Interstitial lung disease: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Interstitial lung disease | |||
| image = [[File:End-stage_interstitial_lung_disease_(honeycomb_lung).jpg|250px]] | |||
| caption = End-stage interstitial lung disease (honeycomb lung) | |||
| field = [[Pulmonology]] | |||
| symptoms = [[Shortness of breath]], [[cough]], [[fatigue (medical)|fatigue]] | |||
| complications = [[Pulmonary hypertension]], [[respiratory failure]], [[cor pulmonale]] | |||
| onset = Gradual | |||
| duration = Long term | |||
| causes = [[Autoimmune disease]], [[occupational exposure]], [[medications]], [[idiopathic]] | |||
| risks = [[Smoking]], [[environmental exposure]], [[genetic predisposition]] | |||
| diagnosis = [[Chest X-ray]], [[high-resolution computed tomography|HRCT]], [[lung biopsy]] | |||
| differential = [[Chronic obstructive pulmonary disease|COPD]], [[asthma]], [[heart failure]] | |||
| treatment = [[Corticosteroids]], [[immunosuppressive drug|immunosuppressants]], [[oxygen therapy]], [[lung transplantation]] | |||
| prognosis = Variable, often progressive | |||
| frequency = 70-80 per 100,000 people | |||
}} | |||
[[File:2_SVH_Lung_Health_Interstitial_Lung_Disease_final_1080.jpg|left|thumb|Interstitial lung disease]] | |||
[[File:Alveolus_diagram.svg|thumb|Alveolus diagram]] | |||
[[File:PCP_CAP_CXR.jpg|left|thumb|Interstitial lung disease]] | |||
'''Interstitial lung disease''' (ILD) refers to a group of [[lung diseases]] affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns over 200 different conditions. | '''Interstitial lung disease''' (ILD) refers to a group of [[lung diseases]] affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns over 200 different conditions. | ||
== Causes == | == Causes == | ||
The exact cause of ILD is often unknown, but they can be categorized into four main areas: exposure to occupational and environmental toxins, [[autoimmune diseases]], medications, and [[idiopathic]] (unknown cause). | The exact cause of ILD is often unknown, but they can be categorized into four main areas: exposure to occupational and environmental toxins, [[autoimmune diseases]], medications, and [[idiopathic]] (unknown cause). | ||
=== Occupational and Environmental Toxins === | === Occupational and Environmental Toxins === | ||
Certain jobs and exposures are linked to ILD, such as mining, farming, and working with asbestos. | Certain jobs and exposures are linked to ILD, such as mining, farming, and working with asbestos. | ||
=== Autoimmune Diseases === | === Autoimmune Diseases === | ||
ILD can be a complication of various autoimmune diseases such as [[rheumatoid arthritis]], [[scleroderma]], and [[lupus]]. | ILD can be a complication of various autoimmune diseases such as [[rheumatoid arthritis]], [[scleroderma]], and [[lupus]]. | ||
=== Medications === | === Medications === | ||
Some drugs can cause ILD, including chemotherapy drugs, heart medications, some antibiotics, and anti-inflammatory drugs. | Some drugs can cause ILD, including chemotherapy drugs, heart medications, some antibiotics, and anti-inflammatory drugs. | ||
=== Idiopathic === | === Idiopathic === | ||
In many cases, the cause of ILD is unknown. These are termed idiopathic interstitial pneumonias, the most common of which is idiopathic pulmonary fibrosis. | In many cases, the cause of ILD is unknown. These are termed idiopathic interstitial pneumonias, the most common of which is idiopathic pulmonary fibrosis. | ||
== Symptoms == | == Symptoms == | ||
Common symptoms of ILD include [[shortness of breath]], cough, and fatigue. In some cases, clubbing (widening and rounding) of the fingers and toes may occur. | Common symptoms of ILD include [[shortness of breath]], cough, and fatigue. In some cases, clubbing (widening and rounding) of the fingers and toes may occur. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of ILD typically involves imaging tests, lung function tests, and sometimes a lung biopsy. High-resolution computed tomography (HRCT) is often used. | Diagnosis of ILD typically involves imaging tests, lung function tests, and sometimes a lung biopsy. High-resolution computed tomography (HRCT) is often used. | ||
