Veristrat
A blood-based test for cancer prognosis
Veristrat is a blood test used in the field of oncology to help determine the prognosis of patients with certain types of cancer, particularly non-small cell lung cancer (NSCLC). This test analyzes the proteomic profile of a patient's blood to classify them into different prognostic groups, which can guide treatment decisions.
Overview
Veristrat is a serum-based test that utilizes mass spectrometry to analyze the protein composition of a patient's blood. The test is designed to provide information about the likely course of the disease and the potential benefit of specific chemotherapy regimens. It is particularly used in the context of advanced NSCLC to help oncologists decide whether a patient is more likely to benefit from chemotherapy or targeted therapy.
Mechanism
The Veristrat test works by examining the proteomic profile of a patient's blood. It identifies specific patterns of protein expression that are associated with different outcomes in cancer treatment. The test categorizes patients into "Good" or "Poor" prognostic groups based on these patterns. Patients classified as "Good" are more likely to respond positively to certain treatments, while those in the "Poor" group may have a less favorable response.
Clinical Use
Veristrat is primarily used in the management of advanced non-small cell lung cancer. It helps in making informed decisions about the use of epidermal growth factor receptor (EGFR) inhibitors and other therapies. By providing prognostic information, Veristrat assists in tailoring treatment plans to the individual needs of patients, potentially improving outcomes and avoiding unnecessary side effects from ineffective treatments.
Advantages
One of the main advantages of Veristrat is its non-invasive nature, as it only requires a blood sample. This makes it a convenient option for patients compared to more invasive procedures like biopsy. Additionally, the test provides rapid results, allowing for timely decision-making in the management of cancer.
Limitations
While Veristrat offers valuable prognostic information, it is not a diagnostic test and should be used in conjunction with other clinical assessments and diagnostic tools. The test's predictive power is also limited to certain types of cancer and may not be applicable to all patients or cancer types.
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Contributors: Prab R. Tumpati, MD