Vesiculo-vacuolar organelle
Vesiculo-vacuolar organelle
Vesiculo-vacuolar organelle (pronunciation: ve-si-cu-lo-va-cu-lar or-gan-elle) is a specialized structure found within endothelial cells. These organelles are characterized by their unique structure, which consists of a network of interconnected vesicles and vacuoles.
Etymology
The term "vesiculo-vacuolar organelle" is derived from the Latin words "vesicula" meaning small sac or bladder, and "vacuus" meaning empty or void. The term "organelle" is derived from the Latin word "organum" meaning instrument or tool, and the Greek word "elle" meaning small. Thus, the term can be translated as "small tool consisting of empty sacs".
Function
The primary function of vesiculo-vacuolar organelles is to facilitate the process of transendothelial cell migration, which is crucial for the movement of leukocytes and cancer cells across the endothelial barrier. They are also involved in the process of angiogenesis, the formation of new blood vessels from pre-existing ones.
Related Terms
- Endothelial cells: These are cells that line the interior surface of blood vessels and lymphatic vessels.
- Vesicles: These are small, membrane-enclosed sacs that store and transport substances within a cell.
- Vacuoles: These are membrane-bound organelles that are involved in the intracellular digestion and release of waste products.
- Transendothelial cell migration: This is the process by which cells move across the endothelial barrier.
- Leukocytes: These are white blood cells that are involved in protecting the body against both infectious disease and foreign invaders.
- Angiogenesis: This is the physiological process through which new blood vessels form from pre-existing vessels.
External links
- Medical encyclopedia article on Vesiculo-vacuolar organelle
- Wikipedia's article - Vesiculo-vacuolar organelle
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