Campylobacter upsaliensis

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A species of bacteria associated with gastrointestinal infections



Campylobacter upsaliensis is a species of bacteria within the genus Campylobacter. It is a Gram-negative bacterium that is known to cause gastrointestinal infections in humans. This species is often associated with domestic animals, particularly dogs and cats, which can act as reservoirs for the bacterium.

Morphology

Campylobacter upsaliensis is a spiral-shaped bacterium, characteristic of the Campylobacter genus. It is microaerophilic, requiring reduced levels of oxygen for growth. The bacterium is motile, possessing a single polar flagellum that allows it to move in a corkscrew motion.

Pathogenicity

Campylobacter upsaliensis is an emerging pathogen in human gastroenteritis. It is less commonly identified than Campylobacter jejuni and Campylobacter coli, but it can cause similar symptoms, including diarrhea, abdominal pain, and fever. The infection is typically self-limiting, but in some cases, it may require antibiotic treatment.

Transmission

The primary mode of transmission of Campylobacter upsaliensis to humans is through contact with infected animals, particularly pets such as dogs and cats. The bacterium can also be transmitted through the consumption of contaminated food or water.

Diagnosis

Diagnosis of Campylobacter upsaliensis infection is typically performed through stool cultures. However, this species is more difficult to culture than other Campylobacter species, which can lead to underdiagnosis. Molecular methods such as PCR are increasingly used for detection.

Treatment

Most infections with Campylobacter upsaliensis are self-limiting and do not require treatment. In severe cases, antibiotics such as azithromycin or ciprofloxacin may be prescribed. It is important to maintain hydration during the course of the illness.

Prevention

Preventive measures include practicing good hygiene when handling pets, ensuring proper food safety practices, and avoiding consumption of undercooked or contaminated food.

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Contributors: Prab R. Tumpati, MD