Angiolathyrism: Difference between revisions
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{{Infobox medical condition | |||
| name = Angiolathyrism | |||
| synonyms = | |||
| field = [[Vascular medicine]] | |||
| symptoms = [[Aneurysm]] formation, [[hypertension]], [[vascular disease]] | |||
| complications = [[Aortic dissection]], [[rupture of aneurysm]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = Consumption of [[Lathyrus sativus]] (grass pea) | |||
| risks = Prolonged dietary reliance on [[Lathyrus sativus]] | |||
| diagnosis = Clinical evaluation, [[imaging studies]] | |||
| differential = Other causes of [[aneurysm]] | |||
| prevention = Dietary diversification, avoidance of [[Lathyrus sativus]] | |||
| treatment = Management of [[hypertension]], surgical intervention for aneurysms | |||
| medication = [[Antihypertensive drugs]] | |||
| prognosis = Variable, depending on extent of vascular damage | |||
| frequency = Rare, more common in areas with high consumption of [[Lathyrus sativus]] | |||
}} | |||
'''Angiolathyrism''' is a rare medical condition that results from the consumption of certain types of legumes, specifically those from the genus ''Lathyrus''. This condition is characterized by the weakening and paralysis of the lower limbs. | '''Angiolathyrism''' is a rare medical condition that results from the consumption of certain types of legumes, specifically those from the genus ''Lathyrus''. This condition is characterized by the weakening and paralysis of the lower limbs. | ||
== Causes == | == Causes == | ||
The primary cause of angiolathyrism is the consumption of the ''Lathyrus'' genus of legumes, particularly ''Lathyrus sativus'', also known as grass pea or chickling vetch. These legumes contain a neurotoxic amino acid known as [[ODAP]] (β-N-oxalyl-L-α,β-diaminopropionic acid), which is believed to be the primary agent causing the condition. | |||
The primary cause of angiolathyrism is the consumption of the ''Lathyrus'' genus of legumes, particularly ''Lathyrus sativus'', also known as grass pea or chickling vetch. These legumes contain a neurotoxic amino acid known as [[ODAP]] ( | |||
== Symptoms == | == Symptoms == | ||
The symptoms of angiolathyrism typically include weakness and stiffness in the lower limbs, which can progress to paralysis. Other symptoms may include muscle pain, numbness, and difficulty walking. In severe cases, the condition can lead to permanent disability. | The symptoms of angiolathyrism typically include weakness and stiffness in the lower limbs, which can progress to paralysis. Other symptoms may include muscle pain, numbness, and difficulty walking. In severe cases, the condition can lead to permanent disability. | ||
== Treatment == | == Treatment == | ||
There is currently no specific treatment for angiolathyrism. Management of the condition primarily involves avoiding consumption of the offending legumes and providing supportive care to manage symptoms. | There is currently no specific treatment for angiolathyrism. Management of the condition primarily involves avoiding consumption of the offending legumes and providing supportive care to manage symptoms. | ||
== Prevention == | == Prevention == | ||
Prevention of angiolathyrism involves avoiding consumption of ''Lathyrus'' legumes, particularly in areas where these legumes are a staple food and other food sources are scarce. | Prevention of angiolathyrism involves avoiding consumption of ''Lathyrus'' legumes, particularly in areas where these legumes are a staple food and other food sources are scarce. | ||
== See also == | == See also == | ||
* [[Lathyrism]] | * [[Lathyrism]] | ||
* [[Neurotoxicity]] | * [[Neurotoxicity]] | ||
* [[Legumes]] | * [[Legumes]] | ||
* [[ODAP]] | * [[ODAP]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
{{stub}} | {{stub}} | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Toxicology]] | [[Category:Toxicology]] | ||
{{No image}} | |||
Latest revision as of 22:40, 3 April 2025
| Angiolathyrism | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Aneurysm formation, hypertension, vascular disease |
| Complications | Aortic dissection, rupture of aneurysm |
| Onset | |
| Duration | |
| Types | |
| Causes | Consumption of Lathyrus sativus (grass pea) |
| Risks | Prolonged dietary reliance on Lathyrus sativus |
| Diagnosis | Clinical evaluation, imaging studies |
| Differential diagnosis | Other causes of aneurysm |
| Prevention | Dietary diversification, avoidance of Lathyrus sativus |
| Treatment | Management of hypertension, surgical intervention for aneurysms |
| Medication | Antihypertensive drugs |
| Prognosis | Variable, depending on extent of vascular damage |
| Frequency | Rare, more common in areas with high consumption of Lathyrus sativus |
| Deaths | N/A |
Angiolathyrism is a rare medical condition that results from the consumption of certain types of legumes, specifically those from the genus Lathyrus. This condition is characterized by the weakening and paralysis of the lower limbs.
Causes[edit]
The primary cause of angiolathyrism is the consumption of the Lathyrus genus of legumes, particularly Lathyrus sativus, also known as grass pea or chickling vetch. These legumes contain a neurotoxic amino acid known as ODAP (β-N-oxalyl-L-α,β-diaminopropionic acid), which is believed to be the primary agent causing the condition.
Symptoms[edit]
The symptoms of angiolathyrism typically include weakness and stiffness in the lower limbs, which can progress to paralysis. Other symptoms may include muscle pain, numbness, and difficulty walking. In severe cases, the condition can lead to permanent disability.
Treatment[edit]
There is currently no specific treatment for angiolathyrism. Management of the condition primarily involves avoiding consumption of the offending legumes and providing supportive care to manage symptoms.
Prevention[edit]
Prevention of angiolathyrism involves avoiding consumption of Lathyrus legumes, particularly in areas where these legumes are a staple food and other food sources are scarce.
See also[edit]
References[edit]
<references />
