Vaccine adverse event: Difference between revisions
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{{Infobox medical condition | |||
| name = Vaccine adverse event | |||
| synonyms = [[Vaccine side effect]], [[Vaccine reaction]] | |||
| field = [[Immunology]], [[Infectious disease]] | |||
| symptoms = [[Fever]], [[Fatigue (medical)]], [[Headache]], [[Myalgia]], [[Arthralgia]], [[Anaphylaxis]] | |||
| complications = [[Guillain–Barré syndrome]], [[Thrombosis with thrombocytopenia syndrome]], [[Myocarditis]], [[Pericarditis]] | |||
| onset = Minutes to weeks after vaccination | |||
| duration = Varies, typically short-term | |||
| causes = [[Immune response]] to [[vaccine]] | |||
| risks = [[Allergy]], [[Autoimmune disease]], [[Immunocompromised state]] | |||
| diagnosis = Clinical evaluation, [[Medical history]], [[Allergy testing]] | |||
| differential = [[Infectious disease]], [[Autoimmune disorder]], [[Allergic reaction]] | |||
| prevention = [[Pre-vaccination screening]], [[Observation period]] post-vaccination | |||
| treatment = [[Antihistamines]], [[Corticosteroids]], [[Epinephrine]] for severe reactions | |||
| prognosis = Generally good, most reactions are mild and self-limiting | |||
| frequency = Varies by vaccine, generally rare | |||
| deaths = Rare, associated with severe reactions | |||
}} | |||
'''Vaccine Adverse Event''' | '''Vaccine Adverse Event''' | ||
A '''[[Vaccine adverse event]]''' (VAE) refers to any untoward medical occurrence that may present during treatment with a [[vaccine]], but which does not necessarily have a causal relationship with the treatment. The term is used in the context of [[pharmacovigilance]], which is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. | A '''[[Vaccine adverse event]]''' (VAE) refers to any untoward medical occurrence that may present during treatment with a [[vaccine]], but which does not necessarily have a causal relationship with the treatment. The term is used in the context of [[pharmacovigilance]], which is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. | ||
==Definition== | ==Definition== | ||
A vaccine adverse event is defined as an untoward medical occurrence that follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavorable or unintended sign, abnormal laboratory finding, symptom or disease. | A vaccine adverse event is defined as an untoward medical occurrence that follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavorable or unintended sign, abnormal laboratory finding, symptom or disease. | ||
==Types of Vaccine Adverse Events== | ==Types of Vaccine Adverse Events== | ||
Vaccine adverse events can be classified into two main categories: [[Vaccine Adverse Event Reporting System|VAERS]] and [[Vaccine Safety Datalink|VSD]]. VAERS is a national system for monitoring the safety of vaccines, while VSD is a group of healthcare organizations across the nation that conducts research on vaccine safety. | Vaccine adverse events can be classified into two main categories: [[Vaccine Adverse Event Reporting System|VAERS]] and [[Vaccine Safety Datalink|VSD]]. VAERS is a national system for monitoring the safety of vaccines, while VSD is a group of healthcare organizations across the nation that conducts research on vaccine safety. | ||
==Reporting of Vaccine Adverse Events== | ==Reporting of Vaccine Adverse Events== | ||
In many countries, healthcare providers are required to report certain vaccine adverse events to a national [[vaccine adverse event reporting system]]. In the United States, for example, this system is known as the [[Vaccine Adverse Event Reporting System]] (VAERS). | In many countries, healthcare providers are required to report certain vaccine adverse events to a national [[vaccine adverse event reporting system]]. In the United States, for example, this system is known as the [[Vaccine Adverse Event Reporting System]] (VAERS). | ||
==Prevention and Management== | ==Prevention and Management== | ||
Prevention and management of vaccine adverse events involve careful screening for contraindications and precautions, appropriate handling and administration of vaccines, and observation of vaccine recipients. | Prevention and management of vaccine adverse events involve careful screening for contraindications and precautions, appropriate handling and administration of vaccines, and observation of vaccine recipients. | ||
==See Also== | ==See Also== | ||
* [[Vaccine]] | * [[Vaccine]] | ||
* [[Adverse event]] | * [[Adverse event]] | ||
| Line 26: | Line 34: | ||
* [[Vaccine Adverse Event Reporting System]] | * [[Vaccine Adverse Event Reporting System]] | ||
* [[Vaccine Safety Datalink]] | * [[Vaccine Safety Datalink]] | ||
[[Category:Vaccination]] | [[Category:Vaccination]] | ||
[[Category:Pharmacovigilance]] | [[Category:Pharmacovigilance]] | ||
[[Category:Adverse event]] | [[Category:Adverse event]] | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
{{No image}} | |||
Latest revision as of 05:56, 4 April 2025
| Vaccine adverse event | |
|---|---|
| Synonyms | Vaccine side effect, Vaccine reaction |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fever, Fatigue (medical), Headache, Myalgia, Arthralgia, Anaphylaxis |
| Complications | Guillain–Barré syndrome, Thrombosis with thrombocytopenia syndrome, Myocarditis, Pericarditis |
| Onset | Minutes to weeks after vaccination |
| Duration | Varies, typically short-term |
| Types | N/A |
| Causes | Immune response to vaccine |
| Risks | Allergy, Autoimmune disease, Immunocompromised state |
| Diagnosis | Clinical evaluation, Medical history, Allergy testing |
| Differential diagnosis | Infectious disease, Autoimmune disorder, Allergic reaction |
| Prevention | Pre-vaccination screening, Observation period post-vaccination |
| Treatment | Antihistamines, Corticosteroids, Epinephrine for severe reactions |
| Medication | N/A |
| Prognosis | Generally good, most reactions are mild and self-limiting |
| Frequency | Varies by vaccine, generally rare |
| Deaths | Rare, associated with severe reactions |
Vaccine Adverse Event
A Vaccine adverse event (VAE) refers to any untoward medical occurrence that may present during treatment with a vaccine, but which does not necessarily have a causal relationship with the treatment. The term is used in the context of pharmacovigilance, which is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem.
Definition[edit]
A vaccine adverse event is defined as an untoward medical occurrence that follows immunization and which does not necessarily have a causal relationship with the usage of the vaccine. The adverse event may be any unfavorable or unintended sign, abnormal laboratory finding, symptom or disease.
Types of Vaccine Adverse Events[edit]
Vaccine adverse events can be classified into two main categories: VAERS and VSD. VAERS is a national system for monitoring the safety of vaccines, while VSD is a group of healthcare organizations across the nation that conducts research on vaccine safety.
Reporting of Vaccine Adverse Events[edit]
In many countries, healthcare providers are required to report certain vaccine adverse events to a national vaccine adverse event reporting system. In the United States, for example, this system is known as the Vaccine Adverse Event Reporting System (VAERS).
Prevention and Management[edit]
Prevention and management of vaccine adverse events involve careful screening for contraindications and precautions, appropriate handling and administration of vaccines, and observation of vaccine recipients.
