Parapsoriasis: Difference between revisions

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{{Infobox medical condition (new)
{{Infobox medical condition
| name            = Parapsoriasis
| name            = Parapsoriasis
| synonyms        =  
| synonyms        =  
| image          =
| specialty       = [[Dermatology]]
| caption        =
| symptoms        = [[Skin rash]], [[scaling]], [[itching]]
| pronounce       =  
| field          =
| symptoms        =  
| complications  =
| onset          =  
| onset          =  
| duration        =  
| duration        =  
| types          =
| causes          = Unknown
| causes          =  
| risks          =  
| risks          =  
| diagnosis      =  
| diagnosis      = [[Skin biopsy]], [[clinical examination]]
| differential    =  
| differential    = [[Psoriasis]], [[eczema]], [[cutaneous T-cell lymphoma]]
| prevention      =
| treatment      = [[Topical corticosteroids]], [[phototherapy]], [[systemic therapy]]
| treatment      =  
| medication      =  
| medication      =  
| prognosis      =
| frequency      = Rare
| frequency      =  
| deaths          =  
| deaths          =  
}}
}}
'''Parapsoriasis''' refers to one of a group of skin disorders that are characterized primarily by their resemblance to [[psoriasis]] (red, scaly lesions), rather than by their underlying cause.
{{Short description|A group of skin disorders with similarities to psoriasis}}
 
'''Parapsoriasis''' is a term used to describe a group of rare skin disorders that resemble [[psoriasis]] but have distinct differences in their clinical presentation and histopathology. These conditions are characterized by scaly patches or plaques on the skin, which can be persistent and may have a potential to progress to more serious conditions, such as [[cutaneous T-cell lymphoma]].
[[Neoplasm]]s can develop from parapsoriasis.<ref name="pmid-17975354">{{cite journal |vauthors=Sehgal VN, Srivastava G, Aggarwal AK |title=Parapsoriasis: a complex issue |journal=Skinmed |volume=6 |issue=6 |pages=280–6 |year=2007 |pmid=17975354 |doi=10.1111/j.1540-9740.2007.06490.x}}</ref> For example, it can develop into [[cutaneous T-cell lymphoma]].
 
The word "parapsoriasis" was formed in 1902.<ref name=parap81>{{cite journal |vauthors=Lambert WC, Everett MA |title=The nosology of parapsoriasis |journal=J. Am. Acad. Dermatol. |volume=5 |issue=4 |pages=373–95 |date=Oct 1981 |pmid=7026622 |doi=10.1016/S0190-9622(81)70100-2}}</ref>
 
==Classification==
==Classification==
The parapsoriasis groups, described and debated for nearly a century, has spawned a confusing nomenclature. There are some authors who prefer to limit the term "parapsoriasis" to large- and small-plaque variants only.<ref name=parap81/> However, the following classification scheme is now generally accepted:<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. {{ISBN|0-07-138076-0}}.</ref>{{rp|450}}
Parapsoriasis is generally classified into two main types based on the size and characteristics of the lesions:
 
===Small-plaque parapsoriasis===
* [[Large-plaque parapsoriasis]]
Small-plaque parapsoriasis, also known as "chronic superficial scaly dermatitis," is characterized by small, scaly patches that are usually less than 5 cm in diameter. These patches are often asymptomatic and can persist for many years without significant change. The lesions are typically found on the trunk and proximal extremities.
* [[Small-plaque parapsoriasis]]
===Large-plaque parapsoriasis===
* [[Pityriasis lichenoides]]
Large-plaque parapsoriasis is characterized by larger patches or plaques that are greater than 5 cm in diameter. These lesions may have a higher risk of progression to [[mycosis fungoides]], a type of cutaneous T-cell lymphoma. The plaques are often found on the trunk and may be accompanied by itching.
** [[Pityriasis lichenoides chronica]]
==Clinical Features==
** [[Pityriasis lichenoides et varioliformis acuta]]
The clinical presentation of parapsoriasis can vary, but common features include:
* [[Lymphomatoid papulosis]]
* Scaly patches or plaques on the skin
* Lesions that are often asymptomatic but may be itchy
* Chronic and persistent nature
* Potential for progression to more serious conditions
==Diagnosis==
==Diagnosis==
{{Empty section|date=May 2018}}
The diagnosis of parapsoriasis is primarily clinical, supported by histopathological examination of skin biopsies. Key features on biopsy include:
 
* Epidermal hyperplasia
== Treatment ==
* Parakeratosis
* Treatment of small plaque parapsoriasis is unnecessary but can include [[Emollient|emollients]], topical tar preparations or [[corticosteroids]], and/or [[phototherapy]].
* Lymphocytic infiltrate in the dermis
* Treatment of large plaque parapsoriasis is [[phototherapy]] or [[topical corticosteroids]].
Differential diagnosis includes [[psoriasis]], [[eczema]], and other forms of dermatitis.
 
