Lentigo maligna melanoma: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Lentigo maligna melanoma | |||
| image = [[File:Skin_Tumors-479.jpg|alt=Skin Tumors]] | |||
| caption = Lentigo maligna melanoma on the skin | |||
| field = [[Dermatology]], [[Oncology]] | |||
| synonyms = Hutchinson's melanotic freckle | |||
| symptoms = [[Skin lesion]], [[pigmented skin]], [[irregular borders]] | |||
| complications = [[Metastasis]], [[skin cancer]] | |||
| onset = Typically in older adults | |||
| duration = Chronic | |||
| types = [[Melanoma]] | |||
| causes = [[Ultraviolet radiation]], [[genetic factors]] | |||
| risks = [[Sun exposure]], [[fair skin]], [[age]] | |||
| diagnosis = [[Biopsy]], [[dermoscopy]] | |||
| differential = [[Seborrheic keratosis]], [[solar lentigo]], [[pigmented basal cell carcinoma]] | |||
| prevention = [[Sun protection]], [[regular skin checks]] | |||
| treatment = [[Surgical excision]], [[Mohs surgery]], [[radiation therapy]] | |||
| medication = [[Immunotherapy]], [[targeted therapy]] | |||
| prognosis = Generally good if detected early | |||
| frequency = Rare | |||
}} | |||
[[File:Lentigo_Maligna_Melanoma_Left_Central_Malar_Cheek.jpg|Lentigo Maligna Melanoma on the left central malar cheek|thumb|left]] | |||
'''Lentigo Maligna Melanoma''' ('''LMM''') is a type of [[melanoma]] that typically occurs in older adults, often in areas of the body that have been exposed to the sun. It is a slow-growing form of skin cancer that starts in cells called melanocytes, which produce the pigment (color) in your skin. | '''Lentigo Maligna Melanoma''' ('''LMM''') is a type of [[melanoma]] that typically occurs in older adults, often in areas of the body that have been exposed to the sun. It is a slow-growing form of skin cancer that starts in cells called melanocytes, which produce the pigment (color) in your skin. | ||
== Signs and Symptoms == | == Signs and Symptoms == | ||
The first sign of Lentigo Maligna Melanoma is often a patch of skin that looks like a freckle or age spot but gradually enlarges and changes color. The patch may be tan, brown, black, red, or white. It may also have an irregular border and different colors within it. | The first sign of Lentigo Maligna Melanoma is often a patch of skin that looks like a freckle or age spot but gradually enlarges and changes color. The patch may be tan, brown, black, red, or white. It may also have an irregular border and different colors within it. | ||
== Causes == | == Causes == | ||
Lentigo Maligna Melanoma is caused by changes (mutations) in the DNA of skin cells. These mutations cause the cells to grow out of control and form a mass of cancerous cells. The exact cause of these mutations is not known, but they are thought to be related to long-term exposure to ultraviolet (UV) radiation from the sun or tanning beds. | Lentigo Maligna Melanoma is caused by changes (mutations) in the DNA of skin cells. These mutations cause the cells to grow out of control and form a mass of cancerous cells. The exact cause of these mutations is not known, but they are thought to be related to long-term exposure to ultraviolet (UV) radiation from the sun or tanning beds. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of Lentigo Maligna Melanoma usually involves a skin biopsy, in which a small sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests or a sentinel lymph node biopsy, may be done to determine if the cancer has spread. | Diagnosis of Lentigo Maligna Melanoma usually involves a skin biopsy, in which a small sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests or a sentinel lymph node biopsy, may be done to determine if the cancer has spread. | ||
== Treatment == | == Treatment == | ||
Treatment for Lentigo Maligna Melanoma depends on the stage of the cancer and may include surgery, radiation therapy, immunotherapy, targeted therapy, or a combination of these. | Treatment for Lentigo Maligna Melanoma depends on the stage of the cancer and may include surgery, radiation therapy, immunotherapy, targeted therapy, or a combination of these. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for Lentigo Maligna Melanoma depends on several factors, including the stage of the cancer, the patient's overall health, and the response to treatment. | The prognosis for Lentigo Maligna Melanoma depends on several factors, including the stage of the cancer, the patient's overall health, and the response to treatment. | ||
== See Also == | == See Also == | ||
* [[Melanoma]] | * [[Melanoma]] | ||
| Line 22: | Line 39: | ||
* [[Radiation Therapy]] | * [[Radiation Therapy]] | ||
* [[Immunotherapy]] | * [[Immunotherapy]] | ||
[[Category:Skin Cancer]] | [[Category:Skin Cancer]] | ||
[[Category:Melanoma]] | [[Category:Melanoma]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 21:44, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Lentigo maligna melanoma | |
|---|---|
| |
| Synonyms | Hutchinson's melanotic freckle |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin lesion, pigmented skin, irregular borders |
| Complications | Metastasis, skin cancer |
| Onset | Typically in older adults |
| Duration | Chronic |
| Types | Melanoma |
| Causes | Ultraviolet radiation, genetic factors |
| Risks | Sun exposure, fair skin, age |
| Diagnosis | Biopsy, dermoscopy |
| Differential diagnosis | Seborrheic keratosis, solar lentigo, pigmented basal cell carcinoma |
| Prevention | Sun protection, regular skin checks |
| Treatment | Surgical excision, Mohs surgery, radiation therapy |
| Medication | Immunotherapy, targeted therapy |
| Prognosis | Generally good if detected early |
| Frequency | Rare |
| Deaths | N/A |
Lentigo Maligna Melanoma (LMM) is a type of melanoma that typically occurs in older adults, often in areas of the body that have been exposed to the sun. It is a slow-growing form of skin cancer that starts in cells called melanocytes, which produce the pigment (color) in your skin.
Signs and Symptoms[edit]
The first sign of Lentigo Maligna Melanoma is often a patch of skin that looks like a freckle or age spot but gradually enlarges and changes color. The patch may be tan, brown, black, red, or white. It may also have an irregular border and different colors within it.
Causes[edit]
Lentigo Maligna Melanoma is caused by changes (mutations) in the DNA of skin cells. These mutations cause the cells to grow out of control and form a mass of cancerous cells. The exact cause of these mutations is not known, but they are thought to be related to long-term exposure to ultraviolet (UV) radiation from the sun or tanning beds.
Diagnosis[edit]
Diagnosis of Lentigo Maligna Melanoma usually involves a skin biopsy, in which a small sample of the suspicious skin is removed and examined under a microscope. Other tests, such as imaging tests or a sentinel lymph node biopsy, may be done to determine if the cancer has spread.
Treatment[edit]
Treatment for Lentigo Maligna Melanoma depends on the stage of the cancer and may include surgery, radiation therapy, immunotherapy, targeted therapy, or a combination of these.
Prognosis[edit]
The prognosis for Lentigo Maligna Melanoma depends on several factors, including the stage of the cancer, the patient's overall health, and the response to treatment.
