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Latest revision as of 17:16, 22 March 2025
Huntington's disease (HD), also known as Huntington's chorea, is a genetic disorder that results in the death of brain cells. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unsteady gait often follow. As the disease advances, uncoordinated, jerky body movements become more apparent. Physical abilities gradually worsen until coordinated movement becomes difficult and the person is unable to talk. Mental abilities generally decline into dementia.
Causes[edit]
Huntington's disease is caused by an inherited defect in a single gene. HD is an autosomal dominant disorder, which means that a person needs only one copy of the defective gene to develop the disorder.
Symptoms[edit]
The symptoms of Huntington's disease can include cognitive decline, motor control problems, and various psychiatric symptoms.
Diagnosis[edit]
The diagnosis of Huntington's disease is based on the symptoms and signs in a person after a thorough examination and medical history. Genetic testing can provide a definitive diagnosis of HD.
Treatment[edit]
There is no cure for Huntington's disease, but there are treatments available to help manage symptoms. Medications are used to manage symptoms of movement problems, mental health conditions and other medical problems that may arise.
Prognosis[edit]
The progression of Huntington's disease varies from person to person. The disease may progress slowly for some people and more rapidly for others. The average lifespan after onset is around 10 to 20 years.
See also[edit]
References[edit]
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