==Management==
== See also ==
Management of parapsoriasis involves:
* [[Poikiloderma vasculare atrophicans]]
* Topical corticosteroids to reduce inflammation
* [[List of cutaneous conditions]]
* Phototherapy, such as narrowband UVB or PUVA
 
* Regular monitoring for signs of progression to cutaneous T-cell lymphoma
==References==
==Prognosis==
{{reflist}}
The prognosis of parapsoriasis varies depending on the type and potential for progression. Small-plaque parapsoriasis generally has a benign course, while large-plaque parapsoriasis requires careful monitoring due to the risk of progression to mycosis fungoides.
 
==Related pages==
== External links ==
* [[Psoriasis]]
{{Medical resources
* [[Mycosis fungoides]]
|  DiseasesDB    = 
* [[Cutaneous T-cell lymphoma]]
|  ICD10          = {{ICD10|L|41||l|40}}
[[Category:Dermatology]]
|  ICD9          = {{ICD9|696.2}} 
[[Category:Skin conditions]]
|  ICDO          =
|  OMIM          =
|  MedlinePlus    =
|  eMedicineSubj  = derm
|  eMedicineTopic = 311
|  MeshID        = D010267
}}
 
 
{{Diseases of the skin and appendages by morphology}}
{{Papulosquamous disorders}}
 
[[Category:Papulosquamous hyperkeratotic cutaneous conditions]]
 
 
{{Cutaneous-condition-stub}}
{{No image}}

Latest revision as of 06:06, 27 April 2025

Parapsoriasis
Synonyms
Pronounce N/A
Specialty Dermatology
Symptoms Skin rash, scaling, itching
Complications N/A
Onset
Duration
Types N/A
Causes Unknown
Risks
Diagnosis Skin biopsy, clinical examination
Differential diagnosis Psoriasis, eczema, cutaneous T-cell lymphoma
Prevention N/A
Treatment Topical corticosteroids, phototherapy, systemic therapy
Medication
Prognosis N/A
Frequency Rare
Deaths


A group of skin disorders with similarities to psoriasis


Parapsoriasis is a term used to describe a group of rare skin disorders that resemble psoriasis but have distinct differences in their clinical presentation and histopathology. These conditions are characterized by scaly patches or plaques on the skin, which can be persistent and may have a potential to progress to more serious conditions, such as cutaneous T-cell lymphoma.

Classification[edit]

Parapsoriasis is generally classified into two main types based on the size and characteristics of the lesions:

Small-plaque parapsoriasis[edit]

Small-plaque parapsoriasis, also known as "chronic superficial scaly dermatitis," is characterized by small, scaly patches that are usually less than 5 cm in diameter. These patches are often asymptomatic and can persist for many years without significant change. The lesions are typically found on the trunk and proximal extremities.

Large-plaque parapsoriasis[edit]

Large-plaque parapsoriasis is characterized by larger patches or plaques that are greater than 5 cm in diameter. These lesions may have a higher risk of progression to mycosis fungoides, a type of cutaneous T-cell lymphoma. The plaques are often found on the trunk and may be accompanied by itching.

Clinical Features[edit]

The clinical presentation of parapsoriasis can vary, but common features include:

  • Scaly patches or plaques on the skin
  • Lesions that are often asymptomatic but may be itchy
  • Chronic and persistent nature
  • Potential for progression to more serious conditions

Diagnosis[edit]

The diagnosis of parapsoriasis is primarily clinical, supported by histopathological examination of skin biopsies. Key features on biopsy include:

  • Epidermal hyperplasia
  • Parakeratosis
  • Lymphocytic infiltrate in the dermis

Differential diagnosis includes psoriasis, eczema, and other forms of dermatitis.

Management[edit]

Management of parapsoriasis involves:

  • Topical corticosteroids to reduce inflammation
  • Phototherapy, such as narrowband UVB or PUVA
  • Regular monitoring for signs of progression to cutaneous T-cell lymphoma

Prognosis[edit]

The prognosis of parapsoriasis varies depending on the type and potential for progression. Small-plaque parapsoriasis generally has a benign course, while large-plaque parapsoriasis requires careful monitoring due to the risk of progression to mycosis fungoides.

Related pages[edit]