2-Aminopurine: Difference between revisions
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== 2-Aminopurine == | |||
[[File:2-Aminopurine.svg|thumb|right|Chemical structure of 2-Aminopurine]] | |||
'''2-Aminopurine''' is a purine analog that is used in molecular biology and genetics research. It is a derivative of [[adenine]], one of the four nucleobases in the nucleic acid of [[DNA]] and [[RNA]]. 2-Aminopurine is known for its ability to act as a fluorescent probe and its role as a mutagen. | |||
2-Aminopurine is a purine | |||
== | == Chemical Properties == | ||
2-Aminopurine is a structural analog of adenine, differing by the presence of an amino group at the 2-position of the purine ring. This modification allows it to pair with both [[thymine]] and [[cytosine]], which can lead to [[mutations]] during [[DNA replication]]. | |||
==Safety and Handling== | == Applications in Research == | ||
While 2- | |||
2-Aminopurine is widely used in research due to its fluorescent properties. It can be incorporated into [[nucleic acids]] and used to study [[DNA-protein interactions]], [[nucleic acid dynamics]], and [[enzyme mechanisms]]. Its fluorescence is sensitive to the local environment, making it a valuable tool for probing the structure and dynamics of nucleic acids. | |||
=== Mutagenic Effects === | |||
As a mutagen, 2-Aminopurine can induce base-pair substitutions by mispairing during DNA replication. This property is utilized in genetic studies to induce mutations and study their effects on [[gene function]] and [[protein expression]]. | |||
== Safety and Handling == | |||
While 2-Aminopurine is a useful research tool, it is important to handle it with care due to its mutagenic properties. Proper laboratory safety protocols should be followed to minimize exposure and prevent contamination. | |||
== Related Pages == | |||
* [[Adenine]] | * [[Adenine]] | ||
* [[ | * [[Mutagen]] | ||
* [[ | * [[Fluorescent probe]] | ||
* [[DNA replication]] | * [[DNA replication]] | ||
[[Category:Purines]] | [[Category:Purines]] | ||
[[Category:Molecular biology]] | [[Category:Molecular biology]] | ||
[[Category:Mutagens]] | [[Category:Mutagens]] | ||
Latest revision as of 10:47, 15 February 2025
2-Aminopurine[edit]
2-Aminopurine is a purine analog that is used in molecular biology and genetics research. It is a derivative of adenine, one of the four nucleobases in the nucleic acid of DNA and RNA. 2-Aminopurine is known for its ability to act as a fluorescent probe and its role as a mutagen.
Chemical Properties[edit]
2-Aminopurine is a structural analog of adenine, differing by the presence of an amino group at the 2-position of the purine ring. This modification allows it to pair with both thymine and cytosine, which can lead to mutations during DNA replication.
Applications in Research[edit]
2-Aminopurine is widely used in research due to its fluorescent properties. It can be incorporated into nucleic acids and used to study DNA-protein interactions, nucleic acid dynamics, and enzyme mechanisms. Its fluorescence is sensitive to the local environment, making it a valuable tool for probing the structure and dynamics of nucleic acids.
Mutagenic Effects[edit]
As a mutagen, 2-Aminopurine can induce base-pair substitutions by mispairing during DNA replication. This property is utilized in genetic studies to induce mutations and study their effects on gene function and protein expression.
Safety and Handling[edit]
While 2-Aminopurine is a useful research tool, it is important to handle it with care due to its mutagenic properties. Proper laboratory safety protocols should be followed to minimize exposure and prevent contamination.
