Hypoalphalipoproteinemia: Difference between revisions
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{{Infobox medical condition | |||
| name = Hypoalphalipoproteinemia | |||
| image = [[File:Autosomal_dominant_-_en.svg|200px]] | |||
| caption = Hypoalphalipoproteinemia is often inherited in an [[autosomal dominant]] pattern. | |||
| synonyms = Low HDL cholesterol | |||
| pronounce = | |||
| specialty = [[Endocrinology]] | |||
| symptoms = Low levels of [[high-density lipoprotein]] (HDL) cholesterol | |||
| complications = Increased risk of [[cardiovascular disease]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = Genetic mutations, lifestyle factors | |||
| risks = Family history, poor diet, lack of exercise | |||
| diagnosis = [[Blood test]] measuring HDL levels | |||
| differential = [[Tangier disease]], [[Familial hypercholesterolemia]] | |||
| prevention = Healthy lifestyle, regular exercise | |||
| treatment = Lifestyle changes, medications | |||
| medication = [[Statins]], [[Niacin]] | |||
| prognosis = Variable, depending on management | |||
| frequency = Rare | |||
}} | |||
'''Hypoalphalipoproteinemia''' is a medical condition characterized by decreased levels of [[High-density lipoprotein|high-density lipoprotein (HDL)]] in the blood. HDL is often referred to as "good cholesterol" because it carries cholesterol from other parts of your body back to your liver, which removes the cholesterol from your body. | '''Hypoalphalipoproteinemia''' is a medical condition characterized by decreased levels of [[High-density lipoprotein|high-density lipoprotein (HDL)]] in the blood. HDL is often referred to as "good cholesterol" because it carries cholesterol from other parts of your body back to your liver, which removes the cholesterol from your body. | ||
== Causes == | == Causes == | ||
Hypoalphalipoproteinemia can be caused by a variety of factors, including [[genetics]], lifestyle choices, and certain medical conditions. Genetic causes include mutations in genes such as [[Apolipoprotein A-I|APOA1]], [[Apolipoprotein C-III|APOC3]], and [[Lecithin–cholesterol acyltransferase|LCAT]]. Lifestyle factors that can contribute to hypoalphalipoproteinemia include [[smoking]], lack of [[Physical exercise|exercise]], and a diet high in [[saturated fat]] and [[cholesterol]]. Medical conditions that can cause hypoalphalipoproteinemia include [[Type 2 diabetes|type 2 diabetes]], [[Obesity|obesity]], and [[Metabolic syndrome|metabolic syndrome]]. | Hypoalphalipoproteinemia can be caused by a variety of factors, including [[genetics]], lifestyle choices, and certain medical conditions. Genetic causes include mutations in genes such as [[Apolipoprotein A-I|APOA1]], [[Apolipoprotein C-III|APOC3]], and [[Lecithin–cholesterol acyltransferase|LCAT]]. Lifestyle factors that can contribute to hypoalphalipoproteinemia include [[smoking]], lack of [[Physical exercise|exercise]], and a diet high in [[saturated fat]] and [[cholesterol]]. Medical conditions that can cause hypoalphalipoproteinemia include [[Type 2 diabetes|type 2 diabetes]], [[Obesity|obesity]], and [[Metabolic syndrome|metabolic syndrome]]. | ||
== Symptoms == | == Symptoms == | ||
Hypoalphalipoproteinemia itself does not cause symptoms. However, because HDL plays a crucial role in removing cholesterol from the body, individuals with hypoalphalipoproteinemia are at an increased risk of developing [[Atherosclerosis|atherosclerosis]] and [[Coronary artery disease|coronary artery disease]]. These conditions can lead to symptoms such as chest pain, shortness of breath, and fatigue. | Hypoalphalipoproteinemia itself does not cause symptoms. However, because HDL plays a crucial role in removing cholesterol from the body, individuals with hypoalphalipoproteinemia are at an increased risk of developing [[Atherosclerosis|atherosclerosis]] and [[Coronary artery disease|coronary artery disease]]. These conditions can lead to symptoms such as chest pain, shortness of breath, and fatigue. | ||
== Diagnosis == | == Diagnosis == | ||
