Pseudopolyps: Difference between revisions
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{{Infobox medical condition | |||
| name = Pseudopolyps | |||
| image = [[File:Chronic_Ulcerative_Colitis_1.jpg|left|thumb|Pseudopolyps in [[ulcerative colitis]]]] | |||
| caption = Pseudopolyps in [[ulcerative colitis]] | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Mucosal]] projections in the [[colon]] | |||
| complications = May be mistaken for [[colorectal cancer]] | |||
| onset = Associated with [[inflammatory bowel disease]] | |||
| duration = Chronic | |||
| causes = [[Ulcerative colitis]], [[Crohn's disease]] | |||
| risks = [[Inflammatory bowel disease]] | |||
| diagnosis = [[Colonoscopy]], [[endoscopy]] | |||
| differential = [[Colorectal cancer]], [[adenomatous polyps]] | |||
| treatment = Management of underlying [[inflammatory bowel disease]] | |||
| prognosis = Generally benign | |||
| frequency = Common in [[ulcerative colitis]] | |||
}} | |||
{{Short description|An overview of pseudopolyps in the context of inflammatory bowel disease}} | {{Short description|An overview of pseudopolyps in the context of inflammatory bowel disease}} | ||
==Pseudopolyps== | ==Pseudopolyps== | ||
[[File:Chronic_Ulcerative_Colitis_1.jpg|thumb | [[File:Chronic_Ulcerative_Colitis_1.jpg|left|thumb|Pseudopolyps in a patient with chronic ulcerative colitis]] | ||
Pseudopolyps are a type of polypoid lesion that can occur in the context of [[inflammatory bowel disease]] (IBD), particularly in [[ulcerative colitis]] and sometimes in [[Crohn's disease]]. They are not true polyps but rather represent areas of regenerating mucosa that appear polypoid due to the surrounding ulcerated tissue. | Pseudopolyps are a type of polypoid lesion that can occur in the context of [[inflammatory bowel disease]] (IBD), particularly in [[ulcerative colitis]] and sometimes in [[Crohn's disease]]. They are not true polyps but rather represent areas of regenerating mucosa that appear polypoid due to the surrounding ulcerated tissue. | ||
==Pathophysiology== | ==Pathophysiology== | ||
Pseudopolyps form as a result of repeated cycles of mucosal injury and healing. In conditions like ulcerative colitis, the mucosa becomes inflamed and ulcerated. During the healing process, the remaining islands of intact or regenerating mucosa can appear as raised lesions, which are termed pseudopolyps. These lesions are typically non-neoplastic and do not have malignant potential, unlike adenomatous polyps. | Pseudopolyps form as a result of repeated cycles of mucosal injury and healing. In conditions like ulcerative colitis, the mucosa becomes inflamed and ulcerated. During the healing process, the remaining islands of intact or regenerating mucosa can appear as raised lesions, which are termed pseudopolyps. These lesions are typically non-neoplastic and do not have malignant potential, unlike adenomatous polyps. | ||
==Clinical Significance== | ==Clinical Significance== | ||
Pseudopolyps are often seen during endoscopic examination of patients with ulcerative colitis. They can vary in size and number and are usually found in areas of the colon that have been affected by chronic inflammation. While pseudopolyps themselves are benign, their presence indicates a history of significant mucosal damage and inflammation. | Pseudopolyps are often seen during endoscopic examination of patients with ulcerative colitis. They can vary in size and number and are usually found in areas of the colon that have been affected by chronic inflammation. While pseudopolyps themselves are benign, their presence indicates a history of significant mucosal damage and inflammation. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of pseudopolyps is typically made during a colonoscopy, where they can be visually identified. Biopsies may be taken to confirm the diagnosis and to rule out dysplasia or malignancy, especially if the appearance is atypical. | The diagnosis of pseudopolyps is typically made during a colonoscopy, where they can be visually identified. Biopsies may be taken to confirm the diagnosis and to rule out dysplasia or malignancy, especially if the appearance is atypical. | ||
==Management== | ==Management== | ||
Management of pseudopolyps primarily involves treating the underlying inflammatory bowel disease. This may include the use of medications such as [[aminosalicylates]], [[corticosteroids]], [[immunomodulators]], and [[biologic agents]]. In some cases, surgical intervention may be necessary if there are complications such as obstruction or significant bleeding. | Management of pseudopolyps primarily involves treating the underlying inflammatory bowel disease. This may include the use of medications such as [[aminosalicylates]], [[corticosteroids]], [[immunomodulators]], and [[biologic agents]]. In some cases, surgical intervention may be necessary if there are complications such as obstruction or significant bleeding. | ||
==See also== | |||
== | |||
* [[Ulcerative colitis]] | * [[Ulcerative colitis]] | ||
* [[Crohn's disease]] | * [[Crohn's disease]] | ||
* [[Inflammatory bowel disease]] | * [[Inflammatory bowel disease]] | ||
* [[Colon polyp]] | * [[Colon polyp]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Inflammatory bowel disease]] | [[Category:Inflammatory bowel disease]] | ||
Latest revision as of 12:36, 12 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Pseudopolyps | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Mucosal projections in the colon |
| Complications | May be mistaken for colorectal cancer |
| Onset | Associated with inflammatory bowel disease |
| Duration | Chronic |
| Types | N/A |
| Causes | Ulcerative colitis, Crohn's disease |
| Risks | Inflammatory bowel disease |
| Diagnosis | Colonoscopy, endoscopy |
| Differential diagnosis | Colorectal cancer, adenomatous polyps |
| Prevention | N/A |
| Treatment | Management of underlying inflammatory bowel disease |
| Medication | N/A |
| Prognosis | Generally benign |
| Frequency | Common in ulcerative colitis |
| Deaths | N/A |
An overview of pseudopolyps in the context of inflammatory bowel disease
Pseudopolyps[edit]
Pseudopolyps are a type of polypoid lesion that can occur in the context of inflammatory bowel disease (IBD), particularly in ulcerative colitis and sometimes in Crohn's disease. They are not true polyps but rather represent areas of regenerating mucosa that appear polypoid due to the surrounding ulcerated tissue.
Pathophysiology[edit]
Pseudopolyps form as a result of repeated cycles of mucosal injury and healing. In conditions like ulcerative colitis, the mucosa becomes inflamed and ulcerated. During the healing process, the remaining islands of intact or regenerating mucosa can appear as raised lesions, which are termed pseudopolyps. These lesions are typically non-neoplastic and do not have malignant potential, unlike adenomatous polyps.
Clinical Significance[edit]
Pseudopolyps are often seen during endoscopic examination of patients with ulcerative colitis. They can vary in size and number and are usually found in areas of the colon that have been affected by chronic inflammation. While pseudopolyps themselves are benign, their presence indicates a history of significant mucosal damage and inflammation.
Diagnosis[edit]
The diagnosis of pseudopolyps is typically made during a colonoscopy, where they can be visually identified. Biopsies may be taken to confirm the diagnosis and to rule out dysplasia or malignancy, especially if the appearance is atypical.
Management[edit]
Management of pseudopolyps primarily involves treating the underlying inflammatory bowel disease. This may include the use of medications such as aminosalicylates, corticosteroids, immunomodulators, and biologic agents. In some cases, surgical intervention may be necessary if there are complications such as obstruction or significant bleeding.
