Acral persistent papular mucinosis: Difference between revisions
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== | {{Infobox medical condition | ||
| name = Acral persistent papular mucinosis | |||
| synonyms = [[Papular mucinosis of infancy]], [[Lichen myxedematosus]] | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Papules]] on [[hands]] and [[feet]] | |||
| onset = [[Childhood]] or [[adulthood]] | |||
| duration = [[Chronic]] | |||
| causes = Unknown | |||
| | | risks = No known risk factors | ||
| | | diagnosis = [[Clinical diagnosis]] | ||
| | | differential = [[Scleromyxedema]], [[Lichen myxedematosus]] | ||
| | | treatment = [[Topical corticosteroids]], [[Phototherapy]] | ||
| | | prognosis = Generally [[benign]] | ||
| | | frequency = Rare | ||
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{{ | {{Short description|A rare skin condition characterized by mucin deposition}} | ||
'''Acral persistent papular mucinosis''' is a rare [[dermatological]] condition characterized by the presence of small, firm, skin-colored papules primarily located on the extremities. This condition is a form of [[mucinosis]], where there is an abnormal accumulation of [[mucin]] in the skin. | |||
[[ | ==Presentation== | ||
Acral persistent papular mucinosis typically presents as multiple, small, firm papules that are skin-colored or slightly translucent. These papules are usually found on the [[hands]], [[feet]], and other acral areas, which are the distal parts of the limbs. The papules are persistent and do not tend to resolve spontaneously. | |||
==Pathophysiology== | |||
The underlying cause of acral persistent papular mucinosis is the excessive deposition of mucin in the dermis. [[Mucin]] is a glycoprotein that is normally present in the skin, but in this condition, it accumulates in higher than normal amounts. The exact mechanism leading to this accumulation is not well understood, but it is thought to be related to an abnormality in the [[fibroblasts]] that produce mucin. | |||
==Diagnosis== | |||
The diagnosis of acral persistent papular mucinosis is primarily clinical, based on the characteristic appearance and distribution of the papules. A [[skin biopsy]] can be performed to confirm the diagnosis, which will show mucin deposition in the dermis upon histological examination. Special stains, such as Alcian blue, can be used to highlight the presence of mucin. | |||
==Treatment== | |||
There is no specific treatment for acral persistent papular mucinosis, and management is usually focused on symptomatic relief. In some cases, topical or intralesional [[corticosteroids]] may be used to reduce inflammation and improve the appearance of the papules. However, the condition is generally benign and does not require aggressive treatment. | |||
==Prognosis== | |||
Acral persistent papular mucinosis is a benign condition with a chronic course. The papules tend to persist over time but do not usually lead to any significant complications. The condition does not have any known association with systemic diseases. | |||
==Related pages== | |||
* [[Mucinosis]] | |||
* [[Dermatology]] | |||
* [[Skin biopsy]] | |||
[[Category:Dermatology]] | |||
[[Category:Rare diseases]] | |||
Latest revision as of 02:20, 4 April 2025
| Acral persistent papular mucinosis | |
|---|---|
| Synonyms | Papular mucinosis of infancy, Lichen myxedematosus |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Papules on hands and feet |
| Complications | N/A |
| Onset | Childhood or adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown |
| Risks | No known risk factors |
| Diagnosis | Clinical diagnosis |
| Differential diagnosis | Scleromyxedema, Lichen myxedematosus |
| Prevention | N/A |
| Treatment | Topical corticosteroids, Phototherapy |
| Medication | N/A |
| Prognosis | Generally benign |
| Frequency | Rare |
| Deaths | N/A |
A rare skin condition characterized by mucin deposition
Acral persistent papular mucinosis is a rare dermatological condition characterized by the presence of small, firm, skin-colored papules primarily located on the extremities. This condition is a form of mucinosis, where there is an abnormal accumulation of mucin in the skin.
Presentation[edit]
Acral persistent papular mucinosis typically presents as multiple, small, firm papules that are skin-colored or slightly translucent. These papules are usually found on the hands, feet, and other acral areas, which are the distal parts of the limbs. The papules are persistent and do not tend to resolve spontaneously.
Pathophysiology[edit]
The underlying cause of acral persistent papular mucinosis is the excessive deposition of mucin in the dermis. Mucin is a glycoprotein that is normally present in the skin, but in this condition, it accumulates in higher than normal amounts. The exact mechanism leading to this accumulation is not well understood, but it is thought to be related to an abnormality in the fibroblasts that produce mucin.
Diagnosis[edit]
The diagnosis of acral persistent papular mucinosis is primarily clinical, based on the characteristic appearance and distribution of the papules. A skin biopsy can be performed to confirm the diagnosis, which will show mucin deposition in the dermis upon histological examination. Special stains, such as Alcian blue, can be used to highlight the presence of mucin.
Treatment[edit]
There is no specific treatment for acral persistent papular mucinosis, and management is usually focused on symptomatic relief. In some cases, topical or intralesional corticosteroids may be used to reduce inflammation and improve the appearance of the papules. However, the condition is generally benign and does not require aggressive treatment.
Prognosis[edit]
Acral persistent papular mucinosis is a benign condition with a chronic course. The papules tend to persist over time but do not usually lead to any significant complications. The condition does not have any known association with systemic diseases.
