Trovafloxacin
Trovafloxacin
Trovafloxacin (pronounced: troh-vuh-flox-uh-sin) is a broad-spectrum quinolone antibiotic that was first introduced by Pfizer in 1997 under the brand name Trovan.
Etymology
The name "Trovafloxacin" is derived from the class of drugs it belongs to, the quinolones, and its chemical structure. The prefix "trova-" is a reference to the tropane ring in its structure, while "-floxacin" is a common suffix for quinolone antibiotics.
Usage
Trovafloxacin is used to treat a variety of bacterial infections, including those caused by Gram-positive and Gram-negative organisms. It works by inhibiting the enzymes DNA gyrase and topoisomerase IV, which are necessary for bacterial DNA replication, transcription, repair, and recombination.
Side Effects
Common side effects of trovafloxacin include nausea, diarrhea, and abdominal pain. In rare cases, it can cause serious liver damage, leading to its restricted use in the United States.
Related Terms
External links
- Medical encyclopedia article on Trovafloxacin
- Wikipedia's article - Trovafloxacin
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