Perifollicular fibroma: Difference between revisions

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'''Perifollicular fibroma''' is a rare, benign skin tumor that originates from the hair follicle. It is characterized by the presence of a solitary, small, firm, skin-colored papule. The lesion is usually asymptomatic, but it can sometimes cause discomfort or tenderness. The exact cause of perifollicular fibroma is unknown, but it is believed to be related to genetic factors.
{{SI}}
 
{{Infobox medical condition
| name            = Perifollicular fibroma
| image          = [[File:SkinTumors-P6050211.JPG|left|thumb|Perifollicular fibroma]]
| caption        = Perifollicular fibroma on the skin
| field          = [[Dermatology]]
| synonyms        =
| symptoms        = Small, firm, skin-colored papules
| complications  =
| onset          =
| duration        =
| causes          = Unknown
| risks          =
| diagnosis      = [[Skin biopsy]]
| differential    = [[Trichodiscoma]], [[Fibrous papule of the nose]], [[Angiofibroma]]
| prevention      =
| treatment      = [[Surgical excision]], [[Laser therapy]]
| medication      =
| prognosis      = Excellent
| frequency      = Rare
}}
'''Perifollicular fibroma''' is a benign [[skin tumor]] that arises from the connective tissue surrounding a [[hair follicle]]. It is considered a type of [[fibroma]], which is a tumor composed mainly of fibrous or connective tissue.
== Clinical Presentation ==
== Clinical Presentation ==
 
Perifollicular fibromas typically present as small, firm, skin-colored papules. They are most commonly found on the face, neck, and upper trunk. These lesions are usually asymptomatic and are often discovered incidentally during a routine skin examination.
Patients with perifollicular fibroma typically present with a solitary, small, firm, skin-colored papule. The lesion is usually located on the face, neck, or upper trunk. It is usually asymptomatic, but it can sometimes cause discomfort or tenderness. The lesion is usually less than 1 cm in diameter, but larger lesions have been reported.
== Pathophysiology ==
 
The exact cause of perifollicular fibroma is not well understood. It is thought to originate from the perifollicular connective tissue, which is the tissue surrounding the [[hair follicle]]. The tumor is composed of fibroblasts and collagen fibers, which are the main components of connective tissue.
== Diagnosis ==
== Diagnosis ==
 
Diagnosis of perifollicular fibroma is primarily clinical, based on the appearance of the lesion. However, a [[skin biopsy]] may be performed to confirm the diagnosis. Histologically, perifollicular fibromas show a proliferation of fibroblasts and collagen fibers around a central hair follicle.
The diagnosis of perifollicular fibroma is usually made based on the clinical presentation and histopathological examination. The histopathological features of perifollicular fibroma include a well-circumscribed dermal nodule composed of dense collagen bundles that surround and entraps hair follicles. The overlying epidermis is usually normal.
 
== Treatment ==
== Treatment ==
 
Treatment is usually not necessary for perifollicular fibromas, as they are benign and asymptomatic. However, if the lesion is cosmetically concerning or if there is uncertainty about the diagnosis, it can be removed surgically. Options for removal include [[excision]], [[shave biopsy]], or [[laser therapy]].
The treatment of perifollicular fibroma usually involves surgical excision. The prognosis is excellent, as the lesion is benign and does not recur after complete excision.
== Differential Diagnosis ==
 
The differential diagnosis for perifollicular fibroma includes other benign skin lesions such as [[dermatofibroma]], [[trichofolliculoma]], and [[angiofibroma]]. It is important to distinguish perifollicular fibroma from these other conditions to ensure appropriate management.
== See Also ==
== See also ==
 
* [[Fibroma]]
* [[Dermatology]]
* [[Skin tumor]]
* [[Skin tumor]]
* [[Hair follicle]]
* [[Hair follicle]]
* [[Benign tumor]]
* [[Dermatofibroma]]
* [[Surgical excision]]
 
== References ==
 
# Weedon D. Skin Pathology. 2nd ed. London: Churchill Livingstone; 2002.
# LeBoit PE, Burg G, Weedon D, Sarasain A. World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours. Lyon: IARC Press; 2006.
 
[[Category:Medicine]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Skin conditions]]
[[Category:Benign tumors]]
[[Category:Tumors]]
 
{{stub}}

Latest revision as of 15:57, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
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Perifollicular fibroma
Perifollicular fibroma
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Small, firm, skin-colored papules
Complications
Onset
Duration
Types N/A
Causes Unknown
Risks
Diagnosis Skin biopsy
Differential diagnosis Trichodiscoma, Fibrous papule of the nose, Angiofibroma
Prevention
Treatment Surgical excision, Laser therapy
Medication
Prognosis Excellent
Frequency Rare
Deaths N/A


Perifollicular fibroma is a benign skin tumor that arises from the connective tissue surrounding a hair follicle. It is considered a type of fibroma, which is a tumor composed mainly of fibrous or connective tissue.

Clinical Presentation[edit]

Perifollicular fibromas typically present as small, firm, skin-colored papules. They are most commonly found on the face, neck, and upper trunk. These lesions are usually asymptomatic and are often discovered incidentally during a routine skin examination.

Pathophysiology[edit]

The exact cause of perifollicular fibroma is not well understood. It is thought to originate from the perifollicular connective tissue, which is the tissue surrounding the hair follicle. The tumor is composed of fibroblasts and collagen fibers, which are the main components of connective tissue.

Diagnosis[edit]

Diagnosis of perifollicular fibroma is primarily clinical, based on the appearance of the lesion. However, a skin biopsy may be performed to confirm the diagnosis. Histologically, perifollicular fibromas show a proliferation of fibroblasts and collagen fibers around a central hair follicle.

Treatment[edit]

Treatment is usually not necessary for perifollicular fibromas, as they are benign and asymptomatic. However, if the lesion is cosmetically concerning or if there is uncertainty about the diagnosis, it can be removed surgically. Options for removal include excision, shave biopsy, or laser therapy.

Differential Diagnosis[edit]

The differential diagnosis for perifollicular fibroma includes other benign skin lesions such as dermatofibroma, trichofolliculoma, and angiofibroma. It is important to distinguish perifollicular fibroma from these other conditions to ensure appropriate management.

See also[edit]