Ross' syndrome: Difference between revisions

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{{Infobox medical condition
| name            = Ross' syndrome
| synonyms        =
| specialty      = [[Neurology]], [[Dermatology]]
| symptoms        = [[Anhidrosis]], [[Areflexia]], [[Miosis]], [[Horner's syndrome]]
| onset          =
| duration        =
| causes          = Unknown
| risks          =
| diagnosis      = Clinical evaluation, [[Autonomic testing]]
| differential    = [[Holmes-Adie syndrome]], [[Horner's syndrome]], [[Diabetic neuropathy]]
| treatment      = Symptomatic management
| medication      =
| prognosis      = Variable
| frequency      = Rare
}}
'''Ross' syndrome''' is a rare disorder characterized by a triad of symptoms: [[hypohidrosis]] (reduced ability to sweat), [[Adie's pupil]] (a pupil that does not react to light), and [[areflexia]] (absence of neurologic reflexes). It was first described by Douglas Ross in 1958.
'''Ross' syndrome''' is a rare disorder characterized by a triad of symptoms: [[hypohidrosis]] (reduced ability to sweat), [[Adie's pupil]] (a pupil that does not react to light), and [[areflexia]] (absence of neurologic reflexes). It was first described by Douglas Ross in 1958.
==Etiology==
==Etiology==
The exact cause of Ross' syndrome is unknown. It is thought to be due to damage to the [[autonomic nervous system]], specifically the [[parasympathetic nervous system]]. This damage may be caused by an [[autoimmune]] process, but this is not confirmed.
The exact cause of Ross' syndrome is unknown. It is thought to be due to damage to the [[autonomic nervous system]], specifically the [[parasympathetic nervous system]]. This damage may be caused by an [[autoimmune]] process, but this is not confirmed.
==Clinical Features==
==Clinical Features==
The main features of Ross' syndrome are:
The main features of Ross' syndrome are:
* '''Hypohidrosis''': This is usually the first symptom to appear. It is often patchy and asymmetric, affecting one side of the body more than the other. It can lead to heat intolerance and fever.
* '''Hypohidrosis''': This is usually the first symptom to appear. It is often patchy and asymmetric, affecting one side of the body more than the other. It can lead to heat intolerance and fever.
* '''Adie's pupil''': This is a condition where the pupil is dilated and reacts slowly, or not at all, to light. It usually affects one eye but can affect both.
* '''Adie's pupil''': This is a condition where the pupil is dilated and reacts slowly, or not at all, to light. It usually affects one eye but can affect both.
* '''Areflexia''': This is a lack of reflexes, particularly in the lower limbs. It can lead to difficulty with balance and coordination.
* '''Areflexia''': This is a lack of reflexes, particularly in the lower limbs. It can lead to difficulty with balance and coordination.
==Diagnosis==
==Diagnosis==
Diagnosis of Ross' syndrome is based on the clinical features. There is no specific test for the condition. Other conditions that can cause similar symptoms, such as [[Horner's syndrome]] and [[Harlequin syndrome]], should be ruled out.
Diagnosis of Ross' syndrome is based on the clinical features. There is no specific test for the condition. Other conditions that can cause similar symptoms, such as [[Horner's syndrome]] and [[Harlequin syndrome]], should be ruled out.
==Treatment==
==Treatment==
There is no cure for Ross' syndrome. Treatment is aimed at managing the symptoms. This may include using artificial tears for dry eyes, wearing cool clothing and staying in cool environments to manage heat intolerance, and physical therapy for balance and coordination problems.
There is no cure for Ross' syndrome. Treatment is aimed at managing the symptoms. This may include using artificial tears for dry eyes, wearing cool clothing and staying in cool environments to manage heat intolerance, and physical therapy for balance and coordination problems.
==Prognosis==
==Prognosis==
The prognosis for Ross' syndrome is generally good. The condition is not life-threatening, but it can cause significant discomfort and inconvenience. The symptoms tend to progress slowly over many years.
The prognosis for Ross' syndrome is generally good. The condition is not life-threatening, but it can cause significant discomfort and inconvenience. The symptoms tend to progress slowly over many years.
==See Also==
==See Also==
* [[Adie's pupil]]
* [[Adie's pupil]]
* [[Hypohidrosis]]
* [[Hypohidrosis]]
* [[Areflexia]]
* [[Areflexia]]
==References==
==References==
<references />
<references />
{{stub}}
{{stub}}
[[Category:Medical conditions]]
[[Category:Medical conditions]]
[[Category:Neurological disorders]]
[[Category:Neurological disorders]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]

Latest revision as of 00:20, 4 April 2025


Ross' syndrome
Synonyms
Pronounce N/A
Specialty Neurology, Dermatology
Symptoms Anhidrosis, Areflexia, Miosis, Horner's syndrome
Complications N/A
Onset
Duration
Types N/A
Causes Unknown
Risks
Diagnosis Clinical evaluation, Autonomic testing
Differential diagnosis Holmes-Adie syndrome, Horner's syndrome, Diabetic neuropathy
Prevention N/A
Treatment Symptomatic management
Medication
Prognosis Variable
Frequency Rare
Deaths N/A


Ross' syndrome is a rare disorder characterized by a triad of symptoms: hypohidrosis (reduced ability to sweat), Adie's pupil (a pupil that does not react to light), and areflexia (absence of neurologic reflexes). It was first described by Douglas Ross in 1958.

Etiology[edit]

The exact cause of Ross' syndrome is unknown. It is thought to be due to damage to the autonomic nervous system, specifically the parasympathetic nervous system. This damage may be caused by an autoimmune process, but this is not confirmed.

Clinical Features[edit]

The main features of Ross' syndrome are:

  • Hypohidrosis: This is usually the first symptom to appear. It is often patchy and asymmetric, affecting one side of the body more than the other. It can lead to heat intolerance and fever.
  • Adie's pupil: This is a condition where the pupil is dilated and reacts slowly, or not at all, to light. It usually affects one eye but can affect both.
  • Areflexia: This is a lack of reflexes, particularly in the lower limbs. It can lead to difficulty with balance and coordination.

Diagnosis[edit]

Diagnosis of Ross' syndrome is based on the clinical features. There is no specific test for the condition. Other conditions that can cause similar symptoms, such as Horner's syndrome and Harlequin syndrome, should be ruled out.

Treatment[edit]

There is no cure for Ross' syndrome. Treatment is aimed at managing the symptoms. This may include using artificial tears for dry eyes, wearing cool clothing and staying in cool environments to manage heat intolerance, and physical therapy for balance and coordination problems.

Prognosis[edit]

The prognosis for Ross' syndrome is generally good. The condition is not life-threatening, but it can cause significant discomfort and inconvenience. The symptoms tend to progress slowly over many years.

See Also[edit]

References[edit]

<references />

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