Hypoalphalipoproteinemia is typically diagnosed through a [[Blood test|blood test]] that measures the levels of different types of cholesterol in the blood. If the levels of HDL are found to be below the normal range, a diagnosis of hypoalphalipoproteinemia may be made. | Hypoalphalipoproteinemia is typically diagnosed through a [[Blood test|blood test]] that measures the levels of different types of cholesterol in the blood. If the levels of HDL are found to be below the normal range, a diagnosis of hypoalphalipoproteinemia may be made. | ||
== Treatment == | == Treatment == | ||
Treatment for hypoalphalipoproteinemia typically involves lifestyle changes such as quitting smoking, increasing physical activity, and adopting a diet low in saturated fat and cholesterol. In some cases, medication may be prescribed to increase HDL levels. | Treatment for hypoalphalipoproteinemia typically involves lifestyle changes such as quitting smoking, increasing physical activity, and adopting a diet low in saturated fat and cholesterol. In some cases, medication may be prescribed to increase HDL levels. | ||
== See also == | == See also == | ||
* [[Hyperlipidemia]] | * [[Hyperlipidemia]] | ||
* [[Dyslipidemia]] | * [[Dyslipidemia]] | ||
* [[Lipoprotein metabolism]] | * [[Lipoprotein metabolism]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Metabolic disorders]] | [[Category:Metabolic disorders]] | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
Latest revision as of 21:44, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Hypoalphalipoproteinemia | |
|---|---|
| |
| Synonyms | Low HDL cholesterol |
| Pronounce | |
| Specialty | Endocrinology |
| Symptoms | Low levels of high-density lipoprotein (HDL) cholesterol |
| Complications | Increased risk of cardiovascular disease |
| Onset | |
| Duration | |
| Types | |
| Causes | Genetic mutations, lifestyle factors |
| Risks | Family history, poor diet, lack of exercise |
| Diagnosis | Blood test measuring HDL levels |
| Differential diagnosis | Tangier disease, Familial hypercholesterolemia |
| Prevention | Healthy lifestyle, regular exercise |
| Treatment | Lifestyle changes, medications |
| Medication | Statins, Niacin |
| Prognosis | Variable, depending on management |
| Frequency | Rare |
| Deaths | N/A |
Hypoalphalipoproteinemia is a medical condition characterized by decreased levels of high-density lipoprotein (HDL) in the blood. HDL is often referred to as "good cholesterol" because it carries cholesterol from other parts of your body back to your liver, which removes the cholesterol from your body.
Causes[edit]
Hypoalphalipoproteinemia can be caused by a variety of factors, including genetics, lifestyle choices, and certain medical conditions. Genetic causes include mutations in genes such as APOA1, APOC3, and LCAT. Lifestyle factors that can contribute to hypoalphalipoproteinemia include smoking, lack of exercise, and a diet high in saturated fat and cholesterol. Medical conditions that can cause hypoalphalipoproteinemia include type 2 diabetes, obesity, and metabolic syndrome.
Symptoms[edit]
Hypoalphalipoproteinemia itself does not cause symptoms. However, because HDL plays a crucial role in removing cholesterol from the body, individuals with hypoalphalipoproteinemia are at an increased risk of developing atherosclerosis and coronary artery disease. These conditions can lead to symptoms such as chest pain, shortness of breath, and fatigue.
Diagnosis[edit]
Hypoalphalipoproteinemia is typically diagnosed through a blood test that measures the levels of different types of cholesterol in the blood. If the levels of HDL are found to be below the normal range, a diagnosis of hypoalphalipoproteinemia may be made.
Treatment[edit]
Treatment for hypoalphalipoproteinemia typically involves lifestyle changes such as quitting smoking, increasing physical activity, and adopting a diet low in saturated fat and cholesterol. In some cases, medication may be prescribed to increase HDL levels.
See also[edit]
