE inhibitors, beta blockers |
| Prognosis | Variable, depends on severity and treatment |
| Frequency | Rare |
| Deaths | N/A |
Duroziez's disease is a rare medical condition characterized by a specific type of aortic regurgitation. It is named after the French physician Paul Louis Duroziez, who first described the condition in the 19th century. The disease is often associated with a distinctive murmur known as Duroziez's sign, which can be heard over the femoral artery.
Pathophysiology[edit]
Duroziez's disease involves the improper closure of the aortic valve, leading to the backflow of blood from the aorta into the left ventricle during diastole. This backflow increases the workload on the left ventricle, which can lead to left ventricular hypertrophy and eventually heart failure if left untreated.
Clinical Features[edit]
The hallmark of Duroziez's disease is the presence of Duroziez's sign, a double murmur heard over the femoral artery when it is compressed. Other symptoms may include:
- Dyspnea (shortness of breath)
- Fatigue
- Palpitations
- Angina (chest pain)
Diagnosis[edit]
The diagnosis of Duroziez's disease is primarily clinical, based on the presence of Duroziez's sign and other symptoms of aortic regurgitation. Echocardiography is often used to confirm the diagnosis and assess the severity of the regurgitation. Additional diagnostic tools may include:
Treatment[edit]
The treatment of Duroziez's disease focuses on managing the symptoms and preventing complications. Medical management may include:
- Diuretics to reduce fluid overload
- Vasodilators to decrease the workload on the heart
- Beta-blockers to control heart rate
In severe cases, surgical intervention such as aortic valve replacement may be necessary.
Prognosis[edit]
The prognosis of Duroziez's disease varies depending on the severity of the aortic regurgitation and the patient's overall health. Early diagnosis and appropriate management are crucial for improving outcomes.
See Also[edit]
References[edit]
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External Links[edit]
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