Topical steroid withdrawal: Difference between revisions
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{{Infobox medical condition | |||
[[File:Red_(burning)_Skin_Syndrome_-_Showing_Face_Pattern_with_white_nose_sign_and_spared_palms_(soles_spared_too).jpg| | | name = Topical steroid withdrawal | ||
[[File:Red_(burning)_Skin_Syndrome_-_Typical_Pattern_of_Lower_Arms_&_Hands.jpg|thumb|Red (burning) Skin Syndrome - Typical Pattern of Lower Arms & Hands]] | | image = [[File:Red_(burning)_Skin_Syndrome_-_Showing_Face_Pattern_with_white_nose_sign_and_spared_palms_(soles_spared_too).jpg]] | ||
| caption = Red burning skin syndrome showing face pattern with white nose sign and spared palms | |||
| synonyms = Red skin syndrome, steroid dermatitis, steroid addiction | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Redness]], [[burning sensation]], [[itching]], [[peeling skin]], [[swelling]] | |||
| onset = After discontinuation of [[topical corticosteroids]] | |||
| duration = Weeks to months | |||
| causes = Prolonged use of topical corticosteroids | |||
| risks = Long-term use of potent topical steroids, sudden cessation | |||
| diagnosis = Clinical evaluation, history of steroid use | |||
| differential = [[Atopic dermatitis]], [[contact dermatitis]], [[psoriasis]] | |||
| treatment = Supportive care, [[moisturizers]], [[antihistamines]], [[pain management]] | |||
| prognosis = Generally good with time, but can be prolonged | |||
| frequency = Unknown, but considered rare | |||
}} | |||
[[File:Red_(burning)_Skin_Syndrome_-_Typical_Pattern_of_Lower_Arms_&_Hands.jpg|left|thumb|Red (burning) Skin Syndrome - Typical Pattern of Lower Arms & Hands]] | |||
'''Topical steroid withdrawal''' (TSW), also known as '''red skin syndrome''' or '''steroid dermatitis''' is a condition that can occur after the discontinuation of topical corticosteroids. These medications are commonly used to treat [[eczema]] and other inflammatory skin conditions. TSW is characterized by a range of symptoms including redness, burning, and peeling of the skin. | '''Topical steroid withdrawal''' (TSW), also known as '''red skin syndrome''' or '''steroid dermatitis''' is a condition that can occur after the discontinuation of topical corticosteroids. These medications are commonly used to treat [[eczema]] and other inflammatory skin conditions. TSW is characterized by a range of symptoms including redness, burning, and peeling of the skin. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of topical steroid withdrawal can vary but often include: | The symptoms of topical steroid withdrawal can vary but often include: | ||
* Intense [[erythema]] (redness) | * Intense [[erythema]] (redness) | ||
* Burning or stinging sensation | * Burning or stinging sensation | ||
| Line 16: | Line 27: | ||
* Itching | * Itching | ||
* Oozing or crusting | * Oozing or crusting | ||
These symptoms typically appear days to weeks after stopping the use of topical steroids and can last for weeks to months. | These symptoms typically appear days to weeks after stopping the use of topical steroids and can last for weeks to months. | ||
== Causes == | == Causes == | ||
Topical steroid withdrawal occurs when the skin becomes dependent on corticosteroids. Prolonged use of these medications can lead to [[tachyphylaxis]], where the skin becomes less responsive to the treatment, requiring higher doses for the same effect. When the steroids are stopped, the skin can react with a rebound effect, leading to the symptoms of TSW. | Topical steroid withdrawal occurs when the skin becomes dependent on corticosteroids. Prolonged use of these medications can lead to [[tachyphylaxis]], where the skin becomes less responsive to the treatment, requiring higher doses for the same effect. When the steroids are stopped, the skin can react with a rebound effect, leading to the symptoms of TSW. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of TSW is primarily clinical, based on the history of topical steroid use and the appearance of symptoms after discontinuation. There are no specific tests for TSW, but a dermatologist may rule out other conditions that could cause similar symptoms. | Diagnosis of TSW is primarily clinical, based on the history of topical steroid use and the appearance of symptoms after discontinuation. There are no specific tests for TSW, but a dermatologist may rule out other conditions that could cause similar symptoms. | ||
== Treatment == | == Treatment == | ||
