Subacute thyroiditis: Difference between revisions
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{{Infobox medical condition | |||
| name = Subacute thyroiditis | |||
| image = [[File:Subacute_thyroiditis_-_intermed_mag.jpg|left|thumb|Subacute thyroiditis]] | |||
| caption = Micrograph of subacute thyroiditis showing characteristic giant cells | |||
| field = [[Endocrinology]] | |||
| synonyms = De Quervain's thyroiditis, granulomatous thyroiditis | |||
| symptoms = [[Neck pain]], [[fever]], [[fatigue]], [[dysphagia]] | |||
| complications = [[Hypothyroidism]], [[thyrotoxicosis]] | |||
| onset = Sudden | |||
| duration = Weeks to months | |||
| causes = Often follows a [[viral infection]] | |||
| risks = Recent [[upper respiratory tract infection]] | |||
| diagnosis = [[Thyroid function tests]], [[ESR]], [[CRP]], [[ultrasound]] | |||
| differential = [[Hashimoto's thyroiditis]], [[Graves' disease]], [[thyroid cancer]] | |||
| treatment = [[NSAIDs]], [[corticosteroids]] | |||
| prognosis = Generally good, self-limiting | |||
| frequency = Rare | |||
}} | |||
'''Subacute thyroiditis''' (also known as '''de Quervain's thyroiditis''' and '''giant cell thyroiditis''') is a form of [[thyroiditis]] that is usually self-limiting, of viral origin, and accompanied by systemic symptoms. It is characterized by neck pain, systemic symptoms, and an elevated erythrocyte sedimentation rate (ESR). | '''Subacute thyroiditis''' (also known as '''de Quervain's thyroiditis''' and '''giant cell thyroiditis''') is a form of [[thyroiditis]] that is usually self-limiting, of viral origin, and accompanied by systemic symptoms. It is characterized by neck pain, systemic symptoms, and an elevated erythrocyte sedimentation rate (ESR). | ||
== Signs and Symptoms == | == Signs and Symptoms == | ||
Patients with subacute thyroiditis typically present with a triphasic pattern of thyroid dysfunction. The initial phase is characterized by neck pain and systemic symptoms, including fever, malaise, and myalgia. This is followed by a thyrotoxic phase, during which patients may experience symptoms such as weight loss, heat intolerance, and palpitations. The final phase is a hypothyroid phase, which may last for several months. | Patients with subacute thyroiditis typically present with a triphasic pattern of thyroid dysfunction. The initial phase is characterized by neck pain and systemic symptoms, including fever, malaise, and myalgia. This is followed by a thyrotoxic phase, during which patients may experience symptoms such as weight loss, heat intolerance, and palpitations. The final phase is a hypothyroid phase, which may last for several months. | ||
== Causes == | == Causes == | ||
The exact cause of subacute thyroiditis is unknown, but it is believed to be related to a viral infection. The condition is often preceded by an upper respiratory tract infection, and it has been associated with several viruses, including mumps, influenza, and coxsackie viruses. | The exact cause of subacute thyroiditis is unknown, but it is believed to be related to a viral infection. The condition is often preceded by an upper respiratory tract infection, and it has been associated with several viruses, including mumps, influenza, and coxsackie viruses. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of subacute thyroiditis is typically based on the patient's clinical presentation and laboratory findings. The most characteristic laboratory finding is an elevated erythrocyte sedimentation rate (ESR). Other common findings include a low uptake of radioactive iodine by the thyroid gland and elevated levels of thyroid hormones in the blood. | The diagnosis of subacute thyroiditis is typically based on the patient's clinical presentation and laboratory findings. The most characteristic laboratory finding is an elevated erythrocyte sedimentation rate (ESR). Other common findings include a low uptake of radioactive iodine by the thyroid gland and elevated levels of thyroid hormones in the blood. | ||
== Treatment == | == Treatment == | ||
The treatment of subacute thyroiditis is primarily symptomatic. Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to relieve pain and reduce inflammation. In severe cases, corticosteroids may be used. Once the thyrotoxic phase has resolved, patients may require treatment with thyroid hormone replacement therapy. | The treatment of subacute thyroiditis is primarily symptomatic. Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to relieve pain and reduce inflammation. In severe cases, corticosteroids may be used. Once the thyrotoxic phase has resolved, patients may require treatment with thyroid hormone replacement therapy. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for subacute thyroiditis is generally good. Most patients recover completely within a few months, although some may experience a recurrence of symptoms. | The prognosis for subacute thyroiditis is generally good. Most patients recover completely within a few months, although some may experience a recurrence of symptoms. | ||
== See Also == | == See Also == | ||
* [[Thyroiditis]] | * [[Thyroiditis]] | ||
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* [[Thyroid hormones]] | * [[Thyroid hormones]] | ||
* [[Inflammation]] | * [[Inflammation]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Endocrine diseases]] | [[Category:Endocrine diseases]] | ||
[[Category:Thyroid disease]] | [[Category:Thyroid disease]] | ||
[[Category:Inflammation]] | [[Category:Inflammation]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 22:54, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Subacute thyroiditis | |
|---|---|
 | |
| Synonyms | De Quervain's thyroiditis, granulomatous thyroiditis |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Neck pain, fever, fatigue, dysphagia |
| Complications | Hypothyroidism, thyrotoxicosis |
| Onset | Sudden |
| Duration | Weeks to months |
| Types | N/A |
| Causes | Often follows a viral infection |
| Risks | Recent upper respiratory tract infection |
| Diagnosis | Thyroid function tests, ESR, CRP, ultrasound |
| Differential diagnosis | Hashimoto's thyroiditis, Graves' disease, thyroid cancer |
| Prevention | N/A |
| Treatment | NSAIDs, corticosteroids |
| Medication | N/A |
| Prognosis | Generally good, self-limiting |
| Frequency | Rare |
| Deaths | N/A |
Subacute thyroiditis (also known as de Quervain's thyroiditis and giant cell thyroiditis) is a form of thyroiditis that is usually self-limiting, of viral origin, and accompanied by systemic symptoms. It is characterized by neck pain, systemic symptoms, and an elevated erythrocyte sedimentation rate (ESR).
Signs and Symptoms[edit]
Patients with subacute thyroiditis typically present with a triphasic pattern of thyroid dysfunction. The initial phase is characterized by neck pain and systemic symptoms, including fever, malaise, and myalgia. This is followed by a thyrotoxic phase, during which patients may experience symptoms such as weight loss, heat intolerance, and palpitations. The final phase is a hypothyroid phase, which may last for several months.
Causes[edit]
The exact cause of subacute thyroiditis is unknown, but it is believed to be related to a viral infection. The condition is often preceded by an upper respiratory tract infection, and it has been associated with several viruses, including mumps, influenza, and coxsackie viruses.
Diagnosis[edit]
The diagnosis of subacute thyroiditis is typically based on the patient's clinical presentation and laboratory findings. The most characteristic laboratory finding is an elevated erythrocyte sedimentation rate (ESR). Other common findings include a low uptake of radioactive iodine by the thyroid gland and elevated levels of thyroid hormones in the blood.
Treatment[edit]
The treatment of subacute thyroiditis is primarily symptomatic. Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to relieve pain and reduce inflammation. In severe cases, corticosteroids may be used. Once the thyrotoxic phase has resolved, patients may require treatment with thyroid hormone replacement therapy.
Prognosis[edit]
The prognosis for subacute thyroiditis is generally good. Most patients recover completely within a few months, although some may experience a recurrence of symptoms.
See Also[edit]
References[edit]
<references />
