Ketonuria: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Ketonuria
| image          = [[File:Ketonuria.jpg]]
| caption        = Urine test strip showing positive result for ketones
| field          = [[Endocrinology]]
| symptoms        = Presence of [[ketone bodies]] in [[urine]]
| complications  = [[Dehydration]], [[electrolyte imbalance]]
| onset          = Acute or chronic
| duration        = Variable, depending on underlying cause
| causes          = [[Diabetes mellitus]], [[starvation]], [[low-carbohydrate diet]], [[alcoholism]]
| risks          = [[Diabetic ketoacidosis]], [[pregnancy]]
| diagnosis      = [[Urinalysis]]
| differential    = [[Diabetes mellitus]], [[starvation]], [[alcoholism]]
| prevention      = Managing underlying conditions, adequate [[carbohydrate]] intake
| treatment      = Addressing underlying cause, [[hydration]]
| frequency      = Common in uncontrolled [[diabetes]]
}}
= Ketonuria =
= Ketonuria =
== Introduction ==
== Introduction ==
'''Ketonuria''' refers to the presence of [[Ketone bodies|ketone bodies]] in the urine. Ketone bodies, which include acetoacetate, beta-hydroxybutyrate, and acetone, are produced by the liver from fatty acids during periods of low food intake, carbohydrate restrictive diets, prolonged intense exercise, or in untreated type 1 diabetes mellitus.
'''Ketonuria''' refers to the presence of [[Ketone bodies|ketone bodies]] in the urine. Ketone bodies, which include acetoacetate, beta-hydroxybutyrate, and acetone, are produced by the liver from fatty acids during periods of low food intake, carbohydrate restrictive diets, prolonged intense exercise, or in untreated type 1 diabetes mellitus.
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== Causes of Ketonuria ==
== Causes of Ketonuria ==
Ketonuria can occur due to various reasons, including:
Ketonuria can occur due to various reasons, including:
* [[Diabetes mellitus|Diabetes]]: Particularly in cases where it is poorly controlled or untreated.
* [[Diabetes mellitus|Diabetes]]: Particularly in cases where it is poorly controlled or untreated.
* Starvation or fasting: Leading to the breakdown of fatty acids.
* Starvation or fasting: Leading to the breakdown of fatty acids.
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* Prolonged exercise: Which can deplete glycogen stores in the body.
* Prolonged exercise: Which can deplete glycogen stores in the body.
* Alcoholism: Due to reduced food intake and increased fat metabolism.
* Alcoholism: Due to reduced food intake and increased fat metabolism.
== Symptoms and Diagnosis ==
== Symptoms and Diagnosis ==
While ketonuria itself may not present obvious symptoms, it can be an indicator of other underlying conditions. Diagnosis is typically made through urine tests, which can detect the presence of ketones.
While ketonuria itself may not present obvious symptoms, it can be an indicator of other underlying conditions. Diagnosis is typically made through urine tests, which can detect the presence of ketones.
 
[[File:Comp.Urine.Test.Strip.jpg|left|thumb|Urine test strip for detecting ketonuria.]]
[[File:Comp.Urine.Test.Strip.jpg|thumb|Urine test strip for detecting ketonuria.]]
 
