Uricosuric
Uricosuric
Uricosuric (pronounced: yoo-rih-ko-SUR-ik) is a term that refers to a class of drugs or substances that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in the blood.
Etymology
The term "uricosuric" is derived from the Latin words "urica" meaning "uric acid" and "surere" meaning "to cast out".
Mechanism of Action
Uricosuric agents work by blocking the reabsorption of urate, which is a salt derived from uric acid, in the kidneys. This leads to an increased excretion of uric acid in the urine.
Uses
Uricosuric drugs are primarily used in the treatment of gout, a type of arthritis that occurs when uric acid builds up in the blood and causes joint inflammation. They are also used to prevent kidney stones that are caused by high levels of uric acid in the urine.
Examples
Examples of uricosuric drugs include Probenecid and Sulfinpyrazone. These drugs are often used in combination with other medications to treat gout.
Side Effects
Common side effects of uricosuric drugs include stomach pain, kidney stones, and rash. More serious side effects can include blood disorders and severe allergic reactions.
Related Terms
External links
- Medical encyclopedia article on Uricosuric
- Wikipedia's article - Uricosuric
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