Trichorrhexis invaginata: Difference between revisions
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{{Infobox medical condition | |||
| name = Trichorrhexis invaginata | |||
| synonyms = Bamboo hair | |||
| field = [[Dermatology]] | |||
| symptoms = [[Hair shaft]] deformity, [[brittle hair]] | |||
| complications = [[Hair breakage]] | |||
| onset = Childhood | |||
| duration = Lifelong | |||
| causes = [[Genetic disorder]] | |||
| risks = [[Netherton syndrome]] | |||
| diagnosis = [[Trichoscopy]], [[Light microscopy]] | |||
| differential = [[Trichorrhexis nodosa]], [[Monilethrix]] | |||
| treatment = [[Hair care]] | |||
| frequency = Rare | |||
}} | |||
'''Trichorrhexis invaginata''' is a rare genetic disorder that affects the hair shaft. It is also known as [[Bamboo hair]] due to the characteristic appearance of the hair under a microscope. The condition is often associated with [[Netherton syndrome]], a severe skin disorder. | '''Trichorrhexis invaginata''' is a rare genetic disorder that affects the hair shaft. It is also known as [[Bamboo hair]] due to the characteristic appearance of the hair under a microscope. The condition is often associated with [[Netherton syndrome]], a severe skin disorder. | ||
== Symptoms == | == Symptoms == | ||
The primary symptom of trichorrhexis invaginata is brittle hair that breaks easily. The hair may also appear dull and lackluster. In some cases, the condition may also cause slow hair growth or hair loss. | The primary symptom of trichorrhexis invaginata is brittle hair that breaks easily. The hair may also appear dull and lackluster. In some cases, the condition may also cause slow hair growth or hair loss. | ||
== Causes == | == Causes == | ||
Trichorrhexis invaginata is caused by mutations in the [[SPINK5]] gene. This gene provides instructions for making a protein called [[LEKTI]], which is involved in the growth and development of the skin and hair. Mutations in the SPINK5 gene disrupt the normal function of LEKTI, leading to the characteristic features of trichorrhexis invaginata. | Trichorrhexis invaginata is caused by mutations in the [[SPINK5]] gene. This gene provides instructions for making a protein called [[LEKTI]], which is involved in the growth and development of the skin and hair. Mutations in the SPINK5 gene disrupt the normal function of LEKTI, leading to the characteristic features of trichorrhexis invaginata. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of trichorrhexis invaginata is typically made through a detailed examination of the hair under a microscope. The hair shafts often have a distinctive "bamboo" appearance, with areas of normal thickness alternating with thinner, weaker sections. Genetic testing may also be performed to confirm the diagnosis. | Diagnosis of trichorrhexis invaginata is typically made through a detailed examination of the hair under a microscope. The hair shafts often have a distinctive "bamboo" appearance, with areas of normal thickness alternating with thinner, weaker sections. Genetic testing may also be performed to confirm the diagnosis. | ||
== Treatment == | == Treatment == | ||
There is currently no cure for trichorrhexis invaginata. Treatment is typically focused on managing the symptoms of the condition. This may include the use of special hair care products designed for brittle hair, as well as avoiding activities that can damage the hair, such as brushing or combing too vigorously. | There is currently no cure for trichorrhexis invaginata. Treatment is typically focused on managing the symptoms of the condition. This may include the use of special hair care products designed for brittle hair, as well as avoiding activities that can damage the hair, such as brushing or combing too vigorously. | ||
== See also == | == See also == | ||
* [[Netherton syndrome]] | * [[Netherton syndrome]] | ||
* [[Hair shaft disorders]] | * [[Hair shaft disorders]] | ||
* [[Genetic disorders]] | * [[Genetic disorders]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Hair disorders]] | [[Category:Hair disorders]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 05:58, 4 April 2025
| Trichorrhexis invaginata | |
|---|---|
| Synonyms | Bamboo hair |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Hair shaft deformity, brittle hair |
| Complications | Hair breakage |
| Onset | Childhood |
| Duration | Lifelong |
| Types | N/A |
| Causes | Genetic disorder |
| Risks | Netherton syndrome |
| Diagnosis | Trichoscopy, Light microscopy |
| Differential diagnosis | Trichorrhexis nodosa, Monilethrix |
| Prevention | N/A |
| Treatment | Hair care |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Trichorrhexis invaginata is a rare genetic disorder that affects the hair shaft. It is also known as Bamboo hair due to the characteristic appearance of the hair under a microscope. The condition is often associated with Netherton syndrome, a severe skin disorder.
Symptoms[edit]
The primary symptom of trichorrhexis invaginata is brittle hair that breaks easily. The hair may also appear dull and lackluster. In some cases, the condition may also cause slow hair growth or hair loss.
Causes[edit]
Trichorrhexis invaginata is caused by mutations in the SPINK5 gene. This gene provides instructions for making a protein called LEKTI, which is involved in the growth and development of the skin and hair. Mutations in the SPINK5 gene disrupt the normal function of LEKTI, leading to the characteristic features of trichorrhexis invaginata.
Diagnosis[edit]
Diagnosis of trichorrhexis invaginata is typically made through a detailed examination of the hair under a microscope. The hair shafts often have a distinctive "bamboo" appearance, with areas of normal thickness alternating with thinner, weaker sections. Genetic testing may also be performed to confirm the diagnosis.
Treatment[edit]
There is currently no cure for trichorrhexis invaginata. Treatment is typically focused on managing the symptoms of the condition. This may include the use of special hair care products designed for brittle hair, as well as avoiding activities that can damage the hair, such as brushing or combing too vigorously.