== Health Implications ==
== Health Implications ==
The presence of ketones in the urine can be a sign of [[Ketoacidosis|ketoacidosis]], a serious complication of diabetes that requires immediate medical attention. In non-diabetic contexts, such as dieting or fasting, ketonuria may be a temporary condition.
The presence of ketones in the urine can be a sign of [[Ketoacidosis|ketoacidosis]], a serious complication of diabetes that requires immediate medical attention. In non-diabetic contexts, such as dieting or fasting, ketonuria may be a temporary condition.
== Treatment and Management ==
== Treatment and Management ==
Treatment of ketonuria involves addressing the underlying cause:
Treatment of ketonuria involves addressing the underlying cause:
* Managing diabetes effectively.
* Managing diabetes effectively.
* Adjusting diet and nutrition.
* Adjusting diet and nutrition.
* Ensuring adequate carbohydrate intake in the case of fasting or dieting.
* Ensuring adequate carbohydrate intake in the case of fasting or dieting.
* Medical intervention in the case of ketoacidosis.
* Medical intervention in the case of ketoacidosis.
== Prevention ==
== Prevention ==
Preventing ketonuria involves:
Preventing ketonuria involves:
* Effective management of diabetes.
* Effective management of diabetes.
* Balanced nutrition and avoidance of prolonged fasting.
* Balanced nutrition and avoidance of prolonged fasting.
* Regular medical check-ups for individuals at risk.
* Regular medical check-ups for individuals at risk.
== See Also ==
== See Also ==
* [[Diabetic ketoacidosis]]
* [[Diabetic ketoacidosis]]
* [[Urology]]
* [[Urology]]
* [[Metabolic disorders]]
* [[Metabolic disorders]]
== References ==
== References ==
<references>
<references>
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* {{cite web |url=https://www.diabetes.co.uk/diabetes-complications/ketonuria.html |title=Ketonuria |publisher=Diabetes.co.uk}}
* {{cite web |url=https://www.diabetes.co.uk/diabetes-complications/ketonuria.html |title=Ketonuria |publisher=Diabetes.co.uk}}
</references>
</references>
== External Links ==
== External Links ==
* [https://www.ada.org/en American Diabetes Association]
* [https://www.ada.org/en American Diabetes Association]
* [https://www.kidney.org/ National Kidney Foundation]
* [https://www.kidney.org/ National Kidney Foundation]
[[Category:Urinary system]]
[[Category:Urinary system]]
[[Category:Metabolic disorders]]
[[Category:Metabolic disorders]]
[[Category:Diabetes]]
[[Category:Diabetes]]
{{stub}}
{{stub}}

Latest revision as of 00:37, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Ketonuria
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Presence of ketone bodies in urine
Complications Dehydration, electrolyte imbalance
Onset Acute or chronic
Duration Variable, depending on underlying cause
Types N/A
Causes Diabetes mellitus, starvation, low-carbohydrate diet, alcoholism
Risks Diabetic ketoacidosis, pregnancy
Diagnosis Urinalysis
Differential diagnosis Diabetes mellitus, starvation, alcoholism
Prevention Managing underlying conditions, adequate carbohydrate intake
Treatment Addressing underlying cause, hydration
Medication N/A
Prognosis N/A
Frequency Common in uncontrolled diabetes
Deaths N/A


Ketonuria[edit]

Introduction[edit]

Ketonuria refers to the presence of ketone bodies in the urine. Ketone bodies, which include acetoacetate, beta-hydroxybutyrate, and acetone, are produced by the liver from fatty acids during periods of low food intake, carbohydrate restrictive diets, prolonged intense exercise, or in untreated type 1 diabetes mellitus.

Causes of Ketonuria[edit]

Ketonuria can occur due to various reasons, including:

  • Diabetes: Particularly in cases where it is poorly controlled or untreated.
  • Starvation or fasting: Leading to the breakdown of fatty acids.
  • Low-carbohydrate diets: Such as ketogenic diets.
  • Prolonged exercise: Which can deplete glycogen stores in the body.
  • Alcoholism: Due to reduced food intake and increased fat metabolism.

Symptoms and Diagnosis[edit]

While ketonuria itself may not present obvious symptoms, it can be an indicator of other underlying conditions. Diagnosis is typically made through urine tests, which can detect the presence of ketones.

Urine test strip for detecting ketonuria.

Health Implications[edit]

The presence of ketones in the urine can be a sign of ketoacidosis, a serious complication of diabetes that requires immediate medical attention. In non-diabetic contexts, such as dieting or fasting, ketonuria may be a temporary condition.

Treatment and Management[edit]

Treatment of ketonuria involves addressing the underlying cause:

  • Managing diabetes effectively.
  • Adjusting diet and nutrition.
  • Ensuring adequate carbohydrate intake in the case of fasting or dieting.
  • Medical intervention in the case of ketoacidosis.

Prevention[edit]

Preventing ketonuria involves:

  • Effective management of diabetes.
  • Balanced nutrition and avoidance of prolonged fasting.
  • Regular medical check-ups for individuals at risk.

See Also[edit]

References[edit]

<references>

  • ,
 Ketonuria and the management of diabetic ketoacidosis, 
 Diabetic Medicine, 
 2020,

Ketonuria(link). {{{website}}}. Diabetes.co.uk.



</references>

External Links[edit]

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