Lobomycosis: Difference between revisions
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{{Infobox medical condition | |||
| name = Lobomycosis | |||
| image = [[File:Lobomycosis.jpg|left|thumb|Lobomycosis on the arm]] | |||
| caption = Lobomycosis on the arm | |||
| synonyms = [[Jorge Lobo's disease]], [[Keloidal blastomycosis]], [[Lacaziosis]] | |||
| pronunciation = | |||
| specialty = [[Infectious disease]] | |||
| symptoms = [[Keloid]]-like nodules, [[plaques]], [[ulceration]] | |||
| complications = [[Secondary infection]], [[disfigurement]] | |||
| onset = Gradual | |||
| duration = Chronic | |||
| causes = [[Lacazia loboi]] | |||
| risks = [[Tropical]] and [[subtropical]] climates, [[Amazon rainforest]] | |||
| diagnosis = [[Skin biopsy]], [[histopathology]] | |||
| differential = [[Leprosy]], [[Cutaneous leishmaniasis]], [[Chromoblastomycosis]] | |||
| prevention = Avoidance of [[trauma]] in endemic areas | |||
| treatment = [[Surgical excision]], [[antifungal]] therapy | |||
| medication = [[Clofazimine]], [[Itraconazole]] | |||
| prognosis = Variable, often chronic | |||
| frequency = Rare | |||
}} | |||
[[File:Lobomycosis-fungus-lesions.jpg|thumb|left]] | |||
'''Lobomycosis''' (also known as '''Lobo's disease''') is a rare fungal infection that primarily affects the skin and subcutaneous tissues. It is caused by the fungus ''[[Lacazia loboi]]'', which is found in tropical and subtropical regions, particularly in Central and South America. | '''Lobomycosis''' (also known as '''Lobo's disease''') is a rare fungal infection that primarily affects the skin and subcutaneous tissues. It is caused by the fungus ''[[Lacazia loboi]]'', which is found in tropical and subtropical regions, particularly in Central and South America. | ||
==Etiology== | ==Etiology== | ||
Lobomycosis is caused by the fungus ''[[Lacazia loboi]]''. This fungus is not found in the environment, but is believed to be transmitted through direct contact with an infected individual or animal, particularly dolphins. | Lobomycosis is caused by the fungus ''[[Lacazia loboi]]''. This fungus is not found in the environment, but is believed to be transmitted through direct contact with an infected individual or animal, particularly dolphins. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
The disease typically presents as keloid-like nodules on the skin, which can coalesce to form plaques. These lesions are usually found on exposed areas of the body, such as the face, ears, and extremities. The disease is chronic and progressive, and can lead to significant disfigurement if left untreated. | The disease typically presents as keloid-like nodules on the skin, which can coalesce to form plaques. These lesions are usually found on exposed areas of the body, such as the face, ears, and extremities. The disease is chronic and progressive, and can lead to significant disfigurement if left untreated. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of lobomycosis is based on clinical presentation and histopathological examination of skin biopsy specimens. The fungus ''[[Lacazia loboi]]'' can be seen in tissue sections as yeast-like cells arranged in chains or clusters. | Diagnosis of lobomycosis is based on clinical presentation and histopathological examination of skin biopsy specimens. The fungus ''[[Lacazia loboi]]'' can be seen in tissue sections as yeast-like cells arranged in chains or clusters. | ||
==Treatment== | ==Treatment== | ||
Treatment of lobomycosis is challenging due to the fungus's resistance to most antifungal drugs. Surgical excision of the lesions is often the treatment of choice. In some cases, antifungal drugs such as itraconazole or clofazimine may be used. | Treatment of lobomycosis is challenging due to the fungus's resistance to most antifungal drugs. Surgical excision of the lesions is often the treatment of choice. In some cases, antifungal drugs such as itraconazole or clofazimine may be used. | ||
==Epidemiology== | ==Epidemiology== | ||
Lobomycosis is endemic in certain regions of Central and South America, particularly in the Amazon basin. It is also seen in dolphins, which are believed to be a reservoir for the disease. | Lobomycosis is endemic in certain regions of Central and South America, particularly in the Amazon basin. It is also seen in dolphins, which are believed to be a reservoir for the disease. | ||
==See Also== | ==See Also== | ||
* [[Mycosis]] | * [[Mycosis]] | ||
* [[Tropical medicine]] | * [[Tropical medicine]] | ||
* [[Dermatology]] | * [[Dermatology]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
[[Category:Diseases and disorders]] | [[Category:Diseases and disorders]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Mycosis]] | [[Category:Mycosis]] | ||
[[Category:Tropical medicine]] | [[Category:Tropical medicine]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 04:24, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Lobomycosis | |
|---|---|
 | |
| Synonyms | Jorge Lobo's disease, Keloidal blastomycosis, Lacaziosis |
| Pronounce | N/A |
| Specialty | Infectious disease |
| Symptoms | Keloid-like nodules, plaques, ulceration |
| Complications | Secondary infection, disfigurement |
| Onset | Gradual |
| Duration | Chronic |
| Types | N/A |
| Causes | Lacazia loboi |
| Risks | Tropical and subtropical climates, Amazon rainforest |
| Diagnosis | Skin biopsy, histopathology |
| Differential diagnosis | Leprosy, Cutaneous leishmaniasis, Chromoblastomycosis |
| Prevention | Avoidance of trauma in endemic areas |
| Treatment | Surgical excision, antifungal therapy |
| Medication | Clofazimine, Itraconazole |
| Prognosis | Variable, often chronic |
| Frequency | Rare |
| Deaths | N/A |
Lobomycosis (also known as Lobo's disease) is a rare fungal infection that primarily affects the skin and subcutaneous tissues. It is caused by the fungus Lacazia loboi, which is found in tropical and subtropical regions, particularly in Central and South America.
Etiology[edit]
Lobomycosis is caused by the fungus Lacazia loboi. This fungus is not found in the environment, but is believed to be transmitted through direct contact with an infected individual or animal, particularly dolphins.
Clinical Presentation[edit]
The disease typically presents as keloid-like nodules on the skin, which can coalesce to form plaques. These lesions are usually found on exposed areas of the body, such as the face, ears, and extremities. The disease is chronic and progressive, and can lead to significant disfigurement if left untreated.
Diagnosis[edit]
Diagnosis of lobomycosis is based on clinical presentation and histopathological examination of skin biopsy specimens. The fungus Lacazia loboi can be seen in tissue sections as yeast-like cells arranged in chains or clusters.
Treatment[edit]
Treatment of lobomycosis is challenging due to the fungus's resistance to most antifungal drugs. Surgical excision of the lesions is often the treatment of choice. In some cases, antifungal drugs such as itraconazole or clofazimine may be used.
Epidemiology[edit]
Lobomycosis is endemic in certain regions of Central and South America, particularly in the Amazon basin. It is also seen in dolphins, which are believed to be a reservoir for the disease.
See Also[edit]
References[edit]
<references />
