U-48800: Difference between revisions

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'''U-48800''' is a synthetic [[opioid]] that is part of the [[U-series drugs|U-series]] of opioids. It was first developed in the 1970s by a team at [[Upjohn]], a pharmaceutical company, which is reflected in the 'U' in its name. U-48800 is a structural analog of the earlier opioid [[AH-7921]] and has been sold as a [[designer drug]].
{{DISPLAYTITLE:U-48800}}


==Chemistry==
== Overview ==
U-48800 is a member of the [[drug class]] known as [[U-series drugs|U-series opioids]]. These drugs are characterized by a common backbone structure, which is modified to create different analogs. U-48800 is a structural analog of [[AH-7921]], meaning it shares a similar chemical structure but has been modified.  
'''U-48800''' is a synthetic opioid analgesic that is structurally related to [[U-47700]], a compound that was originally developed in the 1970s by the pharmaceutical company [[Upjohn]]. U-48800 is part of a class of drugs known as the [[benzamide]] opioids, which are known for their potent analgesic effects.


==Pharmacology==
== Chemical Structure ==
Like other opioids, U-48800 acts on the [[mu-opioid receptor]], producing effects such as analgesia, sedation, and euphoria. However, the exact mechanism of action and pharmacokinetics of U-48800 are not well understood, as it has not been extensively studied in humans.  
[[File:U-48800_structure.png|thumb|right|Chemical structure of U-48800]]
U-48800 has a chemical structure that is similar to other opioids in the benzamide class. The structure consists of a benzene ring attached to an amide group, with various substitutions that influence its pharmacological properties. The specific arrangement of atoms in U-48800 contributes to its high affinity for the [[mu-opioid receptor]], which is responsible for its analgesic effects.


==Effects==
== Pharmacology ==
The effects of U-48800 are similar to those of other opioids and include [[analgesia]], [[sedation]], [[euphoria]], and [[respiratory depression]]. However, due to its status as a designer drug and lack of clinical studies, the exact effects and safety profile of U-48800 are not well known.  
U-48800 acts primarily as a [[mu-opioid receptor]] agonist, which means it binds to and activates these receptors in the [[central nervous system]]. This action results in the inhibition of [[pain]] signals, leading to analgesia. Like other opioids, U-48800 can also produce [[euphoria]], [[sedation]], and [[respiratory depression]].


==Legal Status==
== Effects and Risks ==
U-48800 is a controlled substance in several countries, including the United States, where it is classified as a Schedule I drug under the [[Controlled Substances Act]]. This means it has a high potential for abuse and no accepted medical use.
The effects of U-48800 are similar to those of other potent opioids. Users may experience intense euphoria and pain relief, but these effects are accompanied by significant risks. The primary dangers associated with U-48800 use include respiratory depression, which can be fatal, and the potential for [[addiction]] and [[tolerance]].


==Health Risks==
== Legal Status ==
As with other opioids, U-48800 carries a risk of [[overdose]], which can result in respiratory depression, coma, and death. There have been several reported deaths associated with U-48800 use.  
Due to its potential for abuse and lack of medical use, U-48800 is classified as a controlled substance in many jurisdictions. The legal status of U-48800 varies by country, with some nations having specific regulations against its manufacture, distribution, and possession.


==See Also==
== Related Compounds ==
* [[U-47700]]
U-48800 is chemically related to several other synthetic opioids, including [[U-47700]], [[U-49900]], and [[AH-7921]]. These compounds share similar structures and pharmacological profiles, contributing to their classification as designer drugs.
* [[U-49900]]
* [[Fentanyl]]
* [[Opioid epidemic]]


==References==
== Related pages ==
<references />
* [[Opioid]]
* [[Mu-opioid receptor]]
* [[Synthetic opioid]]
* [[Benzamide]]


[[Category:Opioids]]
[[Category:Synthetic opioids]]
[[Category:Designer drugs]]
[[Category:Designer drugs]]
[[Category:Synthetic opioids]]
[[Category:U-series drugs]]
{{pharmacology-stub}}

Latest revision as of 10:50, 15 February 2025


Overview[edit]

U-48800 is a synthetic opioid analgesic that is structurally related to U-47700, a compound that was originally developed in the 1970s by the pharmaceutical company Upjohn. U-48800 is part of a class of drugs known as the benzamide opioids, which are known for their potent analgesic effects.

Chemical Structure[edit]

Chemical structure of U-48800

U-48800 has a chemical structure that is similar to other opioids in the benzamide class. The structure consists of a benzene ring attached to an amide group, with various substitutions that influence its pharmacological properties. The specific arrangement of atoms in U-48800 contributes to its high affinity for the mu-opioid receptor, which is responsible for its analgesic effects.

Pharmacology[edit]

U-48800 acts primarily as a mu-opioid receptor agonist, which means it binds to and activates these receptors in the central nervous system. This action results in the inhibition of pain signals, leading to analgesia. Like other opioids, U-48800 can also produce euphoria, sedation, and respiratory depression.

Effects and Risks[edit]

The effects of U-48800 are similar to those of other potent opioids. Users may experience intense euphoria and pain relief, but these effects are accompanied by significant risks. The primary dangers associated with U-48800 use include respiratory depression, which can be fatal, and the potential for addiction and tolerance.

Legal Status[edit]

Due to its potential for abuse and lack of medical use, U-48800 is classified as a controlled substance in many jurisdictions. The legal status of U-48800 varies by country, with some nations having specific regulations against its manufacture, distribution, and possession.

Related Compounds[edit]

U-48800 is chemically related to several other synthetic opioids, including U-47700, U-49900, and AH-7921. These compounds share similar structures and pharmacological profiles, contributing to their classification as designer drugs.

Related pages[edit]