Whipple's triad: Difference between revisions
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{{Infobox medical condition | |||
| name = Whipple's triad | |||
| synonyms = | |||
| field = [[Endocrinology]] | |||
| symptoms = [[Hypoglycemia]], [[neuroglycopenia]], relief of symptoms after [[glucose]] administration | |||
| complications = | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = [[Insulinoma]], [[insulin]] overdose, [[non-insulinoma pancreatogenous hypoglycemia syndrome]] (NIPHS) | |||
| risks = | |||
| diagnosis = Clinical evaluation, [[blood glucose]] measurement | |||
| differential = | |||
| prevention = | |||
| treatment = [[Glucose]] administration, treatment of underlying cause | |||
| medication = | |||
| prognosis = | |||
| frequency = | |||
| deaths = | |||
}} | |||
'''Whipple's triad''' is a collection of three criteria that suggest a patient's symptoms result from [[hypoglycemia]] caused by an [[insulinoma]], a type of [[pancreatic tumor]]. The triad was named after [[Allen Whipple]], an American surgeon who first described the condition in 1938. | '''Whipple's triad''' is a collection of three criteria that suggest a patient's symptoms result from [[hypoglycemia]] caused by an [[insulinoma]], a type of [[pancreatic tumor]]. The triad was named after [[Allen Whipple]], an American surgeon who first described the condition in 1938. | ||
==Criteria== | ==Criteria== | ||
The three criteria of Whipple's triad are: | The three criteria of Whipple's triad are: | ||
| Line 6: | Line 26: | ||
# Low plasma glucose at the time of symptoms | # Low plasma glucose at the time of symptoms | ||
# Relief of symptoms when glucose levels are raised | # Relief of symptoms when glucose levels are raised | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of hypoglycemia can vary from person to person, but often include: | Symptoms of hypoglycemia can vary from person to person, but often include: | ||
| Line 16: | Line 35: | ||
* [[Sweating]] | * [[Sweating]] | ||
* [[Tremor]] | * [[Tremor]] | ||
==Diagnosis== | ==Diagnosis== | ||
Whipple's triad is often used as a diagnostic tool in the evaluation of patients with suspected insulinoma. However, it is not definitive proof of the condition. Further tests, such as a [[fasting test]] or [[imaging studies]], may be required to confirm the diagnosis. | Whipple's triad is often used as a diagnostic tool in the evaluation of patients with suspected insulinoma. However, it is not definitive proof of the condition. Further tests, such as a [[fasting test]] or [[imaging studies]], may be required to confirm the diagnosis. | ||
==Treatment== | ==Treatment== | ||
Treatment for insulinoma typically involves surgical removal of the tumor. In some cases, medication may be used to manage symptoms until surgery can be performed. | Treatment for insulinoma typically involves surgical removal of the tumor. In some cases, medication may be used to manage symptoms until surgery can be performed. | ||
==See also== | ==See also== | ||
* [[Hypoglycemia]] | * [[Hypoglycemia]] | ||
| Line 28: | Line 44: | ||
* [[Pancreatic tumor]] | * [[Pancreatic tumor]] | ||
* [[Allen Whipple]] | * [[Allen Whipple]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
{{stub}} | {{stub}} | ||
[[Category:Medical terms]] | [[Category:Medical terms]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
{{No image}} | |||
Latest revision as of 06:11, 4 April 2025
| Whipple's triad | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Hypoglycemia, neuroglycopenia, relief of symptoms after glucose administration |
| Complications | |
| Onset | |
| Duration | |
| Types | |
| Causes | Insulinoma, insulin overdose, non-insulinoma pancreatogenous hypoglycemia syndrome (NIPHS) |
| Risks | |
| Diagnosis | Clinical evaluation, blood glucose measurement |
| Differential diagnosis | |
| Prevention | |
| Treatment | Glucose administration, treatment of underlying cause |
| Medication | |
| Prognosis | |
| Frequency | |
| Deaths | |
Whipple's triad is a collection of three criteria that suggest a patient's symptoms result from hypoglycemia caused by an insulinoma, a type of pancreatic tumor. The triad was named after Allen Whipple, an American surgeon who first described the condition in 1938.
Criteria[edit]
The three criteria of Whipple's triad are:
- Symptoms consistent with hypoglycemia
- Low plasma glucose at the time of symptoms
- Relief of symptoms when glucose levels are raised
Symptoms[edit]
Symptoms of hypoglycemia can vary from person to person, but often include:
Diagnosis[edit]
Whipple's triad is often used as a diagnostic tool in the evaluation of patients with suspected insulinoma. However, it is not definitive proof of the condition. Further tests, such as a fasting test or imaging studies, may be required to confirm the diagnosis.
Treatment[edit]
Treatment for insulinoma typically involves surgical removal of the tumor. In some cases, medication may be used to manage symptoms until surgery can be performed.
See also[edit]
References[edit]
<references />
