Wharton's jelly
Wharton's Jelly
Wharton's Jelly (/ˈwɔːrtənz ˈdʒɛli/), named after the English anatomist Thomas Wharton, is a gelatinous substance within the umbilical cord that provides cushioning and support to the umbilical veins and umbilical arteries.
Etymology
The term "Wharton's Jelly" is derived from the name of Thomas Wharton, who first described this substance in his publication "Adenographia" in 1656. The term "jelly" refers to the gelatinous consistency of the substance.
Structure and Function
Wharton's Jelly is a mucous connective tissue composed primarily of hyaluronic acid and chondroitin sulfate, two substances that give it a gelatinous consistency. It surrounds and cushions the umbilical vessels, preventing compression and ensuring continuous blood flow to the developing fetus.
Clinical Significance
Wharton's Jelly is of clinical interest due to its rich source of mesenchymal stem cells (MSCs). These cells have the potential to differentiate into a variety of cell types, including bone, cartilage, muscle, and fat cells. This makes Wharton's Jelly a potential source for cell therapy and regenerative medicine.
Related Terms
- Umbilical cord
- Mesenchymal stem cells
- Hyaluronic acid
- Chondroitin sulfate
- Cell therapy
- Regenerative medicine
External links
- Medical encyclopedia article on Wharton's jelly
- Wikipedia's article - Wharton's jelly
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