The primary treatment for TSW is the cessation of topical steroids. Supportive care may include: | The primary treatment for TSW is the cessation of topical steroids. Supportive care may include: | ||
* Moisturizers to soothe the skin | * Moisturizers to soothe the skin | ||
* Cool compresses to reduce burning | * Cool compresses to reduce burning | ||
* Antihistamines to control itching | * Antihistamines to control itching | ||
* Pain relief medications | * Pain relief medications | ||
In some cases, systemic treatments such as [[immunosuppressants]] may be considered. | In some cases, systemic treatments such as [[immunosuppressants]] may be considered. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for individuals with TSW varies. While the condition can be distressing and uncomfortable, most people eventually recover with time. The duration of symptoms can range from a few months to over a year, depending on the severity of the withdrawal and the duration of prior steroid use. | The prognosis for individuals with TSW varies. While the condition can be distressing and uncomfortable, most people eventually recover with time. The duration of symptoms can range from a few months to over a year, depending on the severity of the withdrawal and the duration of prior steroid use. | ||
== See also == | |||
== | |||
* [[Eczema]] | * [[Eczema]] | ||
* [[Corticosteroid]] | * [[Corticosteroid]] | ||
* [[Dermatitis]] | * [[Dermatitis]] | ||
== References == | == References == | ||
{{Reflist}} | {{Reflist}} | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
Latest revision as of 14:32, 9 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Topical steroid withdrawal | |
|---|---|
| |
| Synonyms | Red skin syndrome, steroid dermatitis, steroid addiction |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Redness, burning sensation, itching, peeling skin, swelling |
| Complications | N/A |
| Onset | After discontinuation of topical corticosteroids |
| Duration | Weeks to months |
| Types | N/A |
| Causes | Prolonged use of topical corticosteroids |
| Risks | Long-term use of potent topical steroids, sudden cessation |
| Diagnosis | Clinical evaluation, history of steroid use |
| Differential diagnosis | Atopic dermatitis, contact dermatitis, psoriasis |
| Prevention | N/A |
| Treatment | Supportive care, moisturizers, antihistamines, pain management |
| Medication | N/A |
| Prognosis | Generally good with time, but can be prolonged |
| Frequency | Unknown, but considered rare |
| Deaths | N/A |

Topical steroid withdrawal (TSW), also known as red skin syndrome or steroid dermatitis is a condition that can occur after the discontinuation of topical corticosteroids. These medications are commonly used to treat eczema and other inflammatory skin conditions. TSW is characterized by a range of symptoms including redness, burning, and peeling of the skin.
Symptoms[edit]
The symptoms of topical steroid withdrawal can vary but often include:
- Intense erythema (redness)
- Burning or stinging sensation
- Peeling or shedding of the skin
- Swelling
- Itching
- Oozing or crusting
These symptoms typically appear days to weeks after stopping the use of topical steroids and can last for weeks to months.
Causes[edit]
Topical steroid withdrawal occurs when the skin becomes dependent on corticosteroids. Prolonged use of these medications can lead to tachyphylaxis, where the skin becomes less responsive to the treatment, requiring higher doses for the same effect. When the steroids are stopped, the skin can react with a rebound effect, leading to the symptoms of TSW.
Diagnosis[edit]
Diagnosis of TSW is primarily clinical, based on the history of topical steroid use and the appearance of symptoms after discontinuation. There are no specific tests for TSW, but a dermatologist may rule out other conditions that could cause similar symptoms.
Treatment[edit]
The primary treatment for TSW is the cessation of topical steroids. Supportive care may include:
- Moisturizers to soothe the skin
- Cool compresses to reduce burning
- Antihistamines to control itching
- Pain relief medications
In some cases, systemic treatments such as immunosuppressants may be considered.
Prognosis[edit]
The prognosis for individuals with TSW varies. While the condition can be distressing and uncomfortable, most people eventually recover with time. The duration of symptoms can range from a few months to over a year, depending on the severity of the withdrawal and the duration of prior steroid use.
See also[edit]
References[edit]
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