Fibrosarcoma: Difference between revisions

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'''Fibrosarcoma''' is a type of [[tumor]] that originates in fibrous connective tissue. It is a rare form of [[cancer]], accounting for less than 1% of all adult cancers, but it is more common in children, where it accounts for approximately 5% of all soft tissue sarcomas.
{{SI}}
 
{{Infobox medical condition
== Symptoms ==
| name            = Fibrosarcoma
The symptoms of fibrosarcoma can vary depending on the location of the tumor. Common symptoms include a noticeable lump or swelling, pain if the tumor is pressing on nerves or muscles, and fatigue.
| image          = [[File:Malignant_peripheral_nerve_sheath_tumour_-_high_mag.jpg|left|thumb|Fibrosarcoma under a microscope]]
 
| caption        = Histopathological image of fibrosarcoma
== Causes ==
| field          = [[Oncology]]
The exact cause of fibrosarcoma is unknown. However, it is believed to be related to genetic mutations. Some cases have been associated with exposure to certain chemicals or radiation.
| synonyms        =
 
| symptoms        = [[Swelling]], [[pain]], [[lump]]
== Diagnosis ==
| complications  = [[Metastasis]], [[recurrence]]
Diagnosis of fibrosarcoma typically involves a physical examination, imaging tests such as [[MRI]] or [[CT scan]], and a biopsy to examine the cells under a microscope.
| onset          = Typically in [[adults]]
 
| duration        =
== Treatment ==
| types          =
Treatment for fibrosarcoma usually involves surgery to remove the tumor. This may be followed by radiation therapy or chemotherapy to kill any remaining cancer cells. In some cases, targeted therapy or immunotherapy may be used.
| causes          =
 
| risks          = [[Genetic predisposition]], [[radiation exposure]]
== Prognosis ==
| diagnosis      = [[Biopsy]], [[imaging studies]]
The prognosis for fibrosarcoma depends on a number of factors, including the size and location of the tumor, whether it has spread to other parts of the body, and the patient's overall health.
| differential    = [[Liposarcoma]], [[leiomyosarcoma]], [[malignant peripheral nerve sheath tumor]]
 
| prevention      =
== See also ==
| treatment      = [[Surgery]], [[radiation therapy]], [[chemotherapy]]
* [[Sarcoma]]
| medication      =
* [[Cancer]]
| prognosis      = Variable, depends on stage and location
* [[Chemotherapy]]
| frequency      = Rare
* [[Radiation therapy]]
}}
 
{{short description|A type of cancer that develops from fibrous connective tissue}}
[[Category:Cancer]]
{{For|the condition in cats|Vaccine-associated sarcoma}}
[[Category:Rare diseases]]
== Introduction ==
[[Category:Pediatric cancers]]
[[File:Cat_after_Fibrosarcom_op.jpg|left|thumb|A cat post-surgery for fibrosarcoma]]
 
'''Fibrosarcoma''' is a malignant [[tumor]] that arises from [[fibroblasts]], the cells responsible for producing [[collagen]] and other fibers. It is a type of [[soft tissue sarcoma]] and can occur in any part of the body, although it is most commonly found in the [[extremities]], [[trunk]], and [[head and neck]] region.
{{stub}}
==Pathophysiology==
Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The [[histological]] appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.
==Clinical Presentation==
Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the [[lungs]] and other organs.
==Diagnosis==
The diagnosis of fibrosarcoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. Imaging techniques such as [[MRI]] and [[CT scan]] are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.
==Treatment==
The primary treatment for fibrosarcoma is [[surgical resection]] with wide margins to ensure complete removal of the tumor. In some cases, [[radiation therapy]] and/or [[chemotherapy]] may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.
==Prognosis==
The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.
==See also==
* [[Soft tissue sarcoma]]
* [[Vaccine-associated sarcoma]]
* [[Oncology]]
[[Category:Oncology]]
[[Category:Sarcoma]]

Latest revision as of 16:31, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Fibrosarcoma
Fibrosarcoma under a microscope
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Swelling, pain, lump
Complications Metastasis, recurrence
Onset Typically in adults
Duration
Types
Causes
Risks Genetic predisposition, radiation exposure
Diagnosis Biopsy, imaging studies
Differential diagnosis Liposarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor
Prevention
Treatment Surgery, radiation therapy, chemotherapy
Medication
Prognosis Variable, depends on stage and location
Frequency Rare
Deaths N/A


A type of cancer that develops from fibrous connective tissue


Introduction[edit]

A cat post-surgery for fibrosarcoma

Fibrosarcoma is a malignant tumor that arises from fibroblasts, the cells responsible for producing collagen and other fibers. It is a type of soft tissue sarcoma and can occur in any part of the body, although it is most commonly found in the extremities, trunk, and head and neck region.

Pathophysiology[edit]

Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The histological appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.

Clinical Presentation[edit]

Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the lungs and other organs.

Diagnosis[edit]

The diagnosis of fibrosarcoma is typically made through a combination of imaging studies and biopsy. Imaging techniques such as MRI and CT scan are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.

Treatment[edit]

The primary treatment for fibrosarcoma is surgical resection with wide margins to ensure complete removal of the tumor. In some cases, radiation therapy and/or chemotherapy may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.

Prognosis[edit]

The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.

See also[edit]