Tuberoinfundibular pathway

The Tuberoinfundibular pathway (pronunciation: too-ber-oh-in-fun-dib-yuh-lar path-way) is a neural pathway that originates in the hypothalamus and extends to the pituitary gland. This pathway plays a crucial role in the regulation of prolactin secretion.

Etymology

The term "Tuberoinfundibular pathway" is derived from the Latin words 'tuber' meaning lump, 'infundibulum' meaning funnel, and 'pathway' meaning route. This refers to the route that extends from the tuber cinereum, a region in the hypothalamus, to the infundibulum, a part of the pituitary gland.

Function

The primary function of the tuberoinfundibular pathway is to regulate the secretion of prolactin, a hormone that stimulates milk production, from the anterior pituitary gland. It does this by releasing dopamine, a neurotransmitter that inhibits prolactin secretion.

Clinical significance

Disruption of the tuberoinfundibular pathway can lead to a variety of medical conditions. For example, certain antipsychotic medications can block dopamine receptors in this pathway, leading to an overproduction of prolactin, a condition known as hyperprolactinemia. This can cause symptoms such as irregular menstrual periods in women and erectile dysfunction in men.

Related terms

Dopamine: A neurotransmitter that plays several important roles in the brain and body.
Hypothalamus: A region of the brain responsible for the production of many of the body's essential hormones.
Pituitary gland: A small, pea-sized gland that plays a major role in regulating vital body functions and general wellbeing.
Prolactin: A hormone produced in the pituitary gland that plays a role in lactation and fertility.
Hyperprolactinemia: A condition characterized by an excess amount of prolactin in the blood.

External links

Medical encyclopedia article on Tuberoinfundibular pathway
Wikipedia's article - Tuberoinfundibular pathway

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Tuberoinfundibular pathway