== Treatment == | == Treatment == | ||
Treatment for ILD is aimed at preserving lung function and quality of life, and can include medication, pulmonary rehabilitation, oxygen therapy, and in severe cases, lung transplant. | Treatment for ILD is aimed at preserving lung function and quality of life, and can include medication, pulmonary rehabilitation, oxygen therapy, and in severe cases, lung transplant. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for ILD varies widely depending on the specific type of disease, its cause, and the individual patient's health. Some forms of ILD can lead to respiratory failure and death. | The prognosis for ILD varies widely depending on the specific type of disease, its cause, and the individual patient's health. Some forms of ILD can lead to respiratory failure and death. | ||
== See Also == | == See Also == | ||
* [[Pulmonary fibrosis]] | * [[Pulmonary fibrosis]] | ||
| Line 34: | Line 45: | ||
* [[Scleroderma]] | * [[Scleroderma]] | ||
* [[Lupus]] | * [[Lupus]] | ||
[[Category:Respiratory diseases]] | [[Category:Respiratory diseases]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Occupational diseases]] | [[Category:Occupational diseases]] | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
Latest revision as of 22:19, 26 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Interstitial lung disease | |
|---|---|
.jpg)
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Shortness of breath, cough, fatigue |
| Complications | Pulmonary hypertension, respiratory failure, cor pulmonale |
| Onset | Gradual |
| Duration | Long term |
| Types | N/A |
| Causes | Autoimmune disease, occupational exposure, medications, idiopathic |
| Risks | Smoking, environmental exposure, genetic predisposition |
| Diagnosis | Chest X-ray, HRCT, lung biopsy |
| Differential diagnosis | COPD, asthma, heart failure |
| Prevention | N/A |
| Treatment | Corticosteroids, immunosuppressants, oxygen therapy, lung transplantation |
| Medication | N/A |
| Prognosis | Variable, often progressive |
| Frequency | 70-80 per 100,000 people |
| Deaths | N/A |
Interstitial lung disease (ILD) refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns over 200 different conditions.
Causes[edit]
The exact cause of ILD is often unknown, but they can be categorized into four main areas: exposure to occupational and environmental toxins, autoimmune diseases, medications, and idiopathic (unknown cause).
Occupational and Environmental Toxins[edit]
Certain jobs and exposures are linked to ILD, such as mining, farming, and working with asbestos.
Autoimmune Diseases[edit]
ILD can be a complication of various autoimmune diseases such as rheumatoid arthritis, scleroderma, and lupus.
Medications[edit]
Some drugs can cause ILD, including chemotherapy drugs, heart medications, some antibiotics, and anti-inflammatory drugs.
Idiopathic[edit]
In many cases, the cause of ILD is unknown. These are termed idiopathic interstitial pneumonias, the most common of which is idiopathic pulmonary fibrosis.
Symptoms[edit]
Common symptoms of ILD include shortness of breath, cough, and fatigue. In some cases, clubbing (widening and rounding) of the fingers and toes may occur.
Diagnosis[edit]
Diagnosis of ILD typically involves imaging tests, lung function tests, and sometimes a lung biopsy. High-resolution computed tomography (HRCT) is often used.
Treatment[edit]
Treatment for ILD is aimed at preserving lung function and quality of life, and can include medication, pulmonary rehabilitation, oxygen therapy, and in severe cases, lung transplant.
Prognosis[edit]
The prognosis for ILD varies widely depending on the specific type of disease, its cause, and the individual patient's health. Some forms of ILD can lead to respiratory failure and death.
See Also[edit]
