Polyvinylpolypyrrolidone

Polyvinylpolypyrrolidone (also known as PVPP or Crospovidone) is a highly cross-linked modification of polyvinylpyrrolidone (PVP). It is used as a disintegrant in pharmaceutical tablets and is also used in the wine industry as a fining agent for white wines or some beers.

Chemical Structure

Polyvinylpolypyrrolidone is a water-insoluble polymer prepared from the monomer N-vinylpyrrolidone. It is a highly cross-linked version of polyvinylpyrrolidone, with the degree of cross-linking sufficient to render the polymer water-insoluble.

Uses

Pharmaceutical Industry

In the pharmaceutical industry, PVPP is used as a disintegrant, a substance that promotes the breakup of a tablet in the digestive tract after ingestion. It is included in the formulation of tablets for this purpose.

Wine Industry

In the wine industry, PVPP is used as a fining agent for white wines or some beers. It removes polyphenols, compounds that can cause astringency and some types of hazing in wines.

Safety

PVPP is generally considered safe for use in the pharmaceutical and food industries. It is not absorbed by the body and is therefore considered non-toxic and non-allergenic.

See Also

• Polyvinylpyrrolidone
• Pharmaceutical industry
• Wine industry